Clinical trials: Dietary Carbohydrates
Type 2 Diabetes
Metabolic Response to 3-day Fast Versus Carbohydrate-free Diet in Type 2 Diabetes
The investigators hypothesis is that a carbohydrate-free diet, ingested for 3 days, results in a change in blood glucose that is similar to the change observed after 3 days of fasting.
- Trial name
- CHO-free diet (NCT01469104)
- Testing
- 3 day fast, 3 day CHO-free diet
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Prediabetes
Effects of a Mediterranean Diet With Sequential Cycling and Rowing Exercise on Blood Sugar in Women With Prediabetes or Prediabetes Remission
The goal of this clinical trial is to learn how a Mediterranean-style diet, with and without added exercise, affects blood sugar control in women with prediabetes.
- Trial name
- NCT07326891
- Testing
- Mediterranean Diet, Supervised Sequential Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Begüm Yücesoy Güneysu
Carbohydrate Intolerance
Impact of Two Dietary Interventions on Simple Carbohydrate Intolerance
In this project we want to assess impact of dietary fructose as a simple sugar intolerance on abdominal pain and compare a low FODMAP diet versus an added sugar elimination diet effectiveness on symptoms but also impact on…
- Trial name
- NCT06057376
- Testing
- Low-FODMAP diet group (LFD), Low Sugar diet group (LAS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Diabetes Mellitus, Type 1
The Impact of a Moderate Carbohydrate Diet in Children With Type 1 Diabetes on Hybrid Closed-loop Therapy
In the past, carbohydrate restriction was indicated as a treatment for people with type 1 diabetes when exogenous insulin was not available.
- Trial name
- COMBINE1 (NCT06567158)
- Testing
- Moderate carbohydrate diet, Traditional diet
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Type 1 Diabetes
Low cArbohydraTe dIeT and aUtomated Insulin Delivery System for Type 1 DiabetEs
This is a randomized, controlled study in people living with type 1 diabetes using an automated insulin delivery (AID) system. Participants will be assigned to a control diet (45% carbohydrate) or a low carb diet (25%…
- Trial name
- LATITUDE (NCT05449678)
- Testing
- Low-carb diet
- Volunteers
- 38 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Gestational Diabetes
The Effect of a Low Glycemic Index Diet on Blood Sugar Control in Women With Gestational Hyperglycemia
The purpose of the study is to see if a low glycemic index diet will reduce blood sugar levels in pregnant women with high blood sugar levels.
- Trial name
- NCT00314717
- Testing
- Control diet, Low GI diet
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University of Toronto
Breast Cancer
BREADS: Breast Adjuvant Diet Study
This is a randomized controlled trial of a 6-month extreme carbohydrate restricted diet (20 grams total carbs/day) via phone counseling with dietitian plus aromatase inhibitor therapy vs.
- Trial name
- NCT04189263
- Testing
- Carbohydrate restricted dietary intervention, standard of care aromatase inhibitors
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Farin Amersi
Dietary Assessment, Growth
Nutrition of Urban-poor Children
The investigators undertook a program to promote the consumption of healthy foods and reduce the prevalence of malnutrition of children below the age of 5 years in an urban-poor community, by 10% year-on-year through nutrition…
- Conditions
- Dietary Assessment, Growth, Nutritional Assessment
- Trial name
- NCT06921135
- Testing
- supplementation, food
- Where
- Malaysia
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Crohn Disease, Absorption; Disorder, Protein
Impact of an Oligomeric Diet in Intestinal Absorption and Inflammatory Markers in Patients With Crohn Disease
This is a randomized, multicenter, translational, triple-blind, clinical trial in patients with Crohn's disease, who will be prescribed an oral nutritional supplement to control symptoms in the acute phase and to recover in the…
- Conditions
- Crohn Disease, Absorption; Disorder, Protein, Absorption; Disorder, Absorption; Disorder, Fat
- Trial name
- NCT04305535
- Testing
- Peptidic+Probiotic
- Where
- Spain
- Volunteers
- 162 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Prediabetes, Obesity / Overweight
Very-Low-Carbohydrate Diet for Prediabetes and Obesity
Prediabetes is a condition where blood sugar is higher than normal but not yet high enough to be called type 2 diabetes. It is common in adults who are overweight or obese, and without treatment it often progresses to diabetes…
- Conditions
- Prediabetes, Obesity / Overweight, VERY LOW CARBOHYDRATE DIET
- Trial name
- VLCBD (NCT07830121)
- Testing
- Standard Dietary Advice, Very-Low-Carbohydrate Diet (VLCBD)
- Where
- Malaysia
- Volunteers
- 33 people
- Sponsor
- Universiti Teknologi Mara
Diabetes Type II
A Pilot Study of the Effects of Diet and Behavioral Interventions on Health in Diabetics
The study is a small pilot, designed to provide data regarding the feasibility and acceptability of conducting such a study on a larger scale.
- Trial name
- SUCCEED (NCT01713764)
- Testing
- Low Carbohydrate Diet, American Diabetes Association Diet, Mindfulness and Positive Affect Skills
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, San Francisco
Gestational Diabetes Mellitus
Trial of Diet in Gestational Diabetes Mellitus: Metabolic Consequences to Mother and Offspring
The rapidly rising risk of gestational diabetes pregnant women demands that an effective diet strategy be developed due to the high risk of fetal overgrowth, which places the newborn at increased risk for childhood obesity and…
- Trial name
- CHOICE (NCT02244814)
- Testing
- Low Carbohydrate/Conventional, Choosing Healthy Options in Carbohydrate Energy
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Colorado, Denver
Asthma in Children
Impact of Modified Specific Carbohydrate Diet on Bronchial Asthma Control in Children
The aim of this study will explore if the specific carbohydrate diet has an effect on asthma control in children and if it will affect the frequency, severity, and duration of asthma and thus provide it as a potential…
- Trial name
- NCT05728385
- Testing
- Modified Specific carbohydrate diet for 3 months
- Volunteers
- 60 people
- Sponsor
- Tanta University
Obesity
Low Carb Diets & Exercise for Cardiovascular Disease (CVD) Reduction
The purposes of this study are: To investigate the effects of a 6 month low carbohydrate diet in obese men on markers of heart health including blood fats, blood clotting factors, inflammatory markers and levels of body fat.
- Trial name
- NCT01176084
- Testing
- low carbohydrate diet, low carbohydrate diet and exercise
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Diabetic Kidney Disease, Cognitive Function
Metabolism of Low Carbohydrate and Ketogenic Diet
This study will assess the preliminary efficacy of a lifestyle intervention including low-carb/ketogenic diet and exercise, enhanced by self-monitoring through health technologies on weight and diabetes outcomes (Glucose, HbA1c)…
- Conditions
- Diabetic Kidney Disease, Cognitive Function, Weight Loss, Diabetic Control
- Trial name
- NCT05071287
- Testing
- mHealth + low-fat diet, mHealth + low-carb/ketogenic diet
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Heat Stress, Diet Induced Thermogenesis
Carbohydrate or Protein Drinks Before Exercise in the Heat
This project examines whether consuming a high-protein or high-carbohydrate beverage before exercise in the heat impacts metabolism and heat balance during exercise, with the following research questions: 1.
- Conditions
- Heat Stress, Diet Induced Thermogenesis, Protein Consumption
- Trial name
- NCT07646990
- Testing
- Protein shake, Carbohydrate shake
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Providence College
Obesity
Energy Balance Weight Regulation Study
The purpose of this study is to test the hypothesis that a low-carbohydrate diet will impact hormones and other factors that regulate appetite and energy balance, and result in lower energy intake and greater weight loss, than a…
- Trial name
- BALANCE (NCT00619008)
- Testing
- Ad libitum low carbohydrate diet, Ad libitum High Complex Carbohydrate Diet, Energy-restricted high complex carbohydrate diet
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Overweight and Obese Women
Impact of Beta-glucan Supplementation During Calorie and Carbohydrate-restricted Diet on Body Weight and Body Fat Loss, Appetite, and Gastrointestinal Appetite Hormones.
This study will investigate whether beta-glucan supplementation, when added to an energy and carbohydrate-restricted diet, facilitates body weight and body fat loss, and leads to less detrimental changes in subjective appetite…
- Trial name
- NCT07299942
- Testing
- Beta-glucan addition to a restricted calorie of meal replacements and carbohydrate diet.
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Child Development
Added Sugar Intake and Brain Structure and Function
The purpose of this study is to learn if there is a relationship between added sugar intake during pregnancy, infancy, and toddlerhood and the brain's structure and function at 5-6 years old.
- Trial name
- GAINS BRAINS (NCT06640829)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Dietary Habits
Impact of Warnings on Sugar-Sweetened Beverages
The purpose of this randomized controlled trial is to determine whether pictorial warnings on sugar-sweetened beverages are more effective than neutral labels at reducing parents' purchases of sugar-sweetened beverages for their…
- Trial name
- NCT04223687
- Testing
- Sugar-Sweetened Beverage Warning Label, Neutral label
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill