Clinical trials: Diarrhea
Soil-transmitted Helminthiasis, Schistosomiasis
Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders
NIDIAG is an international collaboration on integrated diagnosis-treatment platforms, funded by the European Commission (EC). NIDIAG aims to develop an improved, patient-centred system for delivering primary health care in…
- Conditions
- Soil-transmitted Helminthiasis, Schistosomiasis, Strongyloidiasis, Shigellosis
- Trial name
- NIDIAGDigest (NCT02105714)
- Testing
- Stool culturing for pathogenic bacteria, Kato-Katz technique, Baermann technique
- Where
- 7 sites in Côte d’Ivoire, Indonesia and 2 more
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Gas, Bloating
Assessment and Validation of Electronic Gas and Bloating Diary
The investigator's goal is to improve the patient's compliance and accurate capture of patient reported gas and bloating symptoms, by utilizing a phone application that interactively records each gas and bloating event in…
- Conditions
- Gas, Bloating, Distension, Constipation
- Trial name
- NCT04684849
- Testing
- APP Diary, Paper Diary
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Augusta University
Stool Assessment, Skin Rash
GI Symptoms in Infants Fed Goat Milk-based Infant Formula
A cross-sectional observational survey was conducted in Brazil, Mexico, Russia, and The Netherlands by recruiting parents/legal guardians through social media.
- Conditions
- Stool Assessment, Skin Rash, Urticaria, Regurgitation
- Trial name
- NCT06755424
- Where
- Netherlands
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Neonatal Sepsis, Sepsis
Probiotics for Prevention Neonatal Infection
Neonatal sepsis (serious infection) continues to be one of the major causes of morbidity and mortality in the newborn period around the world.
- Conditions
- Neonatal Sepsis, Sepsis, Neonatal Infections
- Trial name
- NCT01214473
- Testing
- Synbiotics, Maltodextrin
- Where
- 2 sites in India
- Volunteers
- 4,556 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Dysentery, Diarrhoea
Solar Disinfection (SODIS) of Drinking Water for Use in Developing Countries or in Emergency Situations
SODISWATER was a health impact assessment study investigating the effect of sunlight to inactivate microbial pathogens in drinking water.
- Trial name
- SODISWATER (NCT01306383)
- Testing
- SODIS Bottle
- Where
- 3 sites in Cambodia, Kenya and 1 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Malnutrition, Diarrhea
Evaluation of Zinc and / or Micronutrient Supplementation on Intestinal Flora, Diarrheal Disease Burden, Intestinal Mucosal Integrity and Growth Among Children of Pakistan
Information on the mechanisms of zinc is still in developing phase. Ecological and biological implications of long term zinc supplementation at population level requires assessment.
- Conditions
- Malnutrition, Diarrhea, Pneumonia, Growth
- Trial name
- NCT00705445
- Testing
- Micronutrient Supplementation without Zinc, Micronutrient Supplementation with Zinc, Nutritional Counselling and Education
- Where
- 2 sites in Pakistan
- Volunteers
- 2,745 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Diarrhea Infantile
Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China
This study will establish a clinical cohort of children with congenital diarrhea and enteropathy (CODE), mine biomarkers of CODE through multi-omics technology and construct a clinical risk prediction model.
- Trial name
- NCT06356545
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Irritable Bowel Syndrome, Post Infective Bowel Dysfunction
Saccharomyces Cerevisiae CNCM I-3856 Treatment in Irritable Bowel Syndrome With Diarrhea (IBS-D) and Post Infective Bowel Dysfunction
Irritable Bowel Syndrome (IBS) is a common condition characterised by abdominal pain or discomfort and altered bowel habit affecting up to 10% of the population.
- Trial name
- NCT00977587
- Testing
- Saccharomyces Cerevisiae CNCM I-3856
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nottingham
Cholera
Safety and Immunogenicity of a New Formulation of a Bivalent Killed, Whole-Cell Oral Cholera Vaccine
The purpose of this study is to evaluate the safety and immunogenicity of a new formulation of a locally-produced bivalent, (O-1 and O-139) killed whole cell oral cholera vaccine among Vietnamese adults.
- Trial name
- NCT00128011
- Testing
- killed oral cholera vaccine
- Where
- Vietnam
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Viral Gastroenteritis Due to Rotavirus
Optimising Rotavirus Vaccine in Aboriginal Children
Australian Indigenous children, particularly those living in remote communities, suffer a disproportionately high burden of rotavirus gastroenteritis disease.
- Trial name
- ORVAC (NCT02941107)
- Testing
- Rotarix (RV1)
- Where
- Australia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Telethon Kids Institute
Diarrhea
Low-dose Challenge Model With Enterotoxigenic E Coli
This study will validate a model for testing new vaccines designed to protect against intestinal infections with enterotoxigenic Escherichia coli (ETEC).
- Trial name
- NCT00844493
- Testing
- E coli strain H10407 and buffer, E coli H10407 and buffer
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diarrhea, Respiratory Infection
Evaluating the Impact of Community Led Total Sanitation Programs in Mali
Behavioral change is a key ingredient for successful adoption of better sanitation practices in rural Africa. Sanitation programs have, for some time now, incorporated the need to raise awareness and emphasize the benefits of…
- Trial name
- CLTS (NCT01900912)
- Testing
- CLTS
- Where
- Mali
- Volunteers
- 39,246 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de La Plata
Infections, Rotavirus
Vaccine Efficacy Against Rotavirus Diarrhea; Vaccine Given With Routine Childhood Vaccinations in Healthy African Infants
The primary objective of this study is to determine if the GSK Biologicals' human rotavirus (HRV) vaccine (pooled HRV groups) given concomitantly with routine expanded program on immunisation (EPI) vaccinations can prevent severe…
- Trial name
- NCT00241644
- Testing
- Rotarix™
- Where
- 13 sites in Malawi, South Africa
- Volunteers
- 2,089 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Traveler's Diarrhea
Clinical Trial of CBS-2004 in Prevention of Travelers' Diarrhea
This study is designed as a randomized double-blinded treatment trial among travelers' to geographical areas with moderate-severe rates of traveler's diarrhea.
- Trial name
- NCT02736539
- Testing
- CBS 2004 (galacto-oligosaccharides)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Clasado Biosciences Ltd
Pneumonia, Diarrhea, Fever
Treatment of Pneumonia, Diarrhoea and Fever in Children by Community Health Workers
The investigators propose to test the feasibility and acceptability of community health workers (ASHAs and ANMs) being able to treat sick children in the community.
- Trial name
- NCT02623166
- Where
- India
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Antibiotic-associated Diarrhea
The Efficacy of a Probiotic for Antibiotic Associated Gastrointestinal Symptoms
This study evaluates the effect of a multistrain probiotic on gastrointestinal (GI) complaints and diarrhoea in subjects receiving short-term antibiotic (AB) treatment
- Trial name
- PANDA (NCT05845073)
- Testing
- Probiotic
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Waterborne Diseases, Diarrhea
Water Filter Study in Ciudad Victoria
This study measures effects of water filters and filter types on household health in Ciudad Victoria, Mexico.
- Trial name
- NCT06149715
- Testing
- Bottle Filter, Bucket Filter, Tap Filter
- Where
- Mexico
- Volunteers
- 9,887 people, healthy volunteers welcome
- Sponsor
- Aquora Research & Consulting, LLC
Rotavirus Gastroenteritis
Introduction of an Oral Live Human Rotavirus (Rotarix) Vaccine in Matlab
The study will be conducted in the Matlab Health and Demographic Surveillance System (HDSS) field area of the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) to determine the population effectiveness of…
- Trial name
- NCT00737503
- Testing
- Rotavirus Vaccine (ROTARIX)
- Where
- Bangladesh
- Volunteers
- 4,550 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Bowel Movement Regulation, Occasional Constipation
Effect of Bacillus Subtilis DE111® on Daily Bowel Movements
The purpose of this study is to determine the efficacy of Bacillus subtilis DE111® probiotic for regulation of bowel movements.
- Conditions
- Bowel Movement Regulation, Occasional Constipation, Occasional Diarrhea
- Trial name
- NCT04083521
- Testing
- Bacillus subtilis DE111®
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes