Clinical trials: Dietary Supplementation
Safety and Tolerability in Healthy Volunteers
Evaluation of the Safety and Tolerability of Three Doses of Diamine Oxidase (DAO) in Healthy Volunteers
The main aim of this study is to evaluate the safety and tolerability of the product administered, of 3 different doses. Safety will be evaluated by recording and assessing adverse events, vital signs, laboratory tests and ECG.
- Trial name
- DAO-MAX2024 (NCT06715163)
- Testing
- Dose 1 (42mg) of DAO, Dose 2 (84mg) of DAO, Dose 3 (210mg) of DAO
- Where
- Spain
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- AB Biotek
Gut Microbiota Modulation
STUDY OF THE EFFECTS OF L. CASEI DG® (ENTEROLACTIS BABY) IN HEALTHY PRETERM AND FULL-TERM INFANTS.
The goal of this clinical trial was to learn whether giving Enterolactis Baby®, a probiotic food supplement containing Lactobacillus casei DG® (under the new taxonomical denomination: Lacticaseibacillus paracasei DG, CNCM…
- Trial name
- NCT07882537
- Testing
- Enterolactis Baby® drops
- Where
- Italy
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Alfasigma S.p.A.
Female, Healthy Aging
The Impact of Probiotics on Well-being in Women
An exploratory study to determine whether daily supplementation with a probiotic product impacts the overall well-being of women aged between 45 - 65
- Trial name
- ProWOME (NCT06507111)
- Testing
- Lab4P
- Where
- Bulgaria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cultech Ltd
Progesterone Supplementation in Women Undergoing ART
Clinical Safety Study of the Progesterone Vaginal Ring in Women Undergoing Assisted Reproductive Technology Procedures
The purpose of the study is to assess the safety of Progesterone Vaginal Ring (PVR) in women undergoing fresh embryo transfer (ART).
- Trial name
- SARA (NCT03565211)
- Testing
- Progesterone vaginal ring
- Where
- 15 sites in United States
- Volunteers
- 352 people
- Sponsor
- Ferring Pharmaceuticals
Improvement of Functionality
Effects of Daily Nutritional Supplementation in Combination With a Eurhythmics Training (NUDAL)
Malnutrition and lack of regular exercise are often found in older adults and have been identified as important risk factors for independence loss and nursing home admission in older community-dwelling adults.
- Trial name
- NUDAL (NCT01539200)
- Testing
- ONS+JDR, JDR
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Société des Produits Nestlé (SPN)
Muscle Soreness, Muscle Damage
The Chronic Effects of Carnitine on Recovery
This study investigated the effects of CarnipureTM, a high-quality L-carnitine ingredient, on long term (5 weeks) recovery, muscle damage, and SOD status in a population of males and females while training two days per week.
- Conditions
- Muscle Soreness, Muscle Damage, Resistance Training, Oxidative Stress
- Trial name
- NCT04420377
- Testing
- Carnipure, Resistance Training
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Herb-Herb Interaction, Pharmacokinetics
Pharmacokinetics of Kava and Kratom Alone and in Combination
This study is being conducted to evaluate how different formulations of the Feel Free® Tonic containing Kava, Kratom, or a combination of both are processed in the body in healthy adults.
- Trial name
- NCT07583407
- Testing
- Kava and Kratom Herbal Supplement, Kava Herbal Supplement, Kratom Herbal Supplement
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Botanic Tonics, LLC
Vasodilation, Exercise
Acute Effect of Polyphenols Supplementation on Endothelial Function and Exercise Related Markers, in Physically Active Healthy Volunteers.
To evaluate the effect of acute polyphenols supplementation on vasodilation and related markers along with exercise related markers (notably performance, respiratory exchanges, perceived exertion), before, during and after a…
- Conditions
- Vasodilation, Exercise, Healthy Adults
- Trial name
- PolypOxy (NCT07518758)
- Testing
- Oral administration
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nexira
Iron Deficiencies
Impact of Two Iron Formulations on Iron Biomarkers and Quality of Life
This double-blind parallel pilot study will evaluate the safety and efficacy of two Qualia Iron formulations versus placebo in approximately 40 healthy adults (aged 18+) over a 56-day period.
- Trial name
- NCT07156526
- Testing
- Qualia Iron Version A, Qualia Iron Version B
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Qualia Life Sciences
Iron-deficiency
Safety and Effectiveness of Iron Hydroxide Adipate Tartrate (IHAT) in Iron Deficient Premenopausal Women
This is a double blind, randomised, placebo-controlled trial to evaluate orally-dosed Iron Hydroxide Adipate Tartrate (IHAT) at 2 different dose levels compared to placebo for increasing serum ferritin levels in iron deficient…
- Trial name
- NCT06285799
- Testing
- Low Dose IHAT, High Dose IHAT, Carob Flour
- Where
- Australia
- Volunteers
- 180 people
- Sponsor
- Nemysis Ltd
Colorectal Neoplasms
Usefulness of Balanced High Protein Supplementation on Recovery and Clinical Outcomes After Chemotherapy
The goal of this clinical trial is to find usefulness of balanced high protein supplementation on muscle function recovery and clinical outcomes after chemotherapy.
- Trial name
- PROFIT (NCT05938504)
- Testing
- ONS_320275, ONS_211567
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Daesang Wellife
Endothelial Function, Oxidative Stress
Black Forest Cocoa Flavanol Supplementation and Health Trial
This randomized, double-blind, controlled clinical trial will evaluate the effects of daily cocoa flavanol supplementation on vascular and inflammatory biomarkers in healthy adult men aged 30 to 75 years.
- Conditions
- Endothelial Function, Oxidative Stress, Inflamation, Vascular Health
- Trial name
- NCT07747714
- Testing
- Cocoa Flavanol Supplement, Low-Flavanol Control Powder
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Black Forest LLC
Iron Deficiency (Without Anemia)
Low-dose Iron Supplementation in Non-anaemic Iron-deficient Women
The goal of this study is to investigate the efficacy of a low dose iron supplement (6mg) compared to a placebo tablet.
- Trial name
- PCLDIT (NCT05869422)
- Testing
- Iron
- Where
- Switzerland
- Volunteers
- 59 people
- Sponsor
- Dr. Krayenbühl GmbH
Blood Sugar, Endothelial Function
Comparing Blood Sugar Levels and Endothelial Function of PEAK ATP® With GlycoCarn®, PEAK ATP® and GlycoCarn® Supplements
To purpose of this study is to assess the effectiveness, safety and tolerability of PEAK ATP® with GlycoCarn®, PEAK ATP® and GlycoCarn® on levels of blood sugar and endothelial function improvement which may lead to improved…
- Trial name
- NCT01855373
- Testing
- PEAK ATP® with GlycoCarn®, PEAK ATP®, GlycoCarn®
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Gut Health, Gastrointestinal Symptoms
IgG Binding Protein LT in Support of a Healthy Gut on the Go
PS52 is a randomized, double-blind, placebo-controlled, fully decentralized study sponsored by Bactolife A/S and conducted by People Science, Inc.
- Conditions
- Gut Health, Gastrointestinal Symptoms, Safety in Healthy Adults
- Trial name
- NCT07873957
- Testing
- IgG Binding Protein LT
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Bactolife A/S
Healthy
Effects of cogniVida™ on Learning and Memory and in Comparison to Placebo After Long-term Supplementation
The purpose of the study is to examine the efficacy of cogniVida™ on learning and memory performance (executive function, associative, spatial and verbal memory) as well as on mood and attention parameters after four, eight and…
- Trial name
- MemIprov (NCT01647919)
- Testing
- cogniVida™ 100 mg/day
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Dyspepsia
The Effect of a Ginger Supplement on Digestive Complaints in Healthy Adults Versus a Placebo
The aim of this clinical study is to investigate the effect of a ginger formulation as a dietary supplement on gastrointestinal complaints in healthy adults.
- Trial name
- GIGI (NCT06446921)
- Testing
- Ginger formula
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Insulin Sensitivity, Healthy Adult
Diaplex and Glycemic Control
The goal of this 16-week double-blind, placebo-controlled pilot study is to determine whether daily Diaplex supplementation improves insulin sensitivity and glycemic control in adults with elevated blood glucose levels, while…
- Trial name
- NCT07711587
- Testing
- Diaplex
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Menopause, Dietary Supplements
Effects of a New Botanical Extracts Combination on Quality of Life in Menopausal Spanish Women
This study was designed to evaluate the beneficial effects and safety of a standardised botanical extract combination containing soy isoflavone extract, grains of paradise seed dry extract and pomegranate skin dry extract on…
- Conditions
- Menopause, Dietary Supplements, Quality of Life
- Trial name
- NCT04381026
- Testing
- Botanical dry extracts combination
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- Nektium Pharma SL
Aging
Effects of NAD3 Supplementation on Biomarkers of Aging
This is a randomized, parallel-group, placebo-controlled, clinical trial in middle-aged and older male and female subjects from Ohio. Subjects will take an over-the-counter dietary supplement or a placebo for 12 weeks.
- Trial name
- NCT04276948
- Testing
- NAD3
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC