Clinical trials: Dietary Carbohydrates
Hyperlipidemia
A Randomized, Double-Blinded Study of Simvastatin 20 mg/Day Versus Vytorin 10/20 in Subjects With Lipid Profiles Not Meeting Current NCEP Guidelines, Following a Low-Carbohydrate Diet
People who follow a low-carbohydrate diet typically experience a decrease in triglycerides and increase in HDL-C level, but fail to lower their LDL cholesterol (LDL-C). Such patients may require lipid-lowering therapy.
- Trial name
- LOCUST (NCT00566267)
- Testing
- simvastatin 20 mg/ezetimibe
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
PreDiabetes, Obesity
Development of an Adaptive Treatment for Weight Loss in People With Prediabetes
This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which combination and sequence of weight loss program features are most effective in people who are…
- Trial name
- NCT04745572
- Testing
- High Carbohydrate Diet, Reduced Carbohydrate Diet
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cancer
Ketogenic Diet in Advanced Cancer
The purpose of this study is to determine the safety and tolerability of a modified low carbohydrate diet, determine if quality of life is improved and to determine if the diet has any effect on tumor growth (size or spread) and…
- Trial name
- NCT01716468
- Testing
- Ketogenic Diet
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Pittsburgh Healthcare System
Ischemic Heart Disease
Does the Advice to Eat a Mediterranean Diet With Low Carbohydrate Intake, Compared With a Low-fat Diet, Reduce Diabetes and Cardiovascular Disease?
This is a multi-centre, open, randomised study in patients treated for ischemic heart disease in Linköping, Norrköping and Jönköping hospitals.
- Trial name
- NCT02938832
- Testing
- Advice on what food to choose and eat
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Linkoeping
Obesity, Anxiety
Effect of rTMS in Combination With a Low-carbohydrate Diet in Patients With Obesity
In the present study the investigators want to evaluate if the application of rTMS can reduce the anxiety and craving in patients with obesity helping them to follow a low carb-diet, as well as, to assess the changes in weight…
- Trial name
- NCT03345368
- Testing
- rTMS, Diet
- Where
- Mexico
- Volunteers
- 49 people
- Sponsor
- Hospital General Ajusco Medio
Type 2 Diabetes
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise
This study will look at how much CagriSema helps participants with type 2 diabetes lower their blood sugar and body weight. CagriSema is a new investigational medicine. Doctors may not yet prescribe CagriSema.
- Trial name
- REIMAGINE 1 (NCT06323174)
- Testing
- Cagrilintide, Semaglutide
- Where
- 50 sites in United States, China and 5 more
- Volunteers
- 189 people
- Sponsor
- Novo Nordisk A/S
Healthy
Added Sugar Intake, Sweet Taste Phenotypes and Biomarkers
The goals of this cross-sectional study on a racially diverse group of children (3-10y) and their mothers are to determine whether the relationship between sweet taste phenotypes differed among mother-daughter and mother-son…
- Trial name
- SWBIO (NCT05047588)
- Where
- United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Obesity, Overweight
Effect of Food Temperature and Diet Composition on Satiety, Satiety Hormones, Chewing Time and Neuronal Activity
Obesity and its related illnesses have become serious health issues, obesity is today the fifth most common cause of death. Obesity rate has dramatically enhanced in both male and female, and across all ages.
- Trial name
- NCT05822167
- Testing
- High Protein Meal at Cold Temperature, High Protein Meal at Warm Temperarute, High Protein Meal at Hot Temperature
- Where
- Pakistan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Type 2 Diabetes (T2DM)
The Effect of OptiFibre Dietary Fiber on Carbohydrate Metabolism and Intestinal Microbiota Metabolism in Patients With Type 2 Diabetes Mellitus
The goal of this clinical trial is to to study the effect of Optifiber PHGG on carbohydrate metabolism in patients with type 2 diabetes mellitus. The main questions it aims to answer are: 1.
- Trial name
- NCT07609992
- Testing
- Nestle Optifibre
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Pirogov Russian National Research Medical University
Irritable Bowel Syndrome
Low FODMAP Diet in Patients With IBS
The aim was aimed to investigate if all carbohydrate groups eliminated in the Low FODMAP diet are equally important in relieving gastrointestinal symptoms in IBS.
- Trial name
- NCT05618106
- Testing
- Low FODMAP DIET = Diet with Low polyol, FOS and GOS
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- Jens Rikardt Andersen
Insulin Sensitivity, Weight
Effect of Low-carbohydrate/High-fat Diet on Glucose Tolerance and Lipid Profile in Lean, Healthy Women
Intervention studying the effect of a low-carbohydrate/high-fat (LCHF) diet as well as on bout of exercise in combination with either a normal diet or a LCHF diet, in relation to glucose metabolism, insulin sensitivity, lipid…
- Trial name
- LCHF (NCT02005224)
- Testing
- LCHF diet and a bout of exercise
- Where
- Norway
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Atlantis Medical University College
Dyslipidemia
Dietary Carbohydrate Type and Cardiovascular Disease (CVD) Risk Indicators
The aim of this study is to determine the effect of habituation to diets with different types of carbohydrate (simple-carb, refined-carb, unrefined-carb) on selected Cardiovascular Disease (CVD) risk indicators.
- Trial name
- NCT01610661
- Testing
- Diet
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tufts University
Lipedema, Overweight and Obesity
Ketogenic Diet in Women With Lipedema
Lipedema is a chronic fat tissue disorder that usually affects the lower limbs, excluding the feet. Clinical symptoms of lipedema include a noticeable disproportion between the upper and lower body, a tendency to easy bruising…
- Trial name
- NCT07530341
- Testing
- Low carbohydrate high fat (ketogenic) diet with anti-inflammatory properties
- Where
- Poland
- Volunteers
- 121 people
- Sponsor
- Wroclaw Medical University
Type 2 Diabetes Mellitus, Overweight
Lifestyle Modification for Obesity-Related Type 2 Diabetes
Dietary carbohydrate is the major determinant of postprandial glucose levels, and preliminary evidence suggests that low carbohydrate diets improve glycemic control when accompanied by weight loss.
- Conditions
- Type 2 Diabetes Mellitus, Overweight, Obesity
- Trial name
- NCT00415688
- Testing
- Low carbohydrate, ketogenic diet, Low glycemic index, reduced calorie diet
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Robert C. Atkins Foundation
Prostate Cancer
Atkins Diet and Prostate Cancer Clinical Trial
This study will test the hypothesis that a low-carbohydrate Atkins diet will prevent or at least minimize the metabolic consequences of androgen deprivation therapy (ADT).
- Trial name
- NCT00932672
- Testing
- Atkins Diet
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Duke University
Childhood Obesity
Role of Carbohydrate Modification in Weight Management Among Obese Children
The purpose of this study is to test the hypothesis that a low-carbohydrate diet and a low-glycemic load diet will improve body mass index and result in more body fat loss than a control diet among overweight children ages 7 to…
- Trial name
- NCT00215111
- Testing
- Low carbohydrate, reduced glycemic load, and a control diet
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity
Mechanisms Underlying Postoperative Insulin Resistance and Inflammation
Having an operation places an enormous burden on the body, leading to the development of inflammation and so called 'insulin resistance'.
- Trial name
- NCT01470534
- Testing
- carbohydrate drink, Muscle biopsy, Blood sampling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Nottingham
Polycystic Ovary Syndrome (PCOS)
Low-Carb Versus Mediterranean Diet in PCOS
This is a randomized controlled trial of two diets (low-carbohydrate and Mediterranean diet) in the treatment of women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05272657
- Testing
- low-carbohydrate diet, Mediterranean diet
- Volunteers
- 130 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Diet, Healthy
Understanding Food Choices in Saudi Arabia- Taxes
Using a 3-arm randomized controlled trial, the investigators aim to rigorously evaluate the effects of two different taxation policies on diet quality.
- Trial name
- NCT05429528
- Testing
- Implicit Tax, Explicit Tiered Tax
- Where
- Singapore
- Volunteers
- 2,490 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Adiposity
Dietary Carbohydrate and Internal Body Fat
This is a 2-year randomized controlled trial to test the effect of dietary carbohydrates, both quality and quantity, on changes in internal body fat mass.
- Trial name
- CARBFUNC (NCT03401970)
- Testing
- Acellular carbohydrate diet, Cellular carbohydrate diet, Low-carbohydrate high-fat diet
- Where
- Norway
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital