Clinical trials: Diet, High-Fat
Type 2 Diabetes Mellitus
Effect of Gemigliptin on Metabolic Endotoxemia and Lipemia
This is an exploratory study on the metabolic endotoxemia associated with type 2 diabetes. The investigators will measure systemic endotoxin level and lipid level after ingestion of high fat diet to evaluate the effect of…
- Trial name
- NCT02186080
- Testing
- Gemigliptin
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Cardiovascular Diseases
The Effects of Fat and Theobromine on apoA-I
Rationale: Despite successful efforts to lower atherogenic serum low-density lipoprotein (LDL) cholesterol concentrations, a substantial residual cardiovascular risk is still present.
- Trial name
- NCT02085109
- Testing
- Fat milkshake, Theobromine
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity, Overweight
Effect of Food Temperature and Diet Composition on Satiety, Satiety Hormones, Chewing Time and Neuronal Activity
Obesity and its related illnesses have become serious health issues, obesity is today the fifth most common cause of death. Obesity rate has dramatically enhanced in both male and female, and across all ages.
- Trial name
- NCT05822167
- Testing
- High Protein Meal at Cold Temperature, High Protein Meal at Warm Temperarute, High Protein Meal at Hot Temperature
- Where
- Pakistan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Obesity
High Fat Diet: Oxidative and Cardiovascular Effects
To test the effects of a modified Atkins high fat diet on endothelial function, insulin resistance and energy balance.
- Trial name
- AFN (NCT00696228)
- Testing
- MUFA, PUFA, SFA
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Insulin Resistance, Type2 Diabetes Mellitus
High-fat Overfeeding, Hepatokines and Appetite Regulation
The present study will investigate the effect of high-fat overfeeding on a group of liver-secreted proteins linked to worsened blood sugar control, as well as proteins involved in appetite control.
- Conditions
- Insulin Resistance, Type2 Diabetes Mellitus, Non-Alcoholic Fatty Liver Disease, Obesity
- Trial name
- OVEREAT (NCT03369145)
- Testing
- High-fat diet
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Insulin Sensitivity, Weight
Effect of Low-carbohydrate/High-fat Diet on Glucose Tolerance and Lipid Profile in Lean, Healthy Women
Intervention studying the effect of a low-carbohydrate/high-fat (LCHF) diet as well as on bout of exercise in combination with either a normal diet or a LCHF diet, in relation to glucose metabolism, insulin sensitivity, lipid…
- Trial name
- LCHF (NCT02005224)
- Testing
- LCHF diet and a bout of exercise
- Where
- Norway
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Atlantis Medical University College
Lipedema, Overweight and Obesity
Ketogenic Diet in Women With Lipedema
Lipedema is a chronic fat tissue disorder that usually affects the lower limbs, excluding the feet. Clinical symptoms of lipedema include a noticeable disproportion between the upper and lower body, a tendency to easy bruising…
- Trial name
- NCT07530341
- Testing
- Low carbohydrate high fat (ketogenic) diet with anti-inflammatory properties
- Where
- Poland
- Volunteers
- 121 people
- Sponsor
- Wroclaw Medical University
Anthocyanins
Inflammatory and Metabolic Responses to Long-term Dietary Supplementation With Anthocyanin-rich Blend
This study will investigate the capacity of an anthocyanin-rich blend (ACRB) dietary supplement to improve the alterations in lipid and glucose homeostasis triggered by consumption of a high-fat meal.
- Trial name
- NCT04637945
- Testing
- ACRB
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Cardiovascular Disease, Dyslipidemia
Effects of High Fruit, Vegetable, and Dairy Intake on Plasma Lipids and Blood Pressure in Healthy Individuals
The Dietary Approaches to Stop Hypertension (DASH) trial has been shown to reduce blood pressure and plasma total and LDL-cholesterol (C) compared to a Western diet, but shows no benefit on other blood lipid variables associated…
- Conditions
- Cardiovascular Disease, Dyslipidemia, Blood Pressure
- Trial name
- NCT01404897
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Overweight, Obesity
"Improving Diet, Exercise And Lifestyle (IDEAL) for Women" Study
Diets all share the same principle: eat less energy than you need. This results in weight loss. However, the weight loss is usually a combination of a loss of body fat and muscle mass.
- Trial name
- NCT00710398
- Testing
- Exercise - Aerobic and Resistance, Dietary - Caloric Restriction
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- McMaster University
Type 1 Diabetes, Adolescent
Additional Insulin for High Fat/Protein in Type 1 Diabetes
Aim: Dietary carbohydrate is the predominant macronutrient affecting postprandial blood glucose excursions, dietary fat and protein can also significantly impact the postprandial glycemic profile.
- Trial name
- NCT05152121
- Testing
- Carb and fat counting
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Healthy
A Clinical Trial to Compare The Pharmacokinetics of A Pregabalin GLARS-NF1 Tablet 150mg With Immediate Release Formulation and to Assess The Effect of High Fat Diet in Healthy Male Subjects
The purpose of this clinical trial is to compare the pharmacokinetic characteristics of GLA5PR GLARS tablet 150mg and Lyrica Capsule 75mg. GLA5PR GLARS tablet 150mg is a New Formulation which is made by GL Pharm Tech.
- Trial name
- NCT02326987
- Testing
- Pregabalin 150mg, Pregabalin 75mg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Healthy
A Clinical Trial to Compare The Pharmacokinetics of A Pregabalin GLARS Tablet 150mg With Immediate Release Formulation and to Assess The Effect of High Fat Diet in Healthy Male Subjects
The purpose of this clinical trial is to compare the pharmacokinetic characteristics of GLA5PR GLARS tablet 150mg and Lyrica Capsule 75mg.
- Trial name
- GLA5PR-101 (NCT01635751)
- Testing
- Pregabalin
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Adenocarcinoma of the Prostate, Stage I Prostate Cancer
Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer
This randomized phase II trial will evaluate if a low omega-6, high omega-3 fat diet combined with fish oil has the potential to delay disease progression in patients with prostate cancer undergoing active surveillance.
- Conditions
- Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
- Trial name
- NCT02176902
- Testing
- behavioral dietary intervention, omega-3 fatty acid, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Endocrine and Metabolic Responses to Exercise and Diets
Exercise Effects on Insulin, Gut Peptides, and Appetite
Determine whether the mid-day suppression of hunger and amplified increase in the release of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide 1 (GLP-1) following morning exercise is due to increased fat…
- Trial name
- XFG (NCT01891617)
- Testing
- Exercise and diets
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Insulin Sensitivity, Insulin Resistance
Effect of Yakult Ingestion on Diet-induced Insulin Resistance in Humans
Participants will be randomly allocated to either Yakult ingestion or a control group. For the first 20 days, subjects will consume their normal diet (keeping a detailed food diary throughout).
- Conditions
- Insulin Sensitivity, Insulin Resistance, Type 2 Diabetes Mellitus
- Trial name
- NCT03037918
- Testing
- Yakult light
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Type 2 Diabetes
Diabetes Dietary Study- Low Carbohydrate and Low-Fat Diets in Type 2 Diabetes
The purpose of this study is to determine the effects of a low-carbohydrate diet compared to a low-fat/high-carbohydrate diet on glucose control in patients who have Type 2 Diabetes.
- Trial name
- NCT00795691
- Testing
- low-carbohydrate diet, low-fat diet
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Albert Einstein College of Medicine
Inflammation, Obesity
Impact of a High Saturated Fat Diet on Fasted Systemic and White Adipose Tissue Inflammatory Responses
This study will investigate the effect of a 7-day westernised high-fat (65% of kilocalories), high-calorie (150% of requirements) diet on markers of inflammation in the blood and white adipose tissue.
- Conditions
- Inflammation, Obesity, Inflammatory Response, Cardiovascular Diseases
- Trial name
- NCT03569189
- Testing
- High Fat Diet
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthy Subjects
A Food Effect Study of KC1036 in Healthy Subjects
The primary objective of the study was to assess the effect of High Fat Diet on the pharmacokinetics of KC1036 in Chinese adult healthy subjects.
- Trial name
- NCT05265338
- Testing
- KC1036
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Beijing Konruns Pharmaceutical Co., Ltd.
Bipolar Disorder I, Bipolar II Disorder
Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness
To initiate a low-carbohydrate, high-fat (LCHF) or ketogenic dietary (KD) intervention among a cohort of outpatients with bipolar illness who also have metabolic abnormalities, overweight/obesity, and/or are currently taking…
- Conditions
- Bipolar Disorder I, Bipolar II Disorder, Bipolar I Disorder, Bipolar Disorder
- Trial name
- NCT05705063
- Testing
- LCHF Ketogenic Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University