Clinical trials: Dietary Fibre
Irritable Bowel Syndrome
Effect of Butyrogenic Fibers in IBS Patients
Despite there being no clearcut advantages, one of the most common recommendations in IBS management is to increase the amount of dietary fibres. In some IBS patients fibres have a deleterious effect on pain and bloating.
- Trial name
- NCT00314886
- Testing
- Diet
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Caries; Dentin
Clinical Evaluation of Bulk-fill Restorative Materials
High-viscosity glass ionomer cements have been developed to improve the weak mechanical properties of glass ionomer cements, increase wear resistance and improve their limited indications.
- Trial name
- NCT06109987
- Testing
- World Dental Federation criteria (FDI)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Recep Tayyip Erdogan University
Cardiovascular Risk Factor, Cholesterol; Lipidosis
Meta-analysis of the Portfolio Dietary Pattern and Cardiometabolic Risk
The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Portfolio diet, a dietary pattern that includes nuts, viscous fibre, plant protein, and plant sterols.
- Trial name
- NCT03534414
- Testing
- Portfolio Dietary Pattern, NCEP Based Diet
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Class II Dental Restorations
Clinical Performance of an Innovative Self-cure Bulk-Fill Composite Compared to Dual-Cure and Light-Cure Bulk-Fill Composite in Posterior Restorations.
This clinical trial aimed to compare the 1-year clinical performance of a self-cure bulk fill (Stela Capsules), a dual-cure bulk fill (Fill-Up), and a light-cure bulk fill (Tetric N-ceram bulk fill) in class II dental composite…
- Trial name
- NCT07410468
- Testing
- Group I (n=20): were restored with self-cure bulk-fill., Group II (n=20): were restored with dual-cure bulk-fill., Group III (n=20): were restored with light-cure bulk-fill.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Marwan Abdelnaser
Appetite Suppression, Weight Loss
Effects of a Dietary Fibre Supplementation of a Low Calorie Diet on Appetite and Body Weight
This 18 week, randomized, double blind, placebo controlled trial will examine the effects of thick dietary fibre (PGX) supplementation of a low calorie diet (LCD) on appetite, weight loss, body composition, and compliance in…
- Trial name
- NCT01109199
- Testing
- PolyGlycopleX (PGX), Rice flour
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Early-onset Colorectal Cancer, Late-onset Colorectal Cancer
Distinct Metastatic Phenotypes Between Early-onset and Late-onset Colorectal Cancer
The clinical and pathological features of early-onset colorectal cancer (EOCRC) differ from those of late-onset colorectal cancer (LOCRC).
- Trial name
- NCT06040021
- Testing
- standardized treatment
- Volunteers
- 15,244 people
- Sponsor
- Fudan University
Breast Cancer, Triple Negative Breast Cancer
TNBC Gut Microbiota During Neoadjuvant Treatment
The gut microbiome is made up of the microbes (such as bacteria, viruses, and other organisms too small to see with the naked eye) that live in the digestive tract and has been shown to be important in metabolizing food…
- Conditions
- Breast Cancer, Triple Negative Breast Cancer, Early Stage Triple-Negative Breast Carcinoma
- Trial name
- NCT06610097
- Testing
- Nutritional Counseling
- Where
- United States
- Sponsor
- Scripps Health
Healthy
Dietary Fiber, Microbiota and Cognitive Function in Healthy Adults
Dietary fiber is well-known for its many health benefits, including the support of gastrointestinal, metabolic, and mental health.
- Trial name
- FOCUS (NCT04951674)
- Testing
- High fiber diet, Control diet
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University College Cork
Ulcerative Colitis
Personalized Anti-Inflammatory Fibres in Ulcerative Colitis
The goal of this clinical trial is to determine the clinical effects of two different dietary fibre supplements, acacia gum (AG) and microcrystalline cellulose (MCC), in patients with ulcerative colitis.
- Trial name
- PAIF-UC (NCT06515210)
- Testing
- Acacia Gum, Microcrystalline Cellulose
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- University of Alberta
Healthy Volunteers
Effect of Three Fibres on Glycaemic and Insulinaemic Responses in Healthy Adult Volunteers
The purpose of this study is to determine whether DuPont Experimental Dietary Fibre products 1 and 2 are digested using glycaemic and insulinaemic response as markers.
- Trial name
- NCT02701270
- Testing
- Experimental Dietary Fibre 1, Experimental Dietary Fibre 2, Polydextrose
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Danisco
Weight Loss, Adolescent Obesity
The Effect High Protein-Fiber Diet With Exercise on Acylated Ghrelin and Leptin in Obese Adolescents
Obesity has been reported to impair regulation of appetite and lead uncontrollably hunger and satiety response. Ghrelin is orexigenic hormone from the stomach meanwhile, leptin is anorexigenic from adipose.
- Trial name
- NCT04377906
- Testing
- Modification Lifesyle
- Where
- Indonesia
- Volunteers
- 56 people
- Sponsor
- Universitas Diponegoro
Diabetes Mellitus
The Effect of Dietary Fiber-enriched Cereals on Glycemic Control and Secretion of Gut Hormones
The aim of this study is to assess whether dietary fiber-enriched cereals effect on postprandial glucose levels and plasma glucagon-like peptide 1 (GLP-1) and/or glucose-dependent insulinotropic polypeptide (GIP) concentration in…
- Trial name
- NCT01997281
- Testing
- dietary fiber-enriched cereal, conventional cereal
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Seoul National University Hospital
Gastric Emptying, Intestinal Transit Time
Impact of Different Dietary Fibers in Gastric Emptying Time and Intestinal Transit of Healthy Volunteers
The digestive process begins in the mouth and follows in the stomach and intestine. In the stomach the food is mixed with the gastric juices forming the chyme.
- Trial name
- NCT03982836
- Testing
- Soluble Dietary Fibers
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Type 2 Diabetes (T2DM)
The Effect of OptiFibre Dietary Fiber on Carbohydrate Metabolism and Intestinal Microbiota Metabolism in Patients With Type 2 Diabetes Mellitus
The goal of this clinical trial is to to study the effect of Optifiber PHGG on carbohydrate metabolism in patients with type 2 diabetes mellitus. The main questions it aims to answer are: 1.
- Trial name
- NCT07609992
- Testing
- Nestle Optifibre
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Pirogov Russian National Research Medical University
Class I Dental Caries
CLINICAL COMPARISON OF DIFFERENT GLASS IONOMER-BASED RESTORATIVES AND A BULK-FILL RESIN COMPOSITE IN CLASS I CAVITIES: A 48-MONTH RANDOMIZED SPLIT-MOUTH CONTROLLED TRIAL
The aim of this study is to compare the clinical performances of high-viscosity glass ionomer (GI), glass carbomer (GC), zirconia-reinforced GI (ZIR), and bulk-fill (BF) composite resin restorations.For this purpose, two…
- Trial name
- NCT05559333
- Testing
- class I restoration placement
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Signs and Symptoms, Digestive
Acute Gastrointestinal Tolerability Following a Single Serving of a Novel Dietary Fiber
The study will assess the gastrointestinal tolerability of a single serving of a novel dietary fiber at three different dose levels in generally healthy men and women.
- Trial name
- NCT02530762
- Testing
- Novel Fiber, Positive Fiber control, Negative Control
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cargill
Digestive Health, Metabolic Health
Investigating the Tolerability of Oat Fiber (BG-OS) in Healthy Individuals
The goal of this interventional study is to evaluate the tolerability and potential health benefits of oat fiber oligosaccharide (BG-OS) in healthy adults aged 18-70 years.
- Trial name
- NCT06739941
- Testing
- Oat fiber (BG-OS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- One Bio Inc.
Microbiome
Feasibility of a Lifestyle Intervention for Women With Triple-negative Breast Cancer Under Neoadjuvant Immunotherapy
Triple-negative breast cancer (TNBC) is considered a tumor with a high risk of recurrence and metastasis and requires aggressive systemic therapy combining immunotherapy and chemotherapy.
- Trial name
- BallastImmun (NCT07311083)
- Testing
- switching to a high-fibre diet, official dietary recommendations
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Kliniken Essen-Mitte
Hyperglycemia
Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults
This study tested the effects of resistant starch type 4 on blood sugar and hunger in young adults with Type 2 diabetes.
- Trial name
- NCT00687960
- Testing
- Resistant starch type 4 - raw, Resistant Starch Type 4 - Cooked, Dextrose
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Hypercholesterolemia
Intervention With Lupin Kernel Fibre in Hypercholesterolemic Subjects
The objective of the conducted study was to determine the efficacy of lupin kernel fibre-enriched food (Lupinus angustifolius Boregine) on prevention of risk factors for gastrointestinal or cardiovascular diseases.
- Trial name
- NCT01035086
- Testing
- fabricated food
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Jena