Clinical trials: Dietary Supplementation
Overweight, Obesity
Dietary Supplementation on Fat Oxidation
The purpose of this pilot study is to evaluate the effects of 4 weeks of daily consumption of encapsulated N-trans-caffeoyl tyramine (NCT) and N-trans-feruloyl tyramine (NFT) at a dose of 120 mg/d on measures of fat oxidation in…
- Trial name
- NCT06548048
- Testing
- Dietary supplement containing plant derived phenolics, Microcrystaline cellulose
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Brightseed
Sleep, Sleep Quality
Impact of Nutritional Supplementation on Sleep Quality
This is a randomized, double-blind, placebo-controlled, 5-arm parallel-group study to evaluate the effects of 4 nutritional supplements on sleep over a 12 week period in healthy U.S. adults.
- Trial name
- NCT06935123
- Testing
- Sleep Supplements
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Pharmavite LLC
Gastrointestinal Symptoms
Safety Evaluation of a Diet and Nutritional Supplementation Program- Purify 2.0
The study evaluated the safety, tolerability and acceptability of a lifestyle modification program with nutritional supplementation designed to restore balance to healthy bowel function in generally healthy subjects
- Trial name
- NCT03685552
- Testing
- Prog: Purify-2
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nature's Sunshine Products, Inc.
Healthy Volunteers, Dietary Supplementation
The Impact of 12 Week Retention of Nutrients on Skin and the Perception of Physical Health Status
This is a randomized, double-blind, placebo-controlled clinical trial exploring the effects of a 12-week dietary supplement regimen on skin condition and perceived overall health status.
- Conditions
- Healthy Volunteers, Dietary Supplementation, Skin Health, Health Status
- Trial name
- NCT07383974
- Testing
- Vitamin C & Green Tea Capsules + Multivitamin & Mineral Capsules Combination
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Healthy Aging, Muscle Function
The Effect of Urolithin A (Mitopure®) Supplementation on Muscle Strength in Healthy Middle-Aged Adults
This is a randomised, double-blind, placebo-controlled, parallel study to assess the effects of Urolithin A (Mitopure®) supplementation on muscle strength and performance in healthy middle-aged adults.
- Trial name
- ATLAS 2 (NCT07231783)
- Testing
- Mitopure® 500mg, Mitopure® 1000mg
- Where
- Ireland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Functional Constipation, Healthy
Effect of scFOS on Increase in Stool Frequency in Constipated People
The study aims to evaluate the effects of short-chain fructo-oligosaccharides on the frequency and consistency of stools in subjects with functional constipation.
- Trial name
- CONSYST (NCT03707002)
- Testing
- scFOS, Maltodextrin
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Syral
Effect of Probiotics on Infections in Infants.
Effect of 12-week Probiotic Supplementation on Bacterial and Viral Infections in Infants Aged 6 to 12 Months.
The purpose of this clinical trial is to evaluate the safety and effectiveness of 12-week probiotic supplementation on the incidence and duration of infectious episodes in infants aged 6 to 12 months.
- Trial name
- NCT01724203
- Testing
- Lactobacillus rhamnosus, Bifidobacterium animalis subsp. lactis
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre
Overweight
Bioavailability, Pharmacokinetic and Mechanistic Study of Sinetrol® Xpur, a Polyphenol-rich Ingredient
The purpose of the study is to investigate the metabolization and the bioavailability of bioactive compounds from Sinetrol® Xpur, a polyphenol-rich ingredient, during a 16-week long chronical supplementation.
- Trial name
- NCT03823196
- Testing
- Verum900, Verum1800
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fytexia
COVID-19
Metabolic Cofactor Supplementation and Hydroxychloroquine Combination in Covid-19 Patients
This open label, randomized, controlled, investigator-initiated, multi-centre trial aims to establish metabolic improvements in COVID-19 subjects by dietary supplementation with cofactors N-acetylcysteine, L-carnitine tartrate…
- Trial name
- NCT04573153
- Testing
- Hydroxychloroquine + Metabolic cofactor supplementation, Hydroxychloroquine + Sorbitol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- ScandiBio Therapeutics AB
Exercise Performance Recovery
The Effect of XSurge Supplementation on Biomarkers and Performance From High Intensity Resistance Exercise
Part one of this study will consist of baseline (BL) testing, 28 days of daily supplementation with XSurge, and an exercise protocol.
- Trial name
- NCT02442245
- Testing
- XSurge, Control: No supplementation
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Intestinal Permeability
Dietary Supplementation on Gastrointestinal Barrier Function
The purpose of the current study is to examine the effects of a dietary supplement containing plant derived phenolics at two different dose levels on parameters of gastrointestinal (GI) health in otherwise generally healthy…
- Trial name
- NCT06262880
- Testing
- plant derived phenolics, Microcrystaline cellulose (MCC)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Brightseed
Stress, Attention Disturbances
Impact of Probiotic Supplementation on Cognition and Related Health Outcomes Among Video Gamers
The primary objective of the current study is to investigate the effect of two probiotic formulations on task-switching following acute stress in healthy, adult action video gamers.
- Trial name
- NCT05545813
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Age Related Macular Degeneration
Macula Evolution in Patients With AMD Taking Oral Food Supplementation
LT7082-001 is an open-label, single-arm pilot study. Patients with intermediate age-related macular degeneration (AMD) wil take T7082 during 12 months , an association of 4 food supplementations .
- Trial name
- NCT04778436
- Testing
- T7082
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Laboratoires Thea
Muscle Damage, Muscle
The Effect of Vicia Faba Hydrolysate Supplementation on Muscle Strength Recovery
To investigate the effect of Vicia faba protein concentrate, a protein derived from Fava bean extract, on delayed onset muscle soreness (DOMS).
- Trial name
- NCT06837298
- Testing
- PeptiStrong® supplement capsules following muscle damaging exercise on Day 14
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Drug Safety
Clinical Safety of a Novel Milk Protein Peptide
Background: A novel milk peptide has been shown in laboratory setting to have natural anti-cancer properties and extend lifespan and improve metabolism in animal models.
- Trial name
- NCT01412658
- Testing
- Hydrolyzed milk protein mixture
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Ambryx Biotechnology
Cystic Fibrosis, Failure to Thrive
Clinical Study With an Enteral Formula With Symbiotic and DHA for Malnourished Children
The purpose of this study is to determine whether a nutritional supplement is effective in the treatment of malnutrition in pediatric patients with failure to thrive or cystic fibrosis.
- Conditions
- Cystic Fibrosis, Failure to Thrive, Malnutrition
- Trial name
- VITJUNIOR (NCT02128984)
- Testing
- Symbiotic Formula with DHA and antioxidants, Standard Formula
- Where
- 8 sites in Peru, Spain
- Volunteers
- 109 people
- Sponsor
- Laboratorios Ordesa
Arthralgia
The Effect of AyuFlex® Supplementation on Joint Health
The purpose of this 12-week, prospective study is to determine the effects of oral supplementation with AyuFlex® (an over-the-counter dietary supplement) on joint mobility, joint comfort and functional capacity in healthy…
- Trial name
- NCT02589249
- Testing
- AyuFlex
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Antibiotic Side Effect
The Impact of Probiotic Supplementation on Antibiotic Induced Changes in Gastrointestinal Function And/or Faecal Microbiota Composition
To investigate whether probiotic supplementation during the consumption of oral antibiotics can impact gastrointestinal responses and/or the regrowth of the gut microbiota.
- Trial name
- FANTIB (NCT05355571)
- Testing
- LAB4 + Saccharomyces boulardii
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Cultech Ltd
Osteoarthritis, Knee
Evaluation of Mangoselect® in Improvement of Exercise/Activity-induced Knee Joint Discomfort in Subjects Suffering From Osteoarthritis Grade I or II
The aim of the present investigation is to evaluate the efficacy of Mangoselect®, a mangosteen extract, and of a formulation containing Mangoselect®, in subjects suffering from activity/exercise-induced knee joint…
- Trial name
- NCT04765189
- Testing
- Verum A, Verum B, Verum C
- Where
- Spain
- Volunteers
- 95 people
- Sponsor
- Fytexia
Malnutrition
Quality Improvement Program (QIP) to Reduce 30-Day Readmission in Malnourished Hospitalized Patients
Newly admitted patients will be screened for risk of malnutrition. Patients will receive either the feeding protocol or current oral nutrition supplement (ONS) practice, pending location.
- Trial name
- NCT02262429
- Testing
- ONS QIP, ONS Standard Feeding
- Where
- 4 sites in United States
- Volunteers
- 2,386 people
- Sponsor
- Abbott Nutrition