Clinical trials: Diet, Sodium-Restricted
Hypertension
Attitudes and Understanding of Sodium Claims on Food Labels
Sodium-related claims on food labels should help people find lower sodium food choices; however consumer attitudes and understanding of such claims are unknown.
- Trial name
- NCT01764724
- Testing
- Mock package questionnaire
- Where
- Canada
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hemodialysis Patients
Dietary Sodium Restriction in Hemodialysis Patients
Excess dietary sodium can lead to poor outcomes, such as hypertension, edema and increased risk for cardiovascular diseases. These complications are associated with end stage renal disease (ESRD) progression and mortality in…
- Trial name
- NCT01896882
- Testing
- Sodium restriction
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension
Effect of High and Low Sodium Diets on Blood Pressure in Hypertensive Patients Treated With Aliskiren
This study will compare the effects of high and low level sodium (salt) diets on blood pressure in patients with hypertension (high blood pressure) who are taking aliskiren 300 mg.
- Trial name
- NCT00441064
- Testing
- Aliskiren
- Where
- 19 sites in United States
- Volunteers
- 132 people
- Sponsor
- Novartis
Prehypertension, Hypertension
Combined Dietary Education of Low Sodium and High Potassium Consumption
Reduction in sodium consumption is important approach in public health care. In general population, reduction of sodium intake can reduce the future development of hypertension and cardiovascular event.
- Trial name
- NCT01914224
- Testing
- dietary education of low sodium and high potassium consumption, dietary education of low sodium consumption only
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DongGuk University
Hypertension
Mechanisms of Refractory Hypertension (High and Low Salt Diet)
The purpose of the study is to test the hypothesis that persistent fluid retention and high sympathetic output contributes to the development of refractory hypertension (HTN).
- Trial name
- NCT02357017
- Testing
- NaCl tablets
- Sponsor
- University of Alabama at Birmingham
ESRD
Sodium-restricted Diets and Symptoms in End Stage Renal Disease: An RCT
Dietary sodium intake independently increases the risk of mortality in end stage renal disease (ESRD). It plays a significant role in hypertension, hypervolemia, and left ventricular hypertrophy (LVH), and blunts the…
- Trial name
- NCT02778516
- Testing
- Sodium Restriction
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Heart Failure, Dietary Sodium Intake
Effects of Low-Sodium Salt on Death, HF Hospitalization/ Emergency Department Visits and Quality of Life in HF Patients
This study aims to investigate whether using a low-sodium substitute salt can help improve outcomes for patients with heart failure.
- Trial name
- RESCUE-HF (NCT06764225)
- Testing
- low-sodium substitute salt
- Where
- China
- Volunteers
- 1,301 people
- Sponsor
- Heart Health Research Center
Heart Failure
SODIUM-HF: Study of Dietary Intervention Under 100 MMOL in Heart Failure
SODIUM-HF is a multicenter clinical trial in ambulatory patients with chronic HF to evaluate the efficacy of a low sodium containing diet on a composite clinical outcome composed of of all-cause mortality, cardiovascular…
- Trial name
- SODIUM-HF (NCT02012179)
- Testing
- Low sodium diet
- Where
- 26 sites in Australia, Canada and 3 more
- Volunteers
- 806 people
- Sponsor
- University of Alberta
Psoriasis Vulgaris
Low-Salt Diet Effect on Th17-Mediated Inflammation and Vascular Reactivity in Psoriasis
Psoriasis presents an independent cardiovascular risk factor characterized by chronic low-grade systemic inflammation and oxidative stress which altogether might lead to endothelial dysfunction.
- Trial name
- NCT05892640
- Testing
- Low-Salt Diet
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Hypertension, Cardiovascular Diseases
South Asian Low-sodium Trial
The overall goal of this pilot study is to examine the feasibility and acceptability of a culturally-tailored low-sodium dietary intervention is South Asian Canadians with stage one HTN.
- Trial name
- SALT (NCT05136911)
- Testing
- SALT-Intervention
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of Toronto
Obstructive Sleep Apnea
Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea
This study evaluates the intervention of the 1) sodium-restricted diet, or 2) diuretic, or 3) placebo pill in the treatment of obstructive sleep apnea in adults.
- Trial name
- DESALT (NCT01945801)
- Testing
- Lasilactone, Sodium-Restricted Diet
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Heart Failure, Salt; Edema
Sodium Intake in Failing Heart Patients.
Patients with heart failure (HF) have an amelioration in clinical outcomes during a restricted dietary salt intake. To date, they experienced an amelioration of functional New York Association Heart (NYHA) class, reduction of…
- Trial name
- NCT03998891
- Testing
- restricted dietary salt intake
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Campania Luigi Vanvitelli
Hypertension,Essential
The Significance of Sodium Balance and the Value of Salt-blood Test in Identifying Salt Sensitive Patients
This is a randomized controlled trial with 72 patients with hypertension examining the effects on blood pressure of sodium restriction and whether the blood analysis Salt-blood test is associated to a decrease in blood pressure.
- Trial name
- VASA (NCT05165823)
- Testing
- Sodium restriction
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Regional Hospital Holstebro
Diet, Sodium-Restricted, Heart Failure, Systolic
Effect of Sodium Intake on Brain Natriuretic Peptide Levels in Patients With Heart Failure
The SODA-HF trial is a randomized, double-blind, controlled trial to evaluate the effect of moderate to severe sodium restriction on brain natriuretic peptide in patients with heart failure and reduced ejection fraction (less…
- Conditions
- Diet, Sodium-Restricted, Heart Failure, Systolic, Natriuretic Peptide, Brain, Clinical Trial
- Trial name
- SODA-HF (NCT03351283)
- Testing
- Severe sodium restriction, Moderate sodium restriction
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Instituto Mexicano del Seguro Social
Autoimmune Diseases, Asthma
Is a Diet Necessary When Corticosteroid Treatment is Prescribed?
Few recommendations concerning the diet and dosage to be administered to patients treated with corticosteroids are established. It therefore seems important to study prospectively the indication of a diet low in salt and sugar in…
- Trial name
- Cortisel (NCT01420133)
- Testing
- Regimen, Standard regimen
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Disease
Low Sodium Cooking Study
The purpose of this study is to evaluate the acceptance of a salt restricted diet cooked with a controlled amount of salt in patients with heart disease.
- Trial name
- NCT03481322
- Testing
- Cooked diet with controlled amount of salt
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Arterial Hypertension, Sodium Urine
TO ASSESS THE EFFECTIVENESS OF THE INTERVENTION OF THE LOW-SODIUM DIET IN PATIENTS WITH HTA
Arterial hypertension is an independent vascular risk factor and a frequent reason for consultation in Primary Care. It generates high cardiovascular morbidity and mortality (stroke, heart disease, kidney failure and other…
- Conditions
- Arterial Hypertension, Sodium Urine, Primary Care Center, Diet Habit
- Trial name
- IDI-HTA2020 (NCT04677322)
- Testing
- Adult patients diagnosed and treated for high blood pressure
- Where
- Spain
- Volunteers
- 2 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Blood Pressure, Hypertension
A Community Health Worker-Led LSSS Intervention in Bangladesh
The sodium found in salt is a powerful cause of high blood pressure, and most sodium ingested by humans is from their diet. High blood pressure is known to cause heart attacks and strokes, so various public health programs have…
- Trial name
- NCT05425030
- Testing
- Low-Sodium Salt Substitute, Information/Education
- Where
- Bangladesh
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Stanford University
Oligohydramnios
Low Sodium Diet in Oligohydramnios Assigned for Conservative Management
The investigators want to examine whether low salt diet can increase the amniotic fluid index in patients diagnosed with oligohydramnios and assigned for conservative management. A randomized controlled trial
- Trial name
- NCT03815968
- Testing
- low sodium diet
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Hypertension,
Serum Levels of Advanced Glycation End-products After Dietary Intervention in Hypertensive Patients
Cardiovascular disease (CVD) is considered the main cause of mortality in the western world. There are many factors that contribute to the onset and progression of cardiovascular disease, including hypertension.
- Trial name
- NCT02848677
- Testing
- Nutritional counseling, usual care
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre