Clinical trials: Diarrheal Disease
Diarrhoeal Disease, Respiratory Infection
Water Filters and Improved Cookstoves in Western Rwanda
DelAgua Health Rwanda (Implementation) Ltd. together with Rwanda Ministry of Health (MoH) are delivering an intervention, consisting on the free distribution of one advance water filter and one improved cookstove to all household…
- Conditions
- Diarrhoeal Disease, Respiratory Infection, Pneumonia
- Trial name
- NCT02239250
- Testing
- Water filter and cookstove
- Where
- Rwanda
- Volunteers
- 1,582 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Acute Respiratory Infection, Diarrheal Disease
Efficacy and Tolerance of a Follow-On Formula Fed to Children From 36-48 Months of Age
The purpose is to determine if the consumption of study product has an effect on acute respiratory infections and/or diarrheal disease.
- Trial name
- NCT01488435
- Testing
- Cow's milk, Follow-On Formula
- Where
- China
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Cholera, Diarrhea
Cholera-Hospital-Based-Intervention-for-7-days
The Cholera Hospital Based Intervention for 7 Days (CHoBI7) randomized controlled trial for transition to scale aimed to: (1) Develop and evaluate scalable approaches to integrate the CHoBI7 intervention into the services…
- Conditions
- Cholera, Diarrhea, Stunting
- Trial name
- CHoBI7 (NCT04008134)
- Testing
- CHoBI7 health facility program, CHoBI7 mHealth program, CHoBI7 home visit program
- Volunteers
- 2,626 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diarrhoeal Disease, Prolonged Diarrhea
Green Banana Added Diet on Prolong Diarrhea in 6-59 Months Old Children (GB in ProD)
The study likely to yield improved therapeutic modalities for children with prolonged diarrhea, a sequalae often leads to persistent diarrhea, which is linked to as much as 35% of diarrhea-associated deaths in children <5 years…
- Trial name
- GB in ProD (NCT07848789)
- Testing
- MS, MS +GB
- Where
- Bangladesh
- Volunteers
- 104 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Diarrhoea;Acute, Diarrhea, Infantile
Efficiency and Safety of Zinc Sulphate to Reduce the Duration of Acute Diarrheal Disease Between 6 and 59 Months of Age
This study evaluates the effect of zinc over the duration, severity and relapse of acute diarrheic disease, in children between 6 and 59 months of age.
- Trial name
- ESZnDiarrhea (NCT04061538)
- Testing
- zinc sulfate
- Where
- 9 sites in Mexico
- Volunteers
- 529 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Compliant Behavior, Diarrheal Disease
Rural China Electric Kettle Promotion Program
This study will evaluate the impact of a pilot Rural Electric Kettle Promotion Program offered to low-income households in rural Anhui Province, China.
- Conditions
- Compliant Behavior, Diarrheal Disease, Pollution; Exposure
- Trial name
- NCT03376152
- Testing
- Electric Kettle Promotion
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Cryptosporidium; Diarrhea, Cryptosporidiosis
Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya
The aim of the study is to examine the efficacy of ceramic water filters to reduce the burden of waterborne diarrheal illness among infants in selected villages in Kenya.
- Conditions
- Cryptosporidium; Diarrhea, Cryptosporidiosis, Communicable Diseases, Diarrheal Disease
- Trial name
- NCT01695304
- Testing
- Ceramic water filter
- Where
- Kenya
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Acute Gastroenteritis
Optimizing the Management of Acute Diarrhoeal Disease
Many children admitted to hospital in Botswana without bloody diarrhoea are presumed to have viral gastroenteritis and so not treated with antibiotics - but they may indeed have a treatable cause for their illness.
- Trial name
- NCT02803827
- Testing
- Rapid diagnostics, Probiotic
- Where
- 4 sites in Botswana
- Volunteers
- 276 people
- Sponsor
- Hamilton Health Sciences Corporation
Healthy Volunteer
CampETEC Hyperimmune Bovine Colostrum (HBC)
Gastrointestinal infections cause significant morbidity in the form of acute diarrheal illness in the United States (US) and among travelers to low- and middle-income countries (LMICs).
- Trial name
- NCT06122870
- Testing
- CampETEC HBC product, ProMilk 85, C. jejuni CG8421 Challenge strain
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diarrhea
Impact of Hand Washing and WASH Educational Intervention on Under-five Diarrheal Diseases
The investigators evaluated the impact of water, sanitation and hygiene educational Intervention and hand washing with soap on the incidence of diarrhea among under-five children.
- Trial name
- WASH (NCT02779010)
- Testing
- Hand washing with soap and Health education
- Volunteers
- 1,190 people, healthy volunteers welcome
- Sponsor
- Ethiopian Institute of Water Resources
Irritable Bowel Syndrome
Low FODMAPs Diet vs. Specific Dietary Advice in Patients With IBS Diarrheal Variant
A reduced content of FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) in the diet may be beneficial for patients with IBS diarrheal variant, but so far few randomized trials have reported data…
- Trial name
- DIETSINIBS (NCT03423069)
- Testing
- Diet low in FODMAPs, Specific dietary advice for IBS
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Acute Diarrheal Disease, Acute Respiratory Infection
"Alcohol Based Hand Sanitizers for the Prevention of Acute Diarrheal Disease and Acute Respiratory Infection in Children Under 5 Attending Childcare Centers in Bogotá, Cundinamarca and Tolima, in Colombia: a Cluster Randomized Control Trial"
The purpose of this study is to conduct a Randomized Control Trial (RCT) in a developing country setting in order to evaluate the role of alcohol based hand sanitizers (ABHS) in preventing the transmission of infectious diseases…
- Trial name
- NCT00963391
- Testing
- ABHS use
- Where
- Colombia
- Volunteers
- 1,727 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Anemia
Effect of Soaking Complementary Foods Flour on Hemoglobin Concentration, Anthropometric Deficits and Episode of Diarrheal, Cough and Fever Morbidities
Removing anti nutrient factors using simple cost-effective and sustainable household methods to improve nutritional status of children in communities were plant based complementary foods are the main source of Nutrients is highly…
- Trial name
- NCT05254717
- Testing
- counselling
- Where
- Ethiopia
- Volunteers
- 700 people
- Sponsor
- Madda walabu university
Diarrheal Diseases
Effects of Multiple Interventions on Under-Five Diarrhea
Diarrhea is the leading cause of death, especially in developed nations. Though there are effective interventions, diarrhea remains the leading cause of death among children in Ethiopia
- Trial name
- NCT07158632
- Testing
- handwashing education, water chlorination, combined intervention
- Where
- Ethiopia
- Volunteers
- 835 people
- Sponsor
- Jimma University
Telemedicine, Pediatrics
Improving Nighttime Access to Care and Treatment; Part 4-Haiti
Children in resource-limited settings who develop illness at night are often isolated from care, resulting in progression to an emergency.
- Trial name
- INACT4-H (NCT05480930)
- Testing
- paper-based clinical decision support (dCDS) tool, digital clinical decision support (dCDS) tool
- Where
- Haiti
- Volunteers
- 7,124 people
- Sponsor
- University of Florida
Healthy, Diarrhea
Calcium, Probiotics and Acute Diarrheal Disease Among Indonesian Children
This is a long term study on the efficacy of dietary calcium with or without probiotic strains in reducing the mean number of episodes and duration of diarrheal disease.
- Trial name
- NCT00512824
- Testing
- low calcium milk of 180 ml, regular milk of 180 ml, regular milk of 180 ml + probiotics
- Where
- Indonesia
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Acute Diarrheal Disease, Rotavirus Infection
Two-year Surveillance of Rotavirus Genotypes Causing Acute Diarrhea in Children Younger Than 5 Years Requiring Emergency Room (ER) and Hospital Admission in Chile
The purpose of this study is to prospectively determine the rotavirus VP7/VP4 genotypes associated with moderate to severe disease (requiring emergency room (ER) consult or hospitalization) in a large public hospital from…
- Trial name
- NCT00895492
- Where
- 2 sites in Chile
- Volunteers
- 967 people
- Sponsor
- University of Chile
Antibiotic-Associated Diarrhea, Clostridium Difficile
Efficacy of Loperamide for C. Difficile Colitis and Other Diarrheal Diseases Associated With Antibiotic Therapy
To determine whether symptomatic treatment of the diarrhea in CDAD reduces morbidity and mortality of this serious nosocomial infection in patients who have antibiotic-associated diarrhea. Both C.
- Trial name
- loperamide (NCT00591357)
- Testing
- loperamide
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Diarrhea, Malnutrition
Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development
Malnutrition is considered one of the most prevalent risk factors for morbidity and mortality in children under five. An estimated 20% of children in the developing world are malnourished [1] and poor nutrition is linked to more…
- Conditions
- Diarrhea, Malnutrition, Stunting, Wasting
- Trial name
- MAL-ED (NCT02441426)
- Where
- 8 sites in Bangladesh, Brazil and 6 more
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Foundation for the National Institutes of Health
Dietary Rice Bran Supplementation
Pilot Feasibility of Rice Bran Supplementation in Nicaraguan Children
The purpose is to assess feasibility of rice bran consumption in weaning children and collect pilot data on gut microbiome and metabolome modulation with rice bran intake for diarrheal prevention.
- Trial name
- NCT02615886
- Testing
- Observational Control, Rice bran
- Where
- 2 sites in United States, Nicaragua
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Colorado State University