Clinical trials: Dietary Fats
Cold Exposure
Energy Dense Fueling for Cold-Weather Operations
High daily energy expenditures without compensatory increases in energy intakes results in severe energy deficits during cold-weather military operations.
- Trial name
- NCT07489690
- Testing
- High Fat, High Carbohydrate
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Atherosclerosis
A Human In Vivo Feeding Study Of The Blood Monocyte Response To Dietary Lipid Intake
The aim of the present study is to identify the effects of different dietary fats on the body's immune system and how different types of cells respond.
- Trial name
- Lipophage14 (NCT02101346)
- Testing
- Mixed High Fat Diet, Saturated fat diet, Monounsaturated fat diet
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Insulin Resistance
Does Class of Dietary Fat Affect Insulin Resistance?
It has been shown that intravenous fatty acids given to normal volunteers in the form of heparin and lipid emulsions will cause insulin resistance in a matter of a few hours.
- Trial name
- NCT01541592
- Testing
- Dietary fat
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Abnormalities, Hyperlipidemia
Study of the Effects of Blackcurrant Extract and Omega-3 Fats on the Health of the Heart and Blood Vessels
Background: Heart disease is the leading cause of death in the United States. Eating fruits and vegetables with chemicals called flavonoids may protect against heart disease and improve blood flow to the heart.
- Conditions
- Abnormalities, Hyperlipidemia, Cardiovascular Disease, Arteriosclerosis
- Trial name
- NCT02019680
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Body Weight Changes
Effect of Dietary Fat When Eaten With Fructose Versus Glucose
This study is designed to test the effects on liver fat of varying fat intake in the presence of fructose or glucose. We hypothesize that higher dietary fat when eaten with fructose as compared to glucose will increase the amount…
- Trial name
- Fructose (NCT01061346)
- Testing
- 40% Fat Diet, 20% Fructose Beverage, 20% Glucose Beverage
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Acute Pancreatitis
The Effect of Dietary Fat Content on the Recurrence of Pancreatitis
This trial aims to test the effects of two different diets on the recurrence of acute pancreatitis, and acute pancreatitis associated mortality.
- Trial name
- EFFORT (NCT04761523)
- Testing
- Dietary intervention: reduced fat diet, Dietary intervention: standard healthy diet
- Where
- Hungary
- Volunteers
- 384 people
- Sponsor
- University of Pecs
Healthy
Oscillations of Dietary Fat/Carbohydrate Intake Over Interval of 3 to 4 Days
The purpose of this study is to understand the mechanisms for oscillations of dietary fat/carbohydrate intake and how fat intake affect insulin resistance and liver fat over interval of 3 to 4 days.
- Trial name
- Dietitian II (NCT01115075)
- Testing
- Dietary fat/intake of carbohydrate, Spontaneous oscillations of dietary fat/intake of carbohydrate in relation to energy intake.
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Healthy, Obesity
Postprandial Inflammatory Response in Healthy Men: Effect of Dietary Fat Source, Obesity and Age
The nature of dietary lipids, age and perivisceral adiposity could alter the postprandial inflammatory response. It is supposed that there is a relationship between the postprandial inflammatory response and the repartition of…
- Trial name
- NCT01066091
- Testing
- Mashed potatoes, Mashed potatoes + Oleic acid, mashed potatoes + Palmitic acid
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Yves Boirie
Headache
Effects of Changes in Dietary Intake and Headache's Attacks
Headache is a frequently disabling disorder, which occurs in about 30% of the adult population, particularly in overweight/obese women.
- Trial name
- NCT01917474
- Testing
- low lipid diet, normal lipid diet
- Where
- 2 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Federico II University
Insulin Resistance
Pilot Study to Test Dietary Fat Delivery
The average American diet consumed by a significant proportion of the adult population, supplies excessive calories and large amounts of saturated fat.
- Trial name
- NCT02101996
- Testing
- high-fat diet
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Hepatic Fat Content
Monitoring of Hepatic Fat Metabolism Using Magnetic Resonance Methods
The first primary research objective of the study is to determine whether high-fat load (150 g of fat) induces increase in hepatic fat content (HFC) three and six hours after meal in insulin-sensitive subjects with normal HFC…
- Trial name
- NCT03680248
- Testing
- Fat, Fasting, Fat+Glucose
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Ectopic Lipids, Insulin Sensitivity
The Effect of Dietary Fat Load and Physical Exercise on the Flexibility and Partitioning of Ectopic Lipids.
This study aims at assessing the effect of standardized dietary fat load and short-term aerobic exercise on systemic lipolysis, flexibility and partitioning of ectopic fat stores (intramyocellular = IMCL, intrahepatocellular =…
- Conditions
- Ectopic Lipids, Insulin Sensitivity, Aerobic Exercise, Fat Load
- Trial name
- NCT01467193
- Testing
- Fat diet, 2h standardized aerobic exercise
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiovascular Disease
Effects of Lipemia and Metformin on Endothelial Function
Eating a diet high in fat contributes to the development of atherosclerosis (hardening of the arteries). Acute fat consumption increases levels of fat in the blood and temporarily reduces the ability of blood vessel to dilate…
- Trial name
- NCT01037660
- Testing
- Metformin
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Boston University
Type 2 Diabetes Mellitus
Optimal Dietary Fat Pattern to Prevent Cardiovascular Disease Among Type 2 Diabetes
Cardiovascular complications are the leading cause of death among type 2 diabetic patients. Postprandial triglyceride-rich lipoproteins (ppTRLs) are atherogenic.
- Trial name
- NCT00467168
- Testing
- Diet
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Dietary Fats, Pharmacokinetics
The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib
An open label, three way crossover study to determine the effect of a high fat breakfast or a low fat breakfast on the pharmacokinetics of a single dose of regorafenib.
- Trial name
- NCT01002378
- Testing
- Regorafenib (Stivarga, BAY73-4506)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Insulin Resistance
The Effect of Liraglutide on Dietary Lipid Induced Insulin Resistance in Humans
In this research study, investigators will test the effects of an approved medication for diabetes,Liraglutide, to reduce insulin resistance that develops from eating a diet high in saturated fats.
- Trial name
- NCT02403284
- Testing
- Liraglutide, Sugar Pill
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Phoenix VA Health Care System
Dietary Modification
Trial of Different Dietary Fat Sources on Blood Lipids and Other CVD Risk Factors
This is a randomised trial in which healthy volunteers, men and women aged 50-75 years from the general community are randomized into one of three arms: participants will be provided with 50 gm extra virgin coconut oil, or 50…
- Trial name
- COCHEESE (NCT03401281)
- Testing
- Coconut oil, Butter, Olive oil
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Reading
Obesity
Obesity, Physical Inactivity or Dietary Fat ?
Obesity is the consequence of a chronic disequilibrium of fat balance. Genetic factors determine predisposition to obesity, but the most often mentioned idea is that environmental factors, such as a high-fat diet and a sedentary…
- Trial name
- NCT00434265
- Testing
- Physical training
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Strasbourg, France
Effect of Diet on Microbiome Composition
Controlled Feeding Experiment
The purpose of this study is to determine the effect of dietary fat, in standard formulation, on the composition of the human microbiome in a prospective study of normal volunteers.
- Trial name
- CaFE (NCT00951756)
- Testing
- High fat diet
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- James Lewis
Hypercholesterolemia
Effect of a Treatment With a Nutraceutical Combination on Sub-optimal LDL Cholesterol Levels
High cholesterol is one of the major controllable risk factor for coronary heart disease. It is well demonstrated that drugs that reduce the intestinal absorption of cholesterol or block the synthesis of cholesterol or the…
- Trial name
- NATCOL (NCT03739242)
- Testing
- Nutraceutical combination
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- A. Menarini Industrie Farmaceutiche Riunite S.r.l.