Clinical trials: Dietary Modifications
Obesity
Evaluation of Pulse Fibre Supplementation on Obesity and the Metabolic Syndrome
The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibre will improve their metabolic status…
- Trial name
- NCT01719900
- Testing
- Pulse fibre, Control
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Stress, Stress (Psychology)
Effect of Magnesium-, Vitamin C- and Grape Seed Extract-Enriched Date Bars on Perceived Stress and Salivary Cortisol Levels in Young Women
This randomized controlled trial aims to evaluate the effect of a 4-week daily consumption of a functional date bar enriched with magnesium, vitamin C, and grape seed extract on perceived stress and salivary cortisol levels in…
- Trial name
- NCT07585422
- Testing
- Functional Bar
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- K.G. Razumovsky Moscow State University of Technologies and Management
Dietary Modification
Bioavailability of Phenolic Compounds in Bread
The consumption of wholemeal cereals has been associated with the reduction of several chronic diseases. The mechanisms behind these protective effects may be linked, besides dietary fiber and micronutrients, to an increased…
- Trial name
- NCT02353234
- Testing
- Bread
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Parma
Diet, Healthy
The Effects of Dietary Fibres on Metabolic Health and the Gut Microbiome
The study involves intake of dietary supplements, which are commonly found in the UK diet (not pharmacological agents) to test their effects on inflammation in the body and gut microbiome composition.
- Conditions
- Diet, Healthy, Systemic Inflammatory Response
- Trial name
- NCT06580132
- Testing
- Pectin, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Elizabeth Simpson
Dietary Modification, Bread
Testing the Effect of Whole-wheat Sourdough Bread Compared to White Bread on Healthy Individuals
Bread is the most common grain product in the world, with consumption surpassing 3 billion individuals per year. Sourdough whole-grain bread is considered a healthy alternative to white, refined-wheat bread.
- Conditions
- Dietary Modification, Bread, Gastrointestinal Microbiome, Hematologic Tests
- Trial name
- NCT02936362
- Testing
- Consumption of sourdough bread, Consumption of white bread
- Where
- 2 sites in Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Effect of Diet on Breast Milk Composition
A Dietary Intervention to Modify Breast Milk Content in Obese Lactating Women
This study is a nutrition research study designed to look at how healthy meals can influence the content of breast milk. Moms will be provided with meals that follow a Mediterranean diet pattern for 4 weeks.
- Trial name
- NCT03744429
- Testing
- Mediterranean Diet
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Aging
European Project on Nutrition in Elderly People
NU-AGE is a large multidisciplinary consortium (31 partners, from 17 EU countries) involving nutritionists, bio-gerontologists, immunologists and molecular biologists from the most prestigious institutions in Europe, 5 large food…
- Trial name
- NU-AGE (NCT01754012)
- Testing
- Dietary Intervention
- Where
- 5 sites in France, Italy and 3 more
- Volunteers
- 1,190 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Cardiovascular Diseases, Endothelial Dysfunction
Impact of Consuming Plant Sterols on Endothelial Function and Blood Pressure
The purpose of the research is to assess the impact of co-consuming plant sterols-enriched food product as part of a healthy eating pattern diet on endothelial function (brachial artery FMD, vasodilation-related and…
- Conditions
- Cardiovascular Diseases, Endothelial Dysfunction, Metabolic Syndrome, Diet Modification
- Trial name
- NCT03723330
- Testing
- plant sterols, healthy diet
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Healthy
Methionine Intake Microbiota
Pro-inflammatory immune cells play a pivotal role in multiple sclerosis, and the gut microbiota is increasingly recognized as a key factor shaping the immune system.
- Trial name
- NCT07283328
- Testing
- Methionine-restricted diet
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Insulin Resistance, Healthy
Dynamic Connectivity Under Metabolic Constraints
In this study, we investigate the impact of insulin resistance on the acceleration of brain aging, and test whether increased neuron insulin resistance can be counteracted by utilization of alternate metabolic pathways (e.g.…
- Conditions
- Insulin Resistance, Healthy, Diet Modification, Aging
- Trial name
- NCT04840095
- Testing
- Ketones, Glucose
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dietary Modification
Growth of Infants Fed With BabyNes System
The purpose of this study is to assess the growth of infants fed with BabyNes System, compared to the World Health Organization Reference, during the first four months of life.
- Trial name
- NCT01585142
- Testing
- Test formula
- Where
- 4 sites in Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Mood, Diet Modification
The Effect of Glycaemic Index Variation on Blood Glucose and Mood in Healthy Participants Across the Day
This study provided 24 healthy subjects with two diets that varied in their glycaemic index values. One condition was a low GI diet, whilst the other was a high GI diet.
- Conditions
- Mood, Diet Modification, Glucose, Low Blood, Glucose, High Blood
- Trial name
- NCT03344185
- Testing
- Low Glycaemic Diet, High Glycaemic Diet
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Matthew Grout
Overweight and Obesity, Diabetes Mellitus, Type 2
Looking for Personalized Nutrition for Obesity/Type 2 Diabetes Mellitus Prevention
The objectives of this trial are to assess the effects of interactions between genetic factors and diet with various macronutrient intake on the metabolic disorders, obesity and type 2 diabetes risk, prevention, development and…
- Conditions
- Overweight and Obesity, Diabetes Mellitus, Type 2, Metabolic Syndrome, Genetic Predisposition
- Trial name
- NCT03792685
- Testing
- Normo-carbohydrate meal intake, High-carbohydrate meal intake, High-fat meal intake
- Where
- Poland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Dietary Modification
Pasta and Couscous Prepared With Durum Wheat Semolina: Effect on Post-prandial Glucose and Insulin Metabolism
Carbohydrate-based products can influence the post-prandial glycemic response differently based on their ability to be digested, absorbed and to affect rises in plasma glucose.
- Trial name
- NCT03098017
- Testing
- Short pasta (dry), Long pasta (dry), Couscous
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Parma
Diet Quality
Nutricity: An mHealth Nutrition Intervention to Improve Diet Quality Among Latino Children
The overall objective of this application is to pilot test an mHealth nutrition intervention within pediatric clinics serving Latino families and evaluate its potential for implementation.
- Trial name
- NCT06266468
- Testing
- Nutricity
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Healthy Volunteer
Calorie Restriction Intervention Induces Enterotype-associated BMI Loss in Nonobese Individuals
Calorie restriction (CR), which has the potential effect on weight loss and blood amino acids, has been demonstrated to associate with gut microbiota in humans, especially in obese individuals.
- Trial name
- CRDI (NCT04044118)
- Testing
- Low Calorie Diet
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- BGI-Shenzhen
Pregnancy Related, Diet Modification
Motivational Interviewing for Getting Healthy TodaY Study
The present study aims to test and rigorously evaluate the effectiveness of a computer-assisted motivational interviewing (CAMI) intervention that has already been shown to be successful with young women by reducing the risk of…
- Trial name
- MIGHTY (NCT03410225)
- Testing
- CAMI-TPP, CAMI-Fitness
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity, Adolescent
Nutrition Goes to School: a School-based Nutrition Intervention to Promote Healthy Eating Behaviour Among Adolescents
The goal of this cluster randomized controlled pilot trial is to assess the feasibility and effect of a school-based nutrition intervention program called "Nutrition Goes to School" (NGTS) in improving a healthy diet and physical…
- Trial name
- ESTEEM-NGTS (NCT06515288)
- Testing
- Nutrition Goes To School (NGTS) Program Intervention Package, Nutrition Education Capacity Building for Teachers and Management
- Where
- Indonesia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Intestinal Microbiota, Blood Markers
Effect of Diet on Intestinal Microbiota and Obesity Markers in Adults
This study aims to investigate the direct effect of high amounts of dietary fibre and high amounts of red meat in daily diet on intestinal microbiota, anthropometry and obesity markers in healthy adults.
- Trial name
- TORNADO (NCT01449383)
- Testing
- low meat high fibre, high meat low fibre
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Dietary Modification
Pasta and Bread Prepared With Durum Wheat Semolina: Effect on Post-prandial Glucose and Insulin Metabolism
Carbohydrate-based products can influence the post-prandial glycemic response differently based on their ability to be digested, absorbed and to affect rises in plasma glucose.
- Trial name
- NCT03104686
- Testing
- Short pasta (dry), Long pasta (dry), Bread
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Parma