Clinical trials: Dietary Interventions
Obesity and Overweight, Pre-diabetic
Targeted Precision Nutrition Strategy To Prevent Chronic Metabolic Diseases
Nutrition is very important to keep blood sugar levels balanced. If blood sugar levels are too high, it can lead to diseases such as cardiovascular disease and type 2 diabetes (T2DM).
- Conditions
- Obesity and Overweight, Pre-diabetic, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- PRECINUT (NCT06923644)
- Testing
- Optimal Metabotype-specific diet, Sub-optimal diet
- Where
- 2 sites in Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chronic Lymphocytic Leukemia (CLL)
Dietary Intervention With High Phenolic EVOO in CLL
Daily intake of extra virgin olive oil (EVOO), which is the major component of the Mediterranean diet and also a source of monounsaturated fat, may be partly responsible for the increased life expectancy of the Mediterranean…
- Trial name
- NCT04215367
- Testing
- High phenolic EVOO intake, No High phenolic EVOO intake
- Where
- Greece
- Volunteers
- 21 people
- Sponsor
- University of Peloponnese
DNA Damage, Inflammation
The Effects of Foods on Cell Damage Study
Studies have shown that certain compounds inside vegetables can reduce the risk of cancer. Carrots in particular have an association with reduced incidence of colorectal, bladder and breast cancer.
- Trial name
- NCT02696811
- Testing
- White carrots, Oat biscuits
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Diet Modification
Pharmacist-led Therapeutic Nutritional Intervention in Type 2 Diabetes
Type 2 diabetes represents a significant burden to both the individual and our healthcare system. Individuals with type 2 diabetes are typically prescribed one or more glucose-lowering medications, many of which have undesirable…
- Trial name
- NCT03181165
- Testing
- Low-carbohydrate Therapeutic Nutrition
- Where
- Canada
- Volunteers
- 188 people
- Sponsor
- University of British Columbia
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
The Effect of the DASH Diet on Clinical and Metabolic Parameters in Children With MASLD
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in childhood is becoming increasingly prevalent, paralleling the rise in obesity rates, and has become the most common chronic liver disease in the pediatric…
- Trial name
- NCT07480811
- Testing
- DASH Diet, Standart Diet, Physical Activity
- Volunteers
- 88 people
- Sponsor
- Antalya Training and Research Hospital
Food Habits
Fostering Healthy and Sustainable Diets Through School Meals
School meals have considerable potential to shape children's diets and reduce the climate impact of meals. This study applies linear programming for developing and implementing a climate friendly, nutritious and affordable school…
- Trial name
- OPTIMAT (NCT04168632)
- Testing
- OPTIMAT
- Where
- Sweden
- Volunteers
- 1,635 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Disorders of Gut-brain Interaction, Lifestyle and Dietary Interventions
Comprehensive Management Strategies for Gastroesophageal Reflux Disease: A Study of Multidimensional Interventions and Health Impacts
Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder, with around 80% of patients experiencing nighttime symptoms.
- Conditions
- Disorders of Gut-brain Interaction, Lifestyle and Dietary Interventions, Gastroesophageal Reflux Disease
- Trial name
- NCT07754721
- Testing
- Dietary intervention guided by a nutritionist, Written dietary education intervention
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Hualien Tzu Chi General Hospital
Cognitive Dysfunction, Cognitive Disorder, Dietary Supplements
INSIDE: Intervention in Nutritional Supplementation to Improve Cognitive Decline in Elderly.
This study investigates the effect of nutritional supplementation on cognitive performance in older adults over a 90-day period using a double-blind randomized controlled design.
- Trial name
- INSIDE (NCT07000500)
- Testing
- Nutritional Supplement
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Maria Paço
Coronary Artery Disease
Multidisciplinary Program Based in High Intensity Interval Training and Dietary Education for Coronary Artery Disease
A multidisciplinary program based on physiotherapy and diet education will be carried out for 3 months in patients with coronary artery disease with percutaneous coronary intervention.
- Trial name
- NCT03796234
- Testing
- Dietary and physiotherapy, Physiotherapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Malnutrition
Trial to Test the Growth-Promoting Effect of Fortified Spreads When Used as Complementary Food for Infants
This study tests the hypothesis that infants receiving fortified spread as a complementary food for one year grow better and do not become malnourished as often as infants who are provided with maize-soy flour for complementary…
- Trial name
- NCT00131209
- Testing
- fortified spread (RUTF), maize and soy flour
- Where
- Malawi
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tampere University
Overweight, Obesity
Toddler Overweight Prevention Study Among Low-Income Families
The hypothesis is that toddlers with parents who are randomized to a parenting intervention and toddlers with parents who are randomized to the maternal intervention focused on maternal diet and physical activity will be more…
- Conditions
- Overweight, Obesity, Depression
- Trial name
- TOPS (NCT02615158)
- Testing
- Maternal Physical Activity and Nutrition, Parenting, Child Safety
- Where
- 2 sites in United States
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Immunosuppression, Hyperlipidemias
Cholesterol and Fatty Acid Synthesis in Islet and Liver Transplant Patients and Effect of Dietary Intervention
The purpose is to investigate possible mechanisms of increased blood lipid levels following transplantation, and also to see if a comprehensive dietary intervention is effective in reducing blood lipid levels in post-transplant…
- Conditions
- Immunosuppression, Hyperlipidemias, Diabetes Mellitus, Type 1
- Trial name
- NCT00947635
- Testing
- Dietary intervention - supplements
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Quantity and Variety of Vegetables Consumed
DELIVER Evaluation in Nigeria
The DEcent LIVelihoods for small-scale producers delivered through Economic \& Resilient food systems in Nigeria (DELIVER) (2024-2027) project is designed to address the low per capita consumption of vegetables and variety of…
- Trial name
- NCT06927674
- Testing
- Consumption of vegetables
- Where
- Nigeria
- Volunteers
- 1,568 people, healthy volunteers welcome
- Sponsor
- RTI International
Obesity
Dietary Intervention for Visceral Adiposity
The purpose of this research study is to determine whether increased intake of dietary fiber during a 12-week, low-calorie weight loss intervention affects abdominal fat change and improves cardiovascular risk factors in…
- Trial name
- DIVA-Pilot (NCT01350518)
- Testing
- Benefiber, TrueLemon
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Dietary Intervention
Eating to Adjust the Timing System
The goal of this clinical trial is to test the effects of dietary composition on the rhythms of food intake, appetite regulation, and rhythms of energy expenditure.
- Trial name
- EATS (NCT05800990)
- Testing
- dietary intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes Mellitus
Continuous Glucose Monitoring (CGM) in Subjects With Type 2 Diabetes Taking Twice-Daily Exenatide or Once-Weekly Exenatide
The purpose of this substudy is to obtain CGM data from individuals taking exenatide. The CGM measurements gathered before starting and during treatment with exenatide IR and/or exenatide LAR will help determine the…
- Trial name
- NCT00803920
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- HealthPartners Institute
Hypertension, Food Insecurity
DASH Diet Intervention for Systemic Hypertension in Adolescents
Parallel randomized clinical trial comparing DASH produce home delivery to routine care for the management of elevated blood pressure and hypertension in adolescents.
- Trial name
- DISH (NCT06616818)
- Testing
- DASH-FV, nutrition counselling only
- Where
- United States
- Sponsor
- Nemours Children's Clinic
Overweight and Obesity
Sulfur Amino Acids, Energy Metabolism and Obesity
The primary objective of the trial is to establish the effects of dietary sulfur amino acid (SAA) restriction on body weight, body composition and energy expenditure in humans.
- Trial name
- STAY (NCT04701346)
- Testing
- Low SAA diet, High SAA diet
- Where
- Norway
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Diet, Healthy
Free Living Food Waste Management and Diet Quality Improvement Using Smart Intervention and Food Image Application
The primary aim of this study is to reduce household food waste and improve individual nutrition. This will be achieved using the FoodImageTM smartphone app 1, a novel method for measuring household food acquisition, food intake…
- Trial name
- FoodImage2 (NCT05061888)
- Testing
- Smart Intervention for Food Waste Management and Replacing current diet with Fruits and Vegetables, Smart Intervention for Stress Management
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes
Diabetes Dietary Study- Low Carbohydrate and Low-Fat Diets in Type 2 Diabetes
The purpose of this study is to determine the effects of a low-carbohydrate diet compared to a low-fat/high-carbohydrate diet on glucose control in patients who have Type 2 Diabetes.
- Trial name
- NCT00795691
- Testing
- low-carbohydrate diet, low-fat diet
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Albert Einstein College of Medicine