Clinical trials: Diet, High-Fat, open to volunteers
Metabolic Health, Insulin Sensitivity/Resistance
Defining the Human Insulin Resistance Molecular Network; SIGNATURE
The goal of this intervention study is to learn more about what causes insulin resistance in otherwise healthy adults, and how short-term changes in physical activity or diet may influence it.
- Trial name
- SIGNATURE (NCT07255807)
- Testing
- Physical Inactivity, Hypercaloric High-Fat Diet
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diet, Healthy, Body Weight
Diet-Induced Changes in GEnetic Material
This is a pilot study in 10 men to test the hypothesis that perturbations in substrate flux and the circulating metabolic and pro-inflammatory milieus during a high-fat diet paradigm will modulate DNA methylation of genes in…
- Conditions
- Diet, Healthy, Body Weight, Metabolic Disturbance
- Trial name
- DIG 'EM (NCT06252922)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes
Effects of Whole Fruit on Blood Sugar in People With Type 2 Diabetes
This study will determine the effects of consuming whole fruit on blood sugar control, liver fat, and cardiovascular health in adults with type 2 diabetes who are not treated with insulin.
- Trial name
- FRUIT2 (NCT07376226)
- Testing
- Whole Fruit
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Harvard School of Public Health (HSPH)
Diabete Mellitus, Obesity & Overweight
Comparing Two Low-Carbohydrate Diets With a Standard Diet in Type 2 Diabetes
Type 2 diabetes is often accompanied by high blood triglycerides and excess weight, and diet plays a central role in managing these conditions together.
- Conditions
- Diabete Mellitus, Obesity & Overweight, Hypertriglyceridaemia
- Trial name
- NCT07801378
- Testing
- High-Protein Low-Carbohydrate Diet, High-Fat Low-Carbohydrate Diet, Standard diet
- Volunteers
- 168 people
- Sponsor
- National Nutrition and Food Technology Institute
Prediabetes
Cardiometabolic Effects of Pecan Snacking in Prediabetes
The purpose of this study is to investigate the effects of replacing snacks higher in saturated fats and added sugars with pecans on blood sugar control, heart health and diet quality in individuals with prediabetes.
- Trial name
- NCT07235358
- Testing
- Pecan snacking, Usual diet
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Penn State University
Lepidic-Predominant Lung Adenocarcinoma, Lung Adenocarcinoma
Low-glucose/High-fat Intake Dietary Regimen as a Tool for Empowering Diagnostic Accuracy of 2-[18F]FDG PET/CT in Lepidic-predominant Growth Lung Adenocarcinoma
This study evaluates whether a 7-day ketogenic dietary regimen before 2-[18F]FDG PET/CT can improve the diagnostic accuracy of imaging in adults with suspected or histologically confirmed lepidic-predominant lung adenocarcinoma…
- Trial name
- KETO-FDG Lung (NCT07479095)
- Testing
- Ketogenic diet, 2-[18F]FDG PET/CT
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Non-ischemic Dilated Cardiomyopathy, Heart Failure With Reduced Ejection Fraction
High Fat Diet for Cardiac Metabolic Reprogramming
Heart failure (HF) continues to be a leading cause of morbidity and mortality worldwide, despite advances in treatment. HF is often characterized by an altered metabolism in the heart, where glucose is favored over fatty acids as…
- Trial name
- HF4HF (NCT06747429)
- Testing
- High fat diet, Standard diet
- Where
- 5 sites in France, Italy and 2 more
- Volunteers
- 80 people
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Diet, High-Fat, Circadian Rhythm
Food and Circadian Timing
The goals of this study are to uncover the influence of diet on the human circadian timing system. The protocol is a 46-day (28 outpatient days, 18 inpatient days over two 9 day visits) randomized cross-over study designed to…
- Trial name
- FACT (NCT04743271)
- Testing
- High-Fat Diet, Low-Fat Diet
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University