Clinical trials: Diaphragms
Hypoxic Respiratory Failure
Diaphragmatic Ultrasound to Predict the Therapeutic Effect of High-flow Nasal Cannula Oxygen Therapy
Follow-up was conducted for every patient requiring high-flow nasal cannula oxygen therapy in district 1 of the Intensive Care Department of Chenzhou NO.1 People's Hospital.
- Trial name
- NCT06336265
- Testing
- Diaphragm ultrasound
- Volunteers
- 269 people
- Sponsor
- Xingui Dai
Ventilator-induced Diaphragm Dysfunction, VIDD
Evaluation of heepSync, a Novel Algorithm for Transcutaneous Electrical Stimulation of Respiratory Muscles in Mechanically Ventilated Patients.
Up to 76% of ICU patients on mechanical ventilation develop significant respiratory muscle atrophy within the first 24 hours, contributing to prolonged ventilation, increased morbidity, and higher healthcare costs.
- Conditions
- Ventilator-induced Diaphragm Dysfunction, VIDD, Weaning Failure
- Trial name
- NCT07363902
- Testing
- Heecap
- Where
- 3 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Tesai Care SL
Diaphragmatic Plication, Unilateral Diaphragmatic Paralysis
Clinical and Sonographic Diaphragm Evaluation Post-plication
Objectives: We aim to clarify the role of diaphragm ultrasonography (DUS) in evaluating the outcome of surgical diaphragmatic plication (SDP) in adults with symptomatic unilateral diaphragmatic paralysis (UDP).
- Conditions
- Diaphragmatic Plication, Unilateral Diaphragmatic Paralysis, Diaphragm Ultrasonography
- Trial name
- NCT04052295
- Testing
- surgical diaphragmatic plication
- Volunteers
- 40 people
- Sponsor
- South Valley University
Neurosurgery, Phrenic Nerve Stimulation
Intraoperative Diaphragmatic Neuromodulation
This prospective, single-center, randomized controlled clinical trial aims to investigate the impact of intraoperative phrenic nerve stimulation (i.e., diaphragmatic neuromodulation) on postoperative complications in…
- Conditions
- Neurosurgery, Phrenic Nerve Stimulation, Postoperative Delirium
- Trial name
- NCT06518707
- Testing
- Phrenic nerve stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Sanbo Brain Hospital
Weaning Mechanical Ventilation, ICU Ill Patients
Diaphragmatic Ultrasonography in Difficult Weaning
Weaning from mechanical ventilation (MV) is a gradual process that includes several steps until the complete withdrawal of ventilatory support.
- Conditions
- Weaning Mechanical Ventilation, ICU Ill Patients, Diaphragm Dysfunction
- Trial name
- DUS-WEAN (NCT07751237)
- Testing
- Diaphragmatic ultrasound
- Where
- Brazil
- Volunteers
- 220 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Restrictive Lung Diseases
Effects of Inspiratory Muscle Training and Positive Expiratory Pressure on Mechanically Ventilated Restrictive Lung Disease Patients
Restrictive lung diseases (RLD) represent a significant cause of morbidity, often necessitating intensive interventions such as mechanical ventilation due to diminished lung compliance (LC) and reduced total lung capacity (TLC).
- Trial name
- NCT07867730
- Testing
- Inspiratory muscle training, Conventional Chest Physical Therapy
- Where
- 3 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Emphysema
Assessing the DIAphragM Before ANd After Endobronchial Valve Treatment
Rationale: The diaphragm is the principal respiratory muscle, which separates the thorax from the abdomen. Hyperinflation of the lung places the diaphragm at a mechanical disadvantage, shortens its operating length and changes…
- Trial name
- DIAMANT (NCT04735731)
- Testing
- Echography
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- University Medical Center Groningen
Diaphragmatic Dysfunction
Comparative Ultrasonic Study of Post Operative Diaphragmatic Dysfunction in Abdominal and Head and Neck Surgery
Diaphragmatic dysfunction (DD) is one of the main risk factors for post operative respiratory distress syndrome. Ultrasonography is a diagnosis tool for DD but few studies have been published.
- Trial name
- Under the Dome (NCT01737775)
- Testing
- Diaphragmatic amplitude measurement
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
COPD, COPD Exacerbation
Ultrasonographic Evaluation of Diaphragm and Quadriceps in Chronic Obstructive Pulmonary Disease (COPD) Patients
The purpose of this study is to evaluate the prognostic role of echographic diaphragmatic assessment and vastus lateralis muscle ultrasound (US) in two independent populations of patients hospitalized for exacerbated Chronic…
- Trial name
- EDIFEB (NCT04509128)
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele Roma
Stroke
Characteristics in Doppler Ultrasound of the Carotid Diaphragm Responsible for an Ischemic Stroke
Carotid diaphragms are a non-atheromatous arterial cause of cerebral infarction, especially in young people (≤65 years old). This anomaly is more common in the African or African-American population, although it is more and more…
- Trial name
- DIADOP (NCT04442074)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Mechanical Ventilation Complication, Diaphragm Injury
Effect of Diaphragm Stimulation During Surgery
During major surgical procedures general anesthesia is used to make the patient unconscious. General anesthesia insures that the patient is unaware of any pain caused by surgery.
- Trial name
- NCT03303040
- Testing
- Electrical stimulation of hemidiaphragm
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Acute Psychophysiological Responses to Heart Rate Variability Biofeedback
Effects of Brief Heart Rate Variability Biofeedback on Physiological and Emotional Responses
This completed randomized laboratory study investigated the immediate effects of a single 10-minute session of heart rate variability biofeedback (HRV-B) on cardiac activity, forehead physiological signals, and emotional…
- Trial name
- NCT07911215
- Testing
- Psychoeducational Video Viewing, Heart Rate Variability Biofeedback
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Diaphragmatic Eventration
Two Procedures for Uniportal Video Assisted Thoracoscopic Surgery to Treat Severe Cases of Diaphragmatic Eventration in Adult
highly elevated abnormal diaphragm is lowered to normal position by runuing suture accordion shaped or cut part of diphragm by stabler
- Trial name
- NCT07035366
- Testing
- stabled resection, running sutures
- Where
- 3 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Acute Hypoxemic Respiratory Failure
Predictors of HFNC Failure in Patients With AHRF Using Diaphragm Ultrasound
Ultrasound of the diaphragm is an easily reproducible bedside tool that provides a non-invasive measurement of inspiratory muscle function and respiratory efficiency.
- Trial name
- ULTRAFLOW (NCT06096376)
- Testing
- Diaphragm Ultrasound
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Volleyball Players
Diaphragmatic Facilitation and Upper Extremity Performance in Volleyball Players
The diaphragm contributes to both respiration and trunk stabilization. Effective diaphragmatic function may support postural control, force transfer, and upper extremity performance during dynamic activities.
- Trial name
- NCT07784517
- Testing
- Diaphragmatic Facilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istinye University
Adults With Cardiopulmonary Disease at Risk of Prolonged Weaning From Mechanical Ventilation
Neurally Adjusted Ventilatory Assist in Adults at Risk of Delayed Weaning From Mechanical Ventilation
Many patients admitted to intensive care have heart or lung problems. Patients with these conditions often require longer durations of support from breathing machines.
- Trial name
- RESTUS (NCT01826890)
- Testing
- NAVA Technology
- Where
- United Kingdom
- Volunteers
- 78 people
- Sponsor
- King's College Hospital NHS Trust
Ventilator Induced Lung Injury
Percutaneous Temporary Placement of a Phrenic Nerve Stimulator for Diaphragm Pacing, a First in Human Trial
Study conducted to confirm phrenic nerve stimulation using the Lungpacer LIVE Catheter, confirm capture of the diaphragm and confirm that the diaphragm can be paced in synchrony with mechanical ventilator breaths.
- Trial name
- NCT02670460
- Testing
- LIVE Catheter
- Where
- Paraguay
- Volunteers
- 24 people
- Sponsor
- Lungpacer Medical Inc.
Sports Physical Therapy, Athletic Injuries
Acute Effects of Inspiratory Muscle Load on Diaphragmatic Recovery in Athletes
This randomized controlled trial investigates the acute effects of inspiratory muscle warm-up and fatigue on diaphragmatic function in professional basketball players.
- Conditions
- Sports Physical Therapy, Athletic Injuries, Healthy
- Trial name
- NCT07046637
- Testing
- Inspiratory muscle fatigue group, Inspiratory muscle warm-up group
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Mechanical Low Back Pain, Respiratory Functions
Core Stability Exercise Versus Diaphragmatic Release on Respiratory Functions on Physical Therapists With Low Back Pain
To compare between core stability exercise and diaphragmatic release on respiratory functions on physical therapists with low back pain.
- Trial name
- NCT05860283
- Testing
- Core stabilization exercise using pressure biofeedback unit, Diaphragmatic release technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Obesity, Hiatal Hernia
Comparative 3-year Study of Nissen-sleeve vs. Sleeve Plus Cruroplasty in Obese Patients With Hiatal Hernia
The success of laparoscopic sleeve gastrectomy (LSG) is not only due to its proven efficacy in the treatment of obesity and associated to comorbidities in the short and long term, but also because it is considered as less…
- Trial name
- HH-N Sleeve (NCT06835790)
- Testing
- Ph-measurement, Questionnaires, gastroduodenal transit
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Elsan
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