Clinical trials: Diaphragm
Covid19, Diaphragm Injury
Respiratory Muscle Assesment in COVID-patients Without Hospitalization
Fatigue and exercise intolerance after survived COVID-19-infection might be related to weakness of the respiratory muscles. The aim of the project is to measure respiratory muscle function and strength in our respiratory…
- Trial name
- RMA-COVID-19 (NCT06105450)
- Testing
- Comprehensive assessment of respiratory muscle function.
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- RWTH Aachen University
Abdominal Injury, Pelvic Fracture
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Unrecognized abdominal and pelvic injuries can result in catastrophic disability and death. Sporadic reports of "occult" injuries have generated concern, and physicians, fearing that they may miss such an injury, have adopted the…
- Conditions
- Abdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine Injury
- Trial name
- NEXUS AP CT (NCT04937868)
- Testing
- There are no interventions associated with this study
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- University of California, Los Angeles
Weaning Mechanical Ventilation, Ultrasonography
The Relationship Between Diaphragm Function Assessed by Ultrasound and Weaning Success in Mechanically Ventilated Patients in the ICU
The diaphragm is the most important muscle involved in the respiratory system and is solely responsible for approximately 65-80% of vital capacity.
- Conditions
- Weaning Mechanical Ventilation, Ultrasonography, Intensive Care (ICU), Assesment of Diaphragmatic Function by Ultrasound to Predict Weaning Success in Mechanical Ventilated Intensive Care Unit Patients
- Trial name
- ICU (NCT07332403)
- Testing
- Diaphragm ultrasound before weaning procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Low Back Pain, Diaphragm; Relaxation
Diaphragmatic Release for Low Back Pain
Low back pain is one of the most common musculoskeletal disorders, significantly affecting the quality of life of individuals. In non-specific low back pain, a lack of stabilization in the core region negatively impacts the…
- Trial name
- NCT07298109
- Testing
- Manual diaphragm release, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Neck Pain, Diaphragm
Effects of Diaphragmatic Resistance Training in People With Chronic Neck Pain.
With increasing usage of electronic devices and sedentary lifestyle, chronic neck pain has become a more prevalent musculoskeletal disorder around the world.
- Conditions
- Neck Pain, Diaphragm, Exercise Training, Inhalation
- Trial name
- NCT05529641
- Testing
- Diaphragmatic resistance training, Cervical stabilization exercise
- Where
- Taiwan
- Volunteers
- 71 people
- Sponsor
- National Cheng Kung University
Diaphragm Ultrasound, Diaphragm Dysfunction
Correlation of Diaphragm Shear-Wave Elastography With Transdiaphragmatic Pressure in Healthy Adults: a Feasibility Study
Changes in intrapleural pressure after lung volume reduction in Chronic Obstructive Pulmonary disease (COPD) patients can lead to complications, including an increased risk of pneumothorax.
- Conditions
- Diaphragm Ultrasound, Diaphragm Dysfunction, Health Adult Subjects
- Trial name
- PLEASSURE 1 (NCT07253480)
- Testing
- shear wave elastography of the diaphragm
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Isala
Critical Illness, Intensive Care Units (ICUs)
Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit
The goal of this observational study is to measure effort using esophageal pressure measurements, oxygen consumption and diaphragm activity in mechanically ventilated Intensive Care Unit patients during a Spontaneous Breathing…
- Conditions
- Critical Illness, Intensive Care Units (ICUs), Weaning Failure, Mechanical Ventilation
- Trial name
- SERA-Effort (NCT07109570)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
Diaphragm Issues
STIMIT Activator 1 IDE Study
The study is a prospective, multi-center, randomized, controlled study using adaptive design to assess the evidence of safety and performance of the STIMIT Activator 1 System in the treatment of patients who have been…
- Trial name
- NCT05883163
- Testing
- Stimit Activator 1
- Where
- 4 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- Stimit AG
BIPAP Biphasic Intermittent Positive Airway Pressure, Diaphragm Issues
The Effect of BIPAP on Diaphragmatic Function
This research is designed to evaluate how long-term treatment with Bilevel Positive Airway Pressure (BiPAP) influences diaphragm function in patients with Chronic Obstructive Pulmonary Disease (COPD) who suffer from chronic…
- Conditions
- BIPAP Biphasic Intermittent Positive Airway Pressure, Diaphragm Issues, Ultrasound Diagnostics, COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07193017
- Testing
- BIPAP
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Demiroglu Bilim University
Ventilation Therapy; Complications, Diaphragm Disease
Real-time Effort Driven VENTilator Management
This study is a Phase II controlled clinical trial that will obtain comprehensive, serial assessments of respiratory muscle strength and architecture to understand the evolution of ventilator-induced respiratory muscle weakness…
- Conditions
- Ventilation Therapy; Complications, Diaphragm Disease, Pediatric Respiratory Diseases
- Trial name
- REDvent (NCT03266016)
- Testing
- Computerized Ventilator Protocol, Esophageal Manometry, Respiratory Inductance Plethysmography (RIP)
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Children's Hospital Los Angeles
Diaphragm Ultrasound, Electrical Cardiometry
Diaphragmatic Ultrasound and Thoracic Fluid Content for Prediction of Non-Invasive Ventilation Failure in Neonates
This research assessed diaphragmatic ultrasound and thoracic fluid content (TFC) as potential early predictive tools for detecting NIV failure in preterm neonates.
- Conditions
- Diaphragm Ultrasound, Electrical Cardiometry, Non Invasive Ventilation (NIV), RDS of Prematurity
- Trial name
- NCT07148102
- Testing
- Diaphragmatic US, EC
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Lamiaa Khaled Zidan
Migraine, Migraine Disease
Diaphragm Relaxation Techniques, Diaphragmatic Breathing Exercises for Migraine Patients
Migraine is a neurological disease characterized by recurring headaches. It is a significant public health problem of the top reasons for disability throughout the world.
- Conditions
- Migraine, Migraine Disease, Manuel Therapy, Diaphragm Relaxation
- Trial name
- NCT07145372
- Testing
- Manual therapy, Diaphragmatic relaxation technique, Shoulder ROM exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Seda Saka
Diaphragm Issues
Assessment of Diaphragmatic Mobility in Dyspneic Patients With Different Types of Interstitial Lung Diseases
dyspnea and impaired exercise capacity in IPF patients can be related, at least in part, to respiratory muscle dysfunction, in particular to diaphragm functionality.
- Trial name
- NCT07131072
- Testing
- daiphragm mobility by ultrsound, spirometry ,DLCo
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Tracheostomy, Cough
Objective Evaluation of Cough Effort in Tracheotomized Patients (LOST Study)
This study aims to evaluate how well tracheotomized patients can cough before and after their tracheostomy tube is removed. Cough strength is measured using two different tools-Peak Flow and Lorio.
- Conditions
- Tracheostomy, Cough, Weaning, Respiratory Function Tests
- Trial name
- NCT07061561
- Testing
- Peak Expiratory Flow Measurement Using Peak Flow Meter and Lorio Device
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Lung, Diaphragm
Lung and Diaphragm Ultrasound in Predicting Extubation and Weaning of Mechanically Ventilated Patients in Intensive Care Unit
This study aims to evaluate the role of lung ultrasound score (LUS), diaphragmatic excursion (DE), and diaphragmatic thickening fraction (DTF) as predictors of successful extubation in mechanically ventilated patients in the…
- Conditions
- Lung, Diaphragm, Ultrasound, Extubation
- Trial name
- NCT07057804
- Testing
- Lung Ultrasound, Diaphragm Ultrasound
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kafrelsheikh University
End-Expiratory Lung Impedance, Respiratory Rate
Asymmetrical High Flow Nasal Cannula and End-Expiratory Lung Impedance
Objective: The primary aim is to assess end-expiratory lung impedance (EELI) changes during the application of high-flow oxygen therapy using asymmetric nasal cannulae, comparing conditions with the mouth closed and open in…
- Conditions
- End-Expiratory Lung Impedance, Respiratory Rate, Diaphragm Thickness Fraction, Diaphragm Excursion
- Trial name
- EELI and AHFNC (NCT06674629)
- Testing
- High flow oxygen therapy
- Where
- Argentina
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Argentinian Intensive Care Society
Diaphragm
Recruitment of the Diaphragm and Sternocleidomastoid Muscle During Loaded Inspiration on Varying Sitting Support in Healthy Adults
This is a cross-sectional obsessional study. This study explores how different sitting conditions affect two important muscles-the diaphragm and the sternocleidomastoid (SCM)-work during breathing exercises.
- Trial name
- NCT07007923
- Where
- Hong Kong
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Geriatric, Sarcopenia
Investigation of Respiratory Muscle Sarcopenia in Geriatric Individuals
The increase in the elderly population worldwide necessitates further research on age-related physiological changes and health problems related to these changes in geriatric individuals.
- Conditions
- Geriatric, Sarcopenia, Diaphragm
- Trial name
- NCT06994598
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Diaphragm Dysfunction
Incidence and Impact of ICU-acquired Diaphragm Weakness
ICU survivors are at an increased risk of hospital and ICU readmission. Among the complications of ICU stay, diaphragmatic dysfunction is common, with a prevalence of 60 to 80%, and is associated with increased mortality and…
- Trial name
- PRODIGY (NCT06420999)
- Testing
- Diaphragmatic ultrasound and data collection
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ventilator Lung, Ventilator-Induced Lung Injury
Phrenic Identification in the ICU
This will be a prospective observational study where the investigator will scan patients' necks with an ultrasound and look for anatomical landmarks that may help identify the phrenic nerve.
- Conditions
- Ventilator Lung, Ventilator-Induced Lung Injury, Diaphragm Disease, Phrenic Nerve
- Trial name
- NCT05875883
- Testing
- Neck ultrasound
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Unity Health Toronto