Clinical trials: Dietary Intervention
Rheumatoid Arthritis
A Nutrition Intervention for Arthritis -3 (WCCR-ARTH3)
The purpose of the study is to assess whether, in individuals with rheumatoid arthritis, a low-fat, vegan diet improves pain and other subjective symptoms more effectively than a control supplement or a placebo.
- Trial name
- NCT03417648
- Testing
- Plant-based diet, Supplement
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Physicians Committee for Responsible Medicine
Inflammation, Diet Modification
Watermelon Focused Dietary Inflammatory Index Intervention
A large, persuasive, and ever-increasing body of evidence links chronic inflammation to virtually all of the chronic diseases that cause the majority of disability and death in the U.S., including diabetes, cardiovascular…
- Trial name
- IMAGINE (NCT03158740)
- Testing
- DII-Based Counseling System, general health education control
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Michael D. Wirth
Psoriatic Arthritis
Diet Interventions in Psoriatic Arthritis
The purpose of this study is to learn whether changing diet impacts psoriatic arthritis (PsA).
- Trial name
- DIPSA (NCT04180904)
- Testing
- Diet 1, Diet 2
- Where
- 2 sites in United States, Canada
- Volunteers
- 92 people
- Sponsor
- University of Pennsylvania
Chronic Kidney Disease
Reduced Calorie Diet Intervention in Kidney Transplant Recipients
The purpose of this study is to measure the effect of a reduced calorie diet intervention in new kidney transplant recipients on the outcomes weight gain, oxidative stress, and insulin resistance.
- Trial name
- NCT00994838
- Testing
- reduced calorie diet
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Vanderbilt University
Colorectal Cancer
Vitamin D Intervention and Associated Changes in the Gut Microbiome and Vitamin D Levels in Healthy Adults
Although dietary vitamin D supplementation has been used in the clinical setting for decades, the effect of supplementary vitamin D consumption on the structure of the microbiome has not been studied in humans in fine scale or…
- Trial name
- VDMT (NCT05387876)
- Testing
- Vitamin D intervention
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Baylor University
Heart Failure
The Effect of Action Control Based Intervention on Adherence After Cardiac Rehabilitaiton
This will be a pilot study of the effect of an Action Control-based intervention (ACBI) on adherence to prescribed diet and exercise programs after cardaic rehabilitation. The purposes of this study are to: 1.
- Trial name
- NCT00602485
- Testing
- Action Control Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Summa Health System
Diet Modification
Metabotypes in the Urinary Excretion of Flavan-3-ol Metabolites: "Metanols"
Flavan-3-ols are the main source of flavonoids in Western diets. They are characteristic compounds of tea, cocoa, wine, apple, pears, etc.
- Trial name
- Metanols (NCT04124016)
- Testing
- Inulin, green tea extract, grape seed
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Parma
Diet Modification
Increasing Lean Protein Intake in Preschool-age Children and Assessing Effects on Cognition and Select Health Outcomes
The proposed project addresses the goal of exploring preschooler's ability to recognize changes in feelings of hunger/satiety based on consuming a snack and a meal (lunch/dinner) that are either based on the usual childcare…
- Trial name
- NCT06882252
- Testing
- Low glycemic index diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sibylle Kranz, PhD, RDN
Diabetes Mellitus, Type 1
Can Gluten-free Diet Prevent the Destruction of Beta-cells During Remission?
Type 1 diabetes (T1D) emerge when the auto-immune destruction exceeds the beta cell's regenerative capacity. The patients' beta-cell capacity increases shortly after onset when glucotoxicity decreases after the start of insulin…
- Trial name
- NCT02284815
- Testing
- Glutenfree diet
- Volunteers
- 20 people
- Sponsor
- Herlev Hospital
Leukemia, Lymphoma
Nutrition and Physical Activity Intervention in Preventing Excess Weight Gain in Pediatric Patients With Leukemia or Lymphoma Treated With Prednisone and/or Dexamethasone
This trial studies how well a nutrition and physical activity intervention works in preventing excess weight gain in pediatric patients with leukemia or lymphoma treated with Treated with prednisone and/or dexamethasone.
- Trial name
- NCT05049785
- Testing
- Counseling, Exercise Intervention, Informational Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity & Overweight, Gestational Diabetes Mellitus in Pregnancy
Evaluation of Nutritional Interventions to Limit Gestational Weight Gain in Women With Class III Obesity (BMI >40)
Women with obesity who gain more weight than recommended during pregnancy are more likely to have problems such as cesarean delivery, diabetes in pregnancy, high blood pressure, and larger babies.
- Conditions
- Obesity & Overweight, Gestational Diabetes Mellitus in Pregnancy, Gestational Weight Gain, Morbid Obesity
- Trial name
- OPTIMAL (NCT07828743)
- Testing
- Nutrition education
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Alabama at Birmingham
Psoriasis
Efficacy Study of Dietary Intervention and Weight Loss in Improving Psoriasis
This is a multicenter randomized controlled clinical trial evaluating the impact of a structured non pharmacological intervention consisting in intensive weight reduction (qualitative and quantitative changes in diet associated…
- Trial name
- NCT01714284
- Testing
- Informative, Diet and Exercise
- Where
- 11 sites in Italy
- Volunteers
- 303 people
- Sponsor
- Centro Studi Gised
Type 2 Diabetes
Effects of Peanut and Peanut Butter Consumption on Blood Lipids and Glycemic Control in Adults With Type 2 Diabetes
Peanuts and peanut butter contain high levels of monounsaturated fat (MUFA), arginine, fiber, phytosterols, resveratrol and vitamin E that have the potential to reduce cardiovascular disease (CVD) risk through improved blood…
- Trial name
- NCT00937222
- Testing
- Peanuts and peanut butter
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Loma Linda University
Diabetes Mellitus, Type 2, Obesity
Microbiome and Health Indicators in People With Obesity, Prediabetes and Type 2 Diabetes Undergoing a Lifestyle Intervention
The incidence of type 2 diabetes worldwide is growing rapidly, being one of the fastest growing global health emergencies of the 21st century according to the International Diabetes Federation.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, PreDiabetes
- Trial name
- MicrobiAr (NCT05372445)
- Testing
- Non-intensive intervention, Intensive intervention
- Where
- Argentina
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Healthy Male Subjects
Properties of Dietary Fibre and Energy Intake
Dietary fibers likely have a role in body weight management. They may increase satiety and, as a consequence, reduce energy intake during the next meal.
- Trial name
- ProVe (NCT01257295)
- Testing
- control: no fiber addition, breakfast with low viscous, low gelling pectin, high viscous, low gelling pectin
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Diabetes, Diabetes Mellitus, Type 2
INITIATE Plus (INITiation of Insulin to Reach A1c TargEt) Study
This trial is conducted in the United States of America (USA). The purpose of this study is to compare the effectiveness and safety of a biphasic insulin aspart standard titration regimen when coupled with dietary intervention to…
- Trial name
- INITIATE plus (NCT00101751)
- Testing
- biphasic insulin aspart, dietary regimen
- Where
- United States
- Volunteers
- 4,877 people
- Sponsor
- Novo Nordisk A/S
Cystic Fibrosis, Cystic Fibrosis-related Diabetes
A Pilot Study of a Low Glycemic Load Diet in Adults With Cystic Fibrosis
This pilot study will evaluate the safety and tolerability of a low glycemic load dietary intervention in adult patients with cystic fibrosis (CF) in a rigorous feeding study.
- Conditions
- Cystic Fibrosis, Cystic Fibrosis-related Diabetes, Cystic Fibrosis With Intestinal Manifestations
- Trial name
- NCT04519853
- Testing
- Low Glycemic Load Diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston Children's Hospital
Alzheimer Disease
Nutrition Interventions for Cognitive Enhancement
By doing this study, researchers hope to learn how the Mediterranean and low-fat eating patterns affect memory, brain volume, brain antioxidant status and cardio-metabolic biomarkers, such as blood pressure and blood glucose, in…
- Trial name
- NICE (NCT03841539)
- Testing
- Mediterranean Diet, Study Supplement, Low-fat Diet
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Social Isolation, Meals
Evaluating the RelAte Mealtime Program as an Intervention to Treat Social Isolation and Improve Cooking Behaviour Among Older Adults Living Alone
The purpose of this study is to evaluate the impact of a psychosocial and nutritional intervention, entitled "RelAte", on cooking and mealtime behaviours of older adults who are living alone and at risk of social isolation.
- Trial name
- RelAte (NCT02007551)
- Testing
- Mealtime Intervention
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Bipolar Disorder
Dietary Intervention for Bipolar Disorder
Bipolar disorder (BD) is a chronic, often disabling illness, and many individuals remain symptomatic despite pharmacotherapy. Significant mood variability often persists throughout the lifespan and predicts relapse, leading to…
- Trial name
- NCT02272010
- Testing
- Experimental Diet, Comparator Diet
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Milton S. Hershey Medical Center