Clinical trials: Diet Interventions
Obesity, Childhood, Asthma in Children
Asthma and Obesity Diet Versus Exercise
Obesity is recognized as a pro-inflammatory condition associated with multiple chronic diseases, including asthma. The specific mechanisms linking asthma and obesity remain hypothetical.
- Conditions
- Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome
- Trial name
- NCT03644355
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Hypertension,
Educational Intervention for Sodium Restriction in Patients With Hypertension
This parallel, randomized clinical trial will include 120 participants. They will be allocated to a sodium restriction educational intervention or usual care groups.
- Trial name
- NCT02848690
- Testing
- Educational Intervention, Usual Care Intervention Group
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Alzheimer Disease, Mild Cognitive Impairment (MCI)
Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
This early phase, open label, single arm clinical trial will determine the intraindividual safety, tolerability and effects of NPC1 (parthenolide and ipriflavone) on blood-based biomarkers of Alzheimer's disease (AD) pathology…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
- Trial name
- NPC1-AD (NCT07236190)
- Testing
- natural product combination-1 (NPC1)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Physical Activity, Diet
Evaluation of the "Americans in Motion - Healthy Interventions" Project
This research project brings together the American Academy of Family Physicians (AAFP) National Research Network (AAFP-NRN) and the AAFP's public health initiative, Americans In Motion (AIM).
- Conditions
- Physical Activity, Diet, Mental Health
- Trial name
- AIM-HI (NCT00534482)
- Testing
- Enhanced Office, Conventional Office, AIM-HI program with enhanced feedback
- Where
- United States
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- American Academy of Family Physicians
Inflammation
Effect of Selenium Intervention on Inflammation in Older Adults
Serum levels of inflammatory mediators increase with age and are strongly associated with the most common and the most devastating health conditions found in older adults including frailty, chronic disease, disability and…
- Trial name
- NCT01289925
- Testing
- Selenium
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity, Appetite Disorders
Impact of a Satiating Diet in Obese Men With a Low Satiety Phenotype
The global research project was organized as a clinical process starting with an evaluation aiming at the determination of a diagnosis pertaining to the degree of satiety signal capacity.
- Trial name
- NCT03128697
- Testing
- Satiating diet, Control diet
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity
Effect of a Synbiotic Supplement on a High-protein Diet
The objective of the trial is to study how a synbiotic treatment will affect weight loss and management in individuals enrolled in weight loss diet Profile®.
- Trial name
- NCT03123510
- Testing
- Bifidobacterium spp plus bimuno- galacto-oligosaccharides
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Diet Modification
A Home-based Intervention to Improve the Diet Quality of Preschoolers
U.S. children eat too little fruits and vegetables and whole grains, and too many energy dense foods, dietary behaviors associated with increased morbidity from cardiovascular diseases.
- Trial name
- NCT03923491
- Testing
- Healthy Feeding, Healthy Eating, Reading Readiness
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Diet, Healthy, Food Selection
Increased Proportion of Lower Energy Density Items vs. Nutritional Labelling at an Online Supermarket
This study will be a 2x2 randomised controlled trial with information-based intervention (no labelling / labelling) and structural intervention (default proportion / increased proportion of lower energy density food items) as…
- Trial name
- NCT04340791
- Testing
- Increased proportion of lower energy density items, Labelling
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Microbiome, Human, Gastrointestinal Tract
Diet and Microbiome Longitudinal Monitoring With Food Intervention
The main goal of this project is to identify the microbiome components change in abundance in response to food ingested including provided foods.
- Trial name
- NCT04758715
- Testing
- Food provided from a commercial meal service provider for a week
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Diet Therapy
Mediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy Adults
Background: Trillions of tiny organisms-including bacteria, fungi, and viruses-live inside our intestines. These microorganisms break down nutrients in our food, aid our immunity, and help keep us healthy.
- Trial name
- NCT05411120
- Testing
- Western Diet, CLEAN-MED
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Hypertension
Delivering a Digital Health Intervention to Improve Food Access and Dietary Quality Among Adults With Hypertension
A total of 65 participants with hypertension and low access to high quality food will be enrolled to test the feasibility of using commercially available grocery delivery services, simultaneous to a robust behavioral…
- Trial name
- NCT06743191
- Testing
- Access Nourish
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Johns Hopkins University
Rheumatoid Arthritis
A Nutrition Intervention for Arthritis -3 (WCCR-ARTH3)
The purpose of the study is to assess whether, in individuals with rheumatoid arthritis, a low-fat, vegan diet improves pain and other subjective symptoms more effectively than a control supplement or a placebo.
- Trial name
- NCT03417648
- Testing
- Plant-based diet, Supplement
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Physicians Committee for Responsible Medicine
Inflammation, Diet Modification
Watermelon Focused Dietary Inflammatory Index Intervention
A large, persuasive, and ever-increasing body of evidence links chronic inflammation to virtually all of the chronic diseases that cause the majority of disability and death in the U.S., including diabetes, cardiovascular…
- Trial name
- IMAGINE (NCT03158740)
- Testing
- DII-Based Counseling System, general health education control
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Michael D. Wirth
Psoriatic Arthritis
Diet Interventions in Psoriatic Arthritis
The purpose of this study is to learn whether changing diet impacts psoriatic arthritis (PsA).
- Trial name
- DIPSA (NCT04180904)
- Testing
- Diet 1, Diet 2
- Where
- 2 sites in United States, Canada
- Volunteers
- 92 people
- Sponsor
- University of Pennsylvania
Chronic Kidney Disease
Reduced Calorie Diet Intervention in Kidney Transplant Recipients
The purpose of this study is to measure the effect of a reduced calorie diet intervention in new kidney transplant recipients on the outcomes weight gain, oxidative stress, and insulin resistance.
- Trial name
- NCT00994838
- Testing
- reduced calorie diet
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Vanderbilt University
Colorectal Cancer
Vitamin D Intervention and Associated Changes in the Gut Microbiome and Vitamin D Levels in Healthy Adults
Although dietary vitamin D supplementation has been used in the clinical setting for decades, the effect of supplementary vitamin D consumption on the structure of the microbiome has not been studied in humans in fine scale or…
- Trial name
- VDMT (NCT05387876)
- Testing
- Vitamin D intervention
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Baylor University
Heart Failure
The Effect of Action Control Based Intervention on Adherence After Cardiac Rehabilitaiton
This will be a pilot study of the effect of an Action Control-based intervention (ACBI) on adherence to prescribed diet and exercise programs after cardaic rehabilitation. The purposes of this study are to: 1.
- Trial name
- NCT00602485
- Testing
- Action Control Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Summa Health System
Diabetes Mellitus, Type 1
Can Gluten-free Diet Prevent the Destruction of Beta-cells During Remission?
Type 1 diabetes (T1D) emerge when the auto-immune destruction exceeds the beta cell's regenerative capacity. The patients' beta-cell capacity increases shortly after onset when glucotoxicity decreases after the start of insulin…
- Trial name
- NCT02284815
- Testing
- Glutenfree diet
- Volunteers
- 20 people
- Sponsor
- Herlev Hospital
Psoriasis
Efficacy Study of Dietary Intervention and Weight Loss in Improving Psoriasis
This is a multicenter randomized controlled clinical trial evaluating the impact of a structured non pharmacological intervention consisting in intensive weight reduction (qualitative and quantitative changes in diet associated…
- Trial name
- NCT01714284
- Testing
- Informative, Diet and Exercise
- Where
- 11 sites in Italy
- Volunteers
- 303 people
- Sponsor
- Centro Studi Gised