Clinical trials: Diaphyseal Fracture
Tibial Fractures
Management of Closed Diaphyseal Displaced Leg Fractures in Children and Adolescents
Most displaced tibial shaft fractures in pediatric patients have traditionally been treated after reduction by cast immobilization with good long-term results.
- Trial name
- FFD (NCT06503718)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Strasbourg, France
Clavicle Fracture
Surgically Treated Displaced Mid-diaphyseal Clavicle Fractures
This prospective, multi-centre study aims to determine clinical, radiographic, and patient-reported outcomes (PROMs) following surgical fixation of displaced mid-diaphyseal clavicle fractures and to compare implant removal rates…
- Trial name
- NCT05867355
- Testing
- surgical fixation
- Where
- Canada
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Clavicle Fracture
Percutaneous Versus Open Plate Fixation of Diaphyseal Clavicle Fractures
This is a prospective, level II evidence comparison between two cohorts. This study is designed to compare the percutaneous versus open approach for plate fixation of diaphyseal clavicle fractures.
- Trial name
- NCT01405703
- Testing
- xrays
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Utah
Proximal Humeral Fracture, Proximal Tibia Fractures
PMCF Study on the Safety, Performance and Clinical Benefits Data of the Zimmer® Plates and Screws System
The study is a monocentric, retro- and prospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to confirm safety, performance and clinical benefits of the Zimmer® Plates…
- Conditions
- Proximal Humeral Fracture, Proximal Tibia Fractures, Diaphyseal Fracture
- Trial name
- NCT05215613
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Zimmer Biomet
Diaphyseal Femur Fracture
Comparative Study Between Operative and Non-Operative Management of Femoral Shaft Fractures in Children
The goal of this clinical trial was to compare the management of pediatric femoral shaft fractures using either Thomas splint traction or Elastic Stable Intramedullary Nailing (ESIN).
- Trial name
- ESIN-THOMAS (NCT07483944)
- Testing
- Thomas splint, ESIN (Elastic Stable Intramedullary Nails)
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Fracture, Closed, Comminuted, Healing
Electromagnetic Stimulation as Coadjuvant in the Healing of Diaphyseal Femoral Fractures
This study specifically evaluates the effects of electromagnetic stimulation for diaphyseal femur fractures using a device developed by the investigators.
- Trial name
- NCT02188836
- Testing
- Electromagnetic stimulation
- Where
- Colombia
- Volunteers
- 64 people
- Sponsor
- Fundacion Clinica Valle del Lili
Fracture Healing
Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing
The primary objective of this study is to investigate the effect of romosozumab compared with placebo on time to radiographic healing of fresh tibial diaphyseal fractures (fractures in the midsection of the shinbone).
- Trial name
- STARTT (NCT00907296)
- Testing
- Romosozumab
- Where
- 103 sites in United States, Australia and 21 more
- Volunteers
- 402 people
- Sponsor
- Amgen
Femur Fracture
Skeletal Versus Cutaneous Traction For Treatment of Femur Fractures
The purpose of this study is to determine whether there are any differences in skeletal or cutaneous traction for the treatment of femur fractures.
- Trial name
- NCT00916136
- Testing
- Femoral Traction
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University Medical Center
Pediatric Femur Fracture
Pediatric Femur Fractures: Functional Bracing vs Spica Casting - Outcomes and Cost Analysis
Pediatric diaphyseal femur fractures that occur in children aged 6 months to 5 years old are traditionally treated with hip spica casting.
- Trial name
- NCT06569199
- Testing
- Functional Bracing, Hip Spica Cast
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Calgary
Shaft Femure Fracture in Adolescents
Fixation of Shaft Femure Fracrture by Ender Versus Plate
The aim of this study is to compare the functional outcomes, fracture healing time, rate of complications, and long-term growth outcomes between intramedullary nail and plating in adolescent.
- Trial name
- NCT07067333
- Testing
- intramedullary nails for group A, plate for group B
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Fracture Fixation, Intramedullary, Surgical Wound Infection
Incidence and Risk Factors for Surgical Site Infection After Intramedullary Nailing of Femoral and Tibial Fractures
Diaphyseal femoral and tibial fractures are in the spotlight within the traumatology-orthopedics scenario. Intramedullary nailing (IMN) remains the method of choice for treating these fractures, both open and closed ones.
- Trial name
- NCT03148067
- Testing
- Intramedullary nailing for fracture fixation
- Volunteers
- 225 people
- Sponsor
- University of Sao Paulo
Tibial Fractures
Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing
The primary purpose of this study is to perform a high-quality randomized control trial comparing intramedullary tibial nail fixation with standard design nails to a micromotion tibial nail device, to evaluate the rates of union…
- Trial name
- NCT06679049
- Testing
- micromotion intramedullary nail cohort, standard intramedullary nail cohort
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Tibial Fractures
Study Evaluating InductOs in Diaphyseal Tibia Fractures
Demonstrate a larger proportion of subjects with healed fractures among subjects treated with InductOs and reamed, locked intramedullary nailing compared to subjects treated with reamed, locked intramedullary nailing alone.
- Trial name
- NCT00161616
- Testing
- InductOs
- Where
- 27 sites in Belgium, Finland and 10 more
- Volunteers
- 277 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Humeral Fractures, Multiple Trauma
Plating of Humeral Shaft Fractures in Multiple Trauma Patients.
The purpose of this study is to review our experience with the operative management of acute diaphyseal fractures of the humerus via an anterolateral approach with the use of small fragment fixation at a Level I, urban, trauma…
- Trial name
- HUMERUS (NCT00720681)
- Volunteers
- 96 people
- Sponsor
- OhioHealth
Tibial Fractures
Pulsed Electromagnetic Field (PEMF) Stimulation for Tibia Fractures
Fractures of the tibial shaft (diaphysis) are some of the most common long bone fractures. They most frequently occur in males less than 40 years of age.
- Trial name
- NCT00127725
- Testing
- Pulsed electromagnetic field stimulation
- Where
- 5 sites in Australia
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Sydney South West Area Health Service
Humeral Diaphysis Fracture
Conservative Treatment Versus the Surgical Treatment of Diaphyseal Fractures of Humerus
The fracture of the humeral diaphysis is a condition that represents 2% of all fractures. The conservative treatment of diaphyseal fractures of the humerus has long been considered the only option and the surgical treatment was…
- Trial name
- NCT01116349
- Testing
- Plate and screws or nailing, Hanging Support System (HSS) brace
- Where
- 2 sites in Canada
- Volunteers
- 4 people
- Sponsor
- Hopital de l'Enfant-Jesus
Forearm Injuries, Radius Fractures
Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails
This study looks at children with forearm fractures that need surgery. The standard treatment uses titanium nails, which usually need to be removed in a second operation later.
- Conditions
- Forearm Injuries, Radius Fractures, Ulna Fractures, Fractures, Bone
- Trial name
- FOREST (NCT07536581)
- Testing
- Bioabsorbable intramedullary nail, Titanium elastic intramedullary nail
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Children's Fractures Interest Group, Denmark
Non Union Diaphyseal Fractures
A Randomized Controlled Cost Study of Infuse BMP 2 vs Iliac Crest Autograft for Non Union of Long Bone Fractures
We are inviting individuals such as yourself, who have diaphyseal fracture (broken bone) with a non union to participate in this research study.
- Trial name
- Infuse (NCT00856479)
- Testing
- Infuse Bone Morphogenic Protein (BMP) 2, iliac crest autograft
- Where
- Canada
- Sponsor
- Ross Leighton
Distal Radius Fracture
Retrograde Elastic Nailing With Pollar K-wire in Metaphyseal Diaphyseal Fracture of Distal Radius in Pediatric Patients
Distal radius fractures are the most common fractures in the pediatric population . It accounts for 35% of all pediatric fractures .
- Trial name
- NCT07162142
- Testing
- elastic nailing with pollar K.wire
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Fracture Humerus of Shaft
Scandinavian Humeral Diaphyseal Fracture Trial
This pragmatic multicenter randomized controlled trial (RCT) includes adult participants with an acute humeral shaft fracture to compare surgical fixation of humeral shaft fracture to non-surgical treatment with early…
- Trial name
- SHAFT (NCT04574336)
- Testing
- Surgical treatment, Non-surgical treatment
- Where
- 22 sites in Denmark, Finland and 2 more
- Volunteers
- 287 people
- Sponsor
- Kolding Sygehus