Clinical trials: Dietary Proteins
AMPD3, OMIM*102772, AMP Deaminase Deficiency, AK1, OMIM *103000, Adenylate Kinase Deficiency
A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
Background: Pyrimidine and purine metabolism disorders (DPPMs) affect how the body metabolizes chemicals called pyrimidines and purines.
- Conditions
- AMPD3, OMIM*102772, AMP Deaminase Deficiency, AK1, OMIM *103000, Adenylate Kinase Deficiency, AMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency, TPMT, OMIM *187680, Thoipurines, Poor Metabolism of
- Trial name
- NCT06092346
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Healthy Diet, Cardiovascular Risk Factor
Effects of Proportioning Meat and Plant-based Protein-rich Foods on Cardiovascular Disease Risk Factors (S58)
This project will assess the effects of consuming different proportions of red meat (RM) and plant-based, protein-rich foods (nuts, seeds, and soy products - NSS) incorporated into a U.S.
- Trial name
- NCT04820829
- Testing
- High RM, low NSS, Moderate RM, Moderate NSS, Low RM, High NSS
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Purdue University
Hypercholesterolemia
Soybean Based Diets and CVD Risk Factors
To evaluate the impact of soybean processing as well as the effect of soy relative to animal protein, independent of alterations in the fatty acid profile of the diet on CVD risk factors in hypercholesterolemic subjects.
- Trial name
- NCT00175097
- Testing
- Diet: soybeans and products made thereof, Diet: soybean flour and products made thereof, Diet: soybean milk
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Tufts University
Heart Failure
High-Protein Diet and HMB Supplementation in Patients With Heart Failure
The goal of this clinical trial is to evaluate the effects of a high-protein diet with or without HMB supplementation compared with a normoprotein diet on clinical, nutritional, and functional outcomes in patients with heart…
- Trial name
- NCT07731048
- Testing
- β-Hydroxy-β-Methylbutyrate (HMB), Individualized Dietary Counseling
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Meal Frequency, Dietary Habits
Defining Beef and Meal Frequency as Key Components of a Healthy Eating Pattern for Muscle Health and Wellbeing
Adopting a healthy eating pattern is important for meeting dietary recommendations and weight management. Although less clear, it seems reasonable to assume that the eating patterns we typically follow can also affect our…
- Conditions
- Meal Frequency, Dietary Habits, Muscle Protein Synthesis
- Trial name
- NCT04232254
- Testing
- Animal-based Protein Foods, Skewed Protein Distribution, Plant-based Protein Foods
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Lung Cancer
Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet
This study is conducted to test the hypothesis that patients with lung cancer undergoing treatment with immunotherapy, chemotherapy and tyrosine Kinase Inhibitors receiving a high protein diet and supplemented with fish oil will…
- Trial name
- NCT04965129
- Testing
- Fish oil
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Insulin Resistance, Impaired Glucose Tolerance
Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight and Prediabetes (DISTAL)
The purpose of this study is to investigate the effects of a fibre mixture added to a high-protein diet on metabolic, gut and brain health.
- Conditions
- Insulin Resistance, Impaired Glucose Tolerance, PreDiabetes, Overweight and Obesity
- Trial name
- DISTAL (NCT05354245)
- Testing
- Fibre supplement (potato-pectin), High-protein diet
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Protein Fermentation, Toxicity in the Colon
Effect of Increased Protein Intake on Colonic Metabolism
The purpose of this study is to modulate the protein fermentation and to investigate the effect on colon toxicity.
- Trial name
- NCT01280513
- Testing
- High protein intake, Low Protein intake
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Acceptance, Social
Protein for Life: Towards a Focused Dietary Framework for Healthy Ageing. Consumer Assessment of High Protein Biscuits
As part of the Protein for Life project, design rules have been established which outline the processes which need to be considered when designing higher protein products.
- Trial name
- Protein4Life (NCT03605446)
- Testing
- Biscuit acceptance
- Where
- 3 sites in United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Cancer
Impact of Resistance Training-Protein Supplementation on Lean Muscle Mass in Childhood Cancer Survivors
This study is being conducted because low lean muscle mass is prevalent among childhood cancer survivors. Lean muscle is the non-fatty muscle tissue that makes up part of the body's lean body mass.
- Trial name
- NCT02501460
- Testing
- Educational handouts, Resistance training, Supplementation
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- St. Jude Children's Research Hospital
Healthy
A Study to Evaluate the Influence of Diet on GI Health
The purpose of this study is to understand the potential of protein and psyllium fiber to manipulate gut microbial densities, intestinal permeability, and inflammation in humans.
- Trial name
- NCT04783142
- Testing
- High-fiber, low-protein diet, Low-fiber, high-protein diet
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Exercise, Resistance Training
Overnight Post-Exercise Recovery After Protein Ingestion Prior to Sleep
The purpose of this study is to examine the effects of post-exercise protein ingestion prior to sleep on overnight protein kinetics and muscle recovery.
- Trial name
- NCT00991523
- Testing
- protein
- Where
- 2 sites in Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Severe Obesity
VLCD by Enteral Route for Weight Loss
Body weight excess, from overweight to overt obesity, is associated with adverse health outcomes. In view of the time-trends of the obesity epidemic and the related cost burden, the search for effective strategies for weight…
- Trial name
- NEP (NCT01965990)
- Testing
- NEP
- Where
- Italy
- Volunteers
- 364 people
- Sponsor
- San Giuseppe Moscati Hospital
Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4
Low-Protein Diet With Low-Protein Foods Versus a LPD Without LP Foods in Patients With Chronic Kidney Disease (CKD)
The KDOQI 2020 - Clinical practice guideline for nutrition in chronic kidney disease (CKD) -recommends protein restriction to reduce the risk of end-stage renal disease/death and improve quality of life, a low protein diet…
- Conditions
- Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Chronic Kidney Disease Stage 3A
- Trial name
- NCT05489120
- Testing
- Consumption of FLAVIS
- Where
- 18 sites in France
- Volunteers
- 210 people
- Sponsor
- Dr. Schär AG / SPA
Stage 4 Chronic Kidney Disease
Supplemented Low Protein Diet and Progression of CKD
Investigators intend to analyze diets restricted in protein and supplemented with ketoanalogues of essential amino acids, to slow the progress of renal damage and improve nutritional status in diabetic patients over 60 years with…
- Trial name
- NCT03818568
- Testing
- ketoanalogues of essential amino acids
- Where
- 2 sites in Mexico
- Volunteers
- 149 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Prediabetes / Type 2 Diabetes
Whey Protein Ingestion and Glucose Control in Pre- and Post Diabetic Individuals
To examine the effects of twice daily whey protein consumption on blood glucose and insulin in pre-diabetic and diabetic individuals
- Trial name
- DAIRY (NCT06694155)
- Testing
- Whey Protein Isolate Crossover
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arkansas
ESRD (End-Stage Renal Disease), Dialysis
The Effects of a Dialysis-Specific Formula Rich in Branched-Chain Amino Acids, Omega-3, and Dietary Fiber on Nutritional Status
The aim of this study is to evaluate the effects of a specialized oral nutritional supplement (SF) enriched with BCAAs, omega-3 fatty acids, and dietary fiber on improving the nutritional status of dialysis patients with mild to…
- Trial name
- NCT07060040
- Testing
- BOSCOGEN 18% Protein ONS: Energy 480 kcal, Protein 21.6 g, BCAA 6000 mg, Omega-3 fatty acid 1.8 g, fiber 5 g, Fresubin dialysis ONS (200 ml): Energy 300 kcal, Protein 20 g, BCAA - mg, Omega-3 fatty acid - g, fiber 0.2 g
- Volunteers
- 100 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Obesity
Fruit and Vegetable Juice Concentrate Effects on RBP4 and Antioxidant Capacity in Lean and Overweight 6-10 Year Old Boys
Our study aims to evaluate if the consumption of a Fruit and Vegetable Juice Concentrate (FVJC) vs. placebo can exert changes in the serum levels of Retinol Binding Protein 4 (RBP4), carotenoids, tocopherol, antioxidant capacity…
- Trial name
- FVJC (NCT00842543)
- Testing
- Fruit and Vegetable Juice Concentrate (FVJC)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Nutritional Deficiency
Bioavailability of Zinc and Iron From a Whey-based Protein Supplement Consumed With a Habitual Plant-based Diet
Bioavailability of iron and zinc from habitual plant-based diets consumed by young children in Mexico is low due to the high phytate content.
- Trial name
- NCT02208622
- Testing
- Study 1: Whey Supplement Day 1, Study 1: Whey Supplement Day 2, Study 2: Whey Supplement
- Where
- 2 sites in United States, Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pre-frail, Pre-Frail Older Adults
The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail
This pilot study aims to determine the impact of whey protein supplementation on brain antioxidant levels and to assess the effects of whey protein supplementation on physical function, body composition, and cognition in…
- Conditions
- Pre-frail, Pre-Frail Older Adults, Cognition, Physical Function
- Trial name
- NCT07167277
- Testing
- Whey Protein
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center