Clinical trials: Diaphragms
Hernia, Hernia Abdominal Wall
Image-Guided Herniorrhaphy Study
This pilot clinical study will evaluate the safety and effectiveness of a new image-guided, needle-based approach for repairing abdominal or groin hernias in adults who are unable or unwilling to undergo traditional open or…
- Conditions
- Hernia, Hernia Abdominal Wall, Ventral Hernia, Inguinal Hernia
- Trial name
- NCT07267494
- Testing
- Image-Guided Herniorrhaphy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Mechanical Ventilation
The Ratio of Diaphragmatic Movement Between the Midaxillary Line and the Midclavicular Line Predicts the Success Rate of Weaning From Mechanical Ventilation
This study will provide individualized objective indicators for patients undergoing invasive mechanical ventilation. It will set specific assessment parameters for weaning and extubation for different patients, increase the…
- Trial name
- NCT07235956
- Testing
- Observe the ratio of diaphragmatic excursion between the midaxillary line and the midclavicular line in the successful group of invasive mechanical ventilation weaning.
- Volunteers
- 100 people
- Sponsor
- Zheng Qingjiang
Diaphragm Issues
Assessment of Diaphragmatic Mobility in Dyspneic Patients With Different Types of Interstitial Lung Diseases
dyspnea and impaired exercise capacity in IPF patients can be related, at least in part, to respiratory muscle dysfunction, in particular to diaphragm functionality.
- Trial name
- NCT07131072
- Testing
- daiphragm mobility by ultrsound, spirometry ,DLCo
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Diabetes Type II
Effects of Core Strengthening Exercises With Diapgragmatic Breathing Versus Core Strengthening Exercises With Pilate Breathing in Diabetes Type II Patients
Diabetes type II is a metabolic syndrome involving high sugar levels known as hyperglycemia. It can impair pulmonary function through reduced lung elasticity and gas exchange and weaken core muscles due to inflammation and muscle…
- Trial name
- NCT07290231
- Testing
- Core Strengthening with Diaphragmatic Breathing, core strengthening with pilate breathing
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Foundation University Islamabad
Healthy Individuals (Controls)
Effects of Combined Exercise Training Modality
This study aims to investigate the effects of combined Inspiratory Muscle Training and aerobic exercise on diaphragm and pulmonary functions, respiratory muscle function, performance, and body composition
- Trial name
- NCT06742372
- Testing
- combined inspiratory and aerobic exercise training, aerobic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gazi University
Paraesophageal Hernia
Posterior Rectus Sheath Hiatal Augmentation in Paraesophageal Hernia Repair
This study will be a prospective observation study of the use of PoRSHA for repair in patients with challenging paraesophageal hernias.
- Trial name
- NCT06551077
- Testing
- POSTERIOR RECTUS SHEATH HIATAL AUGMENTATION (PORSHA)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Epigastric Hernia Repair, Erector Spinae Plane Block
Ultrasound Guided Erector Spinae Plane Block on Post-operative Pain and Diaphragmatic Dysfunction in Epigastric Hernia
The aim of this study is to assess the efficacy of ultrasound guided erector Spinae plane block on postoperative pain score and diaphragmatic dysfunction in obese patients undergoing Epigastric hernia repair.
- Conditions
- Epigastric Hernia Repair, Erector Spinae Plane Block, Post Operative Pain, Diaphragmatic Dysfunction
- Trial name
- NCT05516901
- Testing
- The erector spinae plane block group, Control group
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tanta University
Stroke, Hemiplegia
Air Stacking-Assisted Diaphragmatic Breathing in Stroke
The purpose of this study is to investigate whether a diaphragmatic breathing exercise using the air stacking technique can improve respiratory function and trunk control in patients with stroke.
- Trial name
- NCT07577076
- Testing
- Air stacking-assisted diaphragmatic breathing, diaphragmatic breathing
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- jang ji-hun
Reflux Disease, Gastro-Esophageal
Breathing Exercises in Patients With Gastroesophageal Reflux
The aim of this study was to examine the effects of diaphragmatic breathing exercises combined with relaxation exercises on patient-reported reflux symptoms, quality of life, anxiety, and depression levels in patients diagnosed…
- Trial name
- NCT06812650
- Testing
- Medical treatment, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Karabuk University
Gastroesophageal Reflux Disease, Hiatal Hernia
Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT Study
The objective of the study is to evaluate the relative merits, safety and effectiveness of the EsophyX transoral device in performing an advanced TIF procedure in patients with "troublesome symptoms" as defined by the Montreal…
- Trial name
- RESPECT (NCT01136980)
- Testing
- TIF Transoral Fundoplication
- Where
- 9 sites in United States
- Volunteers
- 129 people
- Sponsor
- EndoGastric Solutions
Hernia, Hiatal
Laparoscopic Repair of Giant Hiatal Hernias With Nitinol-framed Lightweight Polytetrafluoroethylene Mesh
This study is prospective randomized trial enrolling at least 50 participants which compares efficacy and safety of two alternative methods of laparoscopic hiatal repair for giant (i.e.
- Trial name
- GIANT (NCT01780285)
- Testing
- Nitinol-framed lightweight PTFE mesh for hiatal repair, Partially absorbable lightweight mesh for hiatal repair
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Odessa National Medical University
Invasive Ventilatory Support
NAVADYN11 : Hemodynamic Impact of a New Ventilatory Support Mode With Diaphragmatic Synchronization
Despite spectacular advances since the 90s mechanical ventilation used in intensive care units are amply associated with cardio-respiratory complications: nosocomial pneumonia, lung parenchyma lesions induced by ventilation…
- Trial name
- NCT01490710
- Testing
- collection of clinical and biological parameters, assign optimal ventilatory mode
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Nantes University Hospital
Diaphragmatic Paralysis
Ultrasound-guided Interscalene Block:3mL Ropi Provide Similar Analgesia to 5mL and Less Diaphragmatic Paralysis
Ropivacaine for ultrasound-guided interscalene block: 3mL provide similar analgesia to 5mL with less diaphragmatic paralysis in shoulder arthroscopy surgeries
- Trial name
- NCT04317235
- Testing
- Ropivacaine 0.5% Injectable Solution
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint George Hospital
Hypertension, FXTAS
Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia
To study whether heart rate variability training and respiratory coherence can improve hypertension in individuals with FXTAS. All patients will receive HRV biofeedback training for 20 sessions.
- Trial name
- NCT03816540
- Testing
- HRV and respiratory coherence biofeedback
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Mechanical Ventilation Complication, Diaphragm Injury
Respiratory Muscle Structure and Function in Mechanically Ventilated Patients and Long-term Outcomes
Air is normally pumped in and out of the lungs by the muscles that contribute to inhalation and exhalation, called the respiratory muscles.
- Conditions
- Mechanical Ventilation Complication, Diaphragm Injury, Lung Injury, Respiratory Insufficiency
- Trial name
- RESPIRE (NCT05857774)
- Testing
- Sonographic measurements, Physiological measurements, Biological measurements
- Where
- Canada
- Volunteers
- 230 people
- Sponsor
- University Health Network, Toronto
Abdominoplasty Surgery
Correlation Between Intra-abdominal Pressure and Diaphragmatic Mobility in Women Submitted to Abdominoplasty After Bariatric Surgery
Background: Plication of the rectus abdominis muscles leads to an increase in intra-abdominal pressure (IAP), which may negatively impact the respiratory system due to its effects on diaphragmatic mobility (DM).
- Trial name
- NCT06648694
- Testing
- Abdominoplasty surgery, Abdominoplasty
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Esophageal Atresia With Tracheo-esophageal Fistula, Congenital Diaphragmatic Hernia
Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases
This is a pilot randomised controlled trial comparing open versus thoracoscopic surgery for repair of oesophageal atresia with tracheo-oesophageal fistula or congenital diaphragmatic hernia in neonates.
- Trial name
- CO2 (NCT01467245)
- Testing
- Hypercapnia during thoracoscopy, Open surgery
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Respiratory Insufficiency, Pneumonia
Diaphragm Dysfunction and Ultrasound Perioperatively
This study aims at determining whether diaphragm ultrasound examining diaphragm thickening fraction, excursion and density before and after surgery can predict respiratory complications in the postoperative period.
- Conditions
- Respiratory Insufficiency, Pneumonia, Desaturation of Blood, Tachypnea
- Trial name
- DiaphPeriop (NCT05906030)
- Testing
- Diaphragm ultrasound
- Where
- 2 sites in Sweden
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Hiatal Hernia, Paraesophageal, Hiatal Hernia Large
Laparoscopic Nissen Versus Toupet Fundoplication for Hiatal Hernia.
This randomized controlled trial compares laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication in patients undergoing surgical treatment for hiatal hernia associated with gastroesophageal reflux disease.
- Conditions
- Hiatal Hernia, Paraesophageal, Hiatal Hernia Large, Hiatal Hernia With Gastroesophageal Reflux Disease
- Trial name
- NCT07718828
- Testing
- Laparoscopic Nissen Fundoplication, Laparoscopic Toupet Fundoplication
- Where
- Bulgaria
- Volunteers
- 200 people
- Sponsor
- Sofia Med Hospital
Inhalation Injury
Intermittent-pneumatic Compression in Inhalation-injury Children: Effects on Diaphragm Mobility and Pulmonary Function
inhalation injury is very common in infants, young, children. complications of this problems are low pulmonary functions and limited mobility of main inspiratory muscle.
- Trial name
- NCT05915494
- Testing
- intermittent pneumatic compression, physiotherapy, and walking, physiotherapy and walking
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
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