Clinical trials: Diet, Sodium-Restricted
Healthy
Effects of Sodium Intake on (PK/PD) Relationship of a Single Dose of a Renin Angiotensin System-Blocker
The impact of sodium intake on plasma drug concentrations has previously been reported in the literature for verapamil and quinidine but, to the investigators' knowledge, never with renin-angiotensin system blockers such as AT1R…
- Trial name
- NCT00310778
- Testing
- high sodium diet, low sodium diet, ramipril 10 mg
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension,
Educational Intervention for Sodium Restriction in Patients With Hypertension
This parallel, randomized clinical trial will include 120 participants. They will be allocated to a sodium restriction educational intervention or usual care groups.
- Trial name
- NCT02848690
- Testing
- Educational Intervention, Usual Care Intervention Group
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Heart Failure
Estimated Echocardiographic Pulmonary Capillary Wedge Pressure in Heart Failure
The aim of the study was to verify the effects of moderate versus low sodium intake on pulmonary capillary wedge pressure (PCWP), determined by Doppler echocardiography and tissue Doppler imaging in patients suffering from…
- Trial name
- NCT01738659
- Testing
- normal sodium diet
- Volunteers
- 143 people
- Sponsor
- University of Palermo
Heart Failure
Low Sodium vs. Regular Diet in Patients Admitted for Heart Failure
Patients over 18 years of age, admitted to the hospital with HF exacerbation, will be eligible for randomization to low salt or regular diet.
- Trial name
- SALT (NCT02689635)
- Testing
- Sodium Restricted Diet, Regular Diet
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Maya Guglin
Cardiovascular Diseases, Obesity
Low Sodium Diet and Behavioral Intervention for Reversing Arterial Stiffening in Overweight Individuals
Obese individuals are at risk for developing cardiovascular disease (CVD). Increasing physical activity, losing weight, and reducing sodium intake may reverse arterial stiffness and blood vessel damage that is linked to obesity.
- Trial name
- SAVE (NCT00366990)
- Testing
- Low Sodium Diet, Regular Sodium Intake
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diastolic Dysfunction
Effect of Dietary Sodium Restriction in the Management of Patients With Heart Failure and Diastolic Dysfunction
Although half of the patients with HF has normal ejection fraction or slightly altered (HF-PEF) and the prognosis differs little from those with reduced ejection fraction, the pathophysiology of HF-PEF is still poorly understood.
- Trial name
- NCT01896908
- Testing
- Sodium restriction
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension, Cardiovascular Diseases
China Salt Substitute Study
Cardiovascular disease is a leading cause of death and disability worldwide, and blood pressure is a leading determinant of this risk.
- Trial name
- NCT00145756
- Testing
- low sodium high potassium salt substitute
- Where
- 6 sites in China
- Volunteers
- 600 people
- Sponsor
- The George Institute
Heart Failure
The Salt Study for Heart Failure
The purpose of this study is to understand if low sodium (cardiac) diet is indeed necessary for better health outcomes in patients who suffered heart failure.
- Trial name
- NCT07560592
- Testing
- Normal Salt Diet, Cardiac Diet
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Maya Guglin, MD
Heart Failure
Study of Dietary Intervention Under 100 MMOL in Heart Failure
This study aims to identify the relationship between a low-sodium diet and neurohormonal and clinical status in stable chronic HF patients.
- Trial name
- SODIUM-HF (NCT01480401)
- Testing
- low-sodium diet (1500 mg daily)
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Hypertension
Examining the Individual Response to a Restricted Sodium Diet in Hypertensive Patients
Excessive dietary sodium intake is an independent risk factor for hypertension and cardiovascular disease. A vast array of efforts have tried to reduce sodium consumption based on evidence indicating a public health benefit.
- Trial name
- NCT04764253
- Testing
- Modified Sodium Watcher Program + Digital Self-Monitoring, Usual care + Digital Self-Monitoring
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sodium Excess, Cardiovascular Risk Factor
A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor
This study will evaluate the effect of a short, animated storytelling intervention video on sodium intake as a major risk factor for cardiovascular disease on immediate and medium-term retention of knowledge about the risks of…
- Conditions
- Sodium Excess, Cardiovascular Risk Factor, Education Entertainment Intervention, Short, Animated Storytelling
- Trial name
- NCT05735457
- Testing
- A short, animated storytelling video on dietary sodium
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Hypertension, Body Weight
Increasing Calcium Dietary Intake Helps to Control Blood Presure and Body Weight
Mediterranean diet is relatively poor in calcium (about 700 mg/daily) whilst there are several reports indicating beneficial effects of calcium-rich diets.
- Trial name
- NCT02295852
- Testing
- LOW-SODIUM LOW LIPID CALCIUM RICH DIET, LOW-SODIUM LOW LIPID DIET
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Federico II University
Hypertension, Hypertension With Abnormal Renal Function
A Pilot Trial of Manlikang in Reducing Salt Intake and Blood Pressure Among Patients With Hypertension
This study is a single arm trial with before-after comparison design. Three groups of patients with hypertension will be recruited: not taking antihypertension drugs and having normal renal function, taking antihypertension drugs…
- Trial name
- NCT03226327
- Testing
- formula salt with very low sodium (Brand name: Manlikang)
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Peking University
Hypertensive Disease
Activating Media for Salt Reduction
Mass media plays more and more important role in health education, especially in some chronic diseases which related closely with the behavior and habits.
- Trial name
- NCT03074851
- Testing
- low sodium salt, informational intervention
- Where
- China
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- The George Institute for Global Health, China
Healthy
Sodium Diet Effect on Aldosterone and Urinary RNA (SALTY)
This cross-over clinical trial is being conducted to evaluate the difference in urinary messenger RNA (mRNA) biomarkers of mineralocorticoid receptor activation following a low-sodium diet, as compared to a high-sodium diet.
- Trial name
- SALTY (NCT04168073)
- Testing
- High-sodium diet 300 mmol sodium/day, Low-sodium diet 10 mmol sodium/day
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Cluster Headache
Efficacy, Safety and Tolerability of Low Sodium Oxybate for Nocturnal Cluster Headache Attacks
The goal of this clinical trial is to evaluate the efficacy of low sodium oxybate (LXB) (brand name Xywav) in the treatment of (nocturnal) cluster headache attacks in subjects with chronic cluster headache.
- Trial name
- SUNCET (NCT06950281)
- Testing
- Low Sodium Oxybate
- Volunteers
- 52 people
- Sponsor
- Leiden University Medical Center
Declination of Glomerular Infiltration Rate in Chronic Kidney Disease Population
Effect of Intensive Low Sodium Restriction on Glomerular Infiltration Rate in Chronic Kidney Disease
Introduction : Due to Chronic kidney disease is a public health problem, which is important increased in both developed and developing countries .
- Trial name
- NCT02519894
- Testing
- Dietary Scanning Calculator
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- PANTHITA SORNHIRAN
Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)
The Effect of Low Sodium Diet on Idiopathic Hyperaldosteronism
This study was a single-center randomized controlled trial which lasted 14 days and consisted of two stages (run-in period (stage I) and intervention period (stage II) each contain 7 days without potassium supplement.
- Trial name
- NCT05649631
- Testing
- Sodium
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Heart Failure, Edema
Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure
The primary objective of this study is to learn whether a morning dose of extended-release torsemide enhances renal sodium excretion after lunch (4-8 hours after dosing) compared to immediate-release torsemide.
- Conditions
- Heart Failure, Edema, Pulmonary Congestion, Fluid Overload
- Trial name
- NEXT-HF (NCT06995144)
- Testing
- Extended Release Torsemide Tablets, Immedate Release Torsemide Tablets
- Where
- United States
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Idiopathic Hypersomnia, POTS - Postural Orthostatic Tachycardia Syndrome
Effect of Low Sodium Oxybate (LXB) on Autonomic Symptom Burden in Idiopathic Hypersomnia Patients With Postural Tachycardia Syndrome
The investigators hope to learn if low sodium oxybate (LXB) is an effective treatment for symptoms of idiopathic hypersomnia (IH) and postural tachycardia syndrome (POTS).
- Trial name
- NCT07077278
- Testing
- Low sodium oxybate (LXB)
- Volunteers
- 25 people
- Sponsor
- Stanford University