Clinical trials: Dietary Supplementation
Depression, Anxiety Disorder
Effect of Lactobacillus Plantarum 299v Supplementation on Major Depression Treatment
The aim of the study is to determine the influence of supplementation of probiotic Lactobacillus Plantarum 299V vs. placebo of probiotic during antidepressant monotherapy with SSRI (Selective Serotonin Reuptake Inhibitor) in…
- Trial name
- NCT02469545
- Testing
- Lactobacillus Plantarum 299v, Crystalline cellulose powder, Escitalopram
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Vitamin A Deficiency
Vitamin A, Stool Microbiota and Vaccine Response in Bangladeshi Infants
Vitamin A deficiency (VAD) increases the risk of death from infections in infants and young children. The World Health Organization (WHO) recommends high-dose vitamin A supplementation (VAS) from 6-59 months of age to reduce the…
- Trial name
- NCT02027610
- Where
- 3 sites in United States, Bangladesh
- Volunteers
- 258 people
- Sponsor
- USDA, Western Human Nutrition Research Center
Osteoporosis, Aging
Vitamin D Supplementation in Older Women
The purpose of this study is to examine the effects of several doses of vitamin D on hormones related to bone, calcium absorption, bone density and muscle strength.
- Trial name
- VIDOS (NCT00472823)
- Testing
- Vitamin D3, Calcium Citrate (Citracal)
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- Creighton University
Pediatric Obesity
Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity
This is a pilot study of children between the ages of 8 to 11 years of age who are obese and participating in an intense family based intervention with a family-focused multi-component lifestyle intervention.
- Trial name
- NCT02060279
- Testing
- Lifestyle intervention and carotenoid supplements
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Breast Carcinoma, Cancer
Omega-3 Fatty Acid in Reducing Cancer-Related Fatigue in Breast Cancer Survivors
This randomized pilot clinical trial studies omega-3 fatty acid in reducing cancer-related fatigue in breast cancer survivors. Supplementation with omega-3 fatty acid may help reduce cancer-related fatigue in breast cancer…
- Conditions
- Breast Carcinoma, Cancer, Fatigue
- Trial name
- NCT02352779
- Testing
- Omega-3 Fatty Acid, Questionnaire Administration, Laboratory Biomarker Analysis
- Where
- 6 sites in United States
- Volunteers
- 108 people
- Sponsor
- Gary Morrow
Healthy Persons
Creatine Supplementation on Kidney Function in Resistance-trained Individuals
There is a claim that creatine supplementation might affect kidney function, especially in those consuming a high-protein diet. The aim of this study was to investigate the effects of creatine supplementation on kidney function…
- Trial name
- NCT01817673
- Testing
- creatine
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hypertension
Watermelon Supplementation and Arterial Stiffness
Increased abdominal obesity (waist circumference) and systolic blood pressure (BP) are main risk factors for the metabolic syndrome. Approximately 60% of adults in the United States are prehypertensive or hypertensive.
- Trial name
- NCT01185041
- Testing
- Watermelon Extract
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida State University
Schizophrenia
Influence of Vitamin D Supplementation on Serum BDNF Level and Cognitive Function in Schizophrenia
The objective of the study is to evaluate the influence of vitamin D supplementation on Serum Brain Derived Neurotrophic Factor level and cognitive function in schizophrenia treated with atypical antipsychotic.
- Trial name
- NCT03284294
- Testing
- Cholecalciferol
- Volunteers
- 40 people
- Sponsor
- Universitas Padjadjaran
Chronic Obstructive Pulmonary Disease
Anti-inflammatory Effects of Caffeine in Chronic Obstructive Pulmonary Disease (COPD) Subjects
Nowadays it has become evident that a chronic systemic inflammation is present in patients suffering from chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00826566
- Testing
- Caffeine
- Where
- Netherlands
- Sponsor
- Maastricht University Medical Center
HIV, AIDS
Zinc Supplementation Effect on Immune Recovery in HIV Patients
INTRODUCTION: An adequate zinc supplementation is essential for a good immunological function. However, zinc deficiency is seen in more than 50% of adults infected with HIV.
- Conditions
- HIV, AIDS, Immunological Deficiency, Inadequate Immune Recovery
- Trial name
- NCT02162797
- Testing
- Zinc supplementation
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
Acquired Antithrombin III Deficiency, Coronary Artery Bypass
Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass
The purpose of this trial is to study the effects of preoperative antithrombin supplementation in patients undergoing cardiac surgery with cardiopulmonary bypass in order to maintain antithrombin levels in a range greater than…
- Trial name
- NCT00823082
- Testing
- Antithrombin III
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Instituto Grifols, S.A.
Delirium
Melatonin Supplementation for Delirium Prevention in Acutely Hospitalized Elderly
122 people over 70 who were admitted to hospital were enrolled to the study. Half got .5 mg a night of melatonin, half got a placebo.
- Trial name
- NCT00873379
- Testing
- melatonin
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption
A Study to Investigate the Effect of Vitamin D3 Supplementation on Iron Status in Iron Deficient Women
Iron is one of the most vital elements in humans as it plays a role in physiological functions such as transferring and storing oxygen, transporting electrons and catalysing numerous reactions, from oxidative metabolism to…
- Conditions
- Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption, Vitamin D Deficiency
- Trial name
- NCT02714361
- Testing
- Vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chester
Diabetes, Prediabetic State
The Effect of Vitamin K Supplementation on Glucose Metabolism
The purpose of this study is to test whether vitamin K supplementation has an effect on glucose metabolism in terms of acute beta cell response.
- Trial name
- NCT00960973
- Testing
- Menatetrenone
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hypertension, Pulmonary, Anemia, Iron Deficiency
ORal IrON Supplementation With Ferric Maltol in Patients With Pulmonary Hypertension (ORION-PH-1)
This is an explorative, open-label, uncontrolled, single center study to explore the preliminary safety, tolerability and efficacy of oral ferric maltol in treating iron deficiency in patients with pulmonary hypertension and iron…
- Trial name
- ORION-PH-1 (NCT03371173)
- Testing
- Ferric maltol 30 mg (Feraccru®)
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Hannover Medical School
Polycystic Ovary Syndrome, Insulin Resistance
Effect of Cinnamon Extract on Insulin Resistance in Polycystic Ovary Syndrome
The purpose of this study is to determine whether Cinnamon from the Cassae Plant is effective in the body as insulin could lower blood sugar levels.
- Trial name
- Eccentric (NCT00970541)
- Testing
- Cinnamon Supplementation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Pennington Biomedical Research Center
Gastrointestinal Health, Immune Health
Effect of Bacillus Subtilis BS50 Supplementation on Gastrointestinal Symptoms in Healthy Adults
The primary objective of this study is to investigate the effect of a novel Bacillus subtilis spore preparation on abdominal bloating, flatulence, and burping in healthy adults.
- Conditions
- Gastrointestinal Health, Immune Health, Cardiovascular Health, Digestive Health
- Trial name
- NCT05004454
- Testing
- Bacillus subtilis BS50 spore preparation, Maltodextrin
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- BIO-CAT Microbials, LLC
COVID-19, Vitamin D Deficiency
Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection
The purpose of this study is to evaluate how useful vitamin D supplementation is in reducing the severity of COVID-19 symptoms and the body's inflammatory and infection-fighting response to COVID-19.
- Conditions
- COVID-19, Vitamin D Deficiency, Respiratory Viral Infection
- Trial name
- VitD-COVID19 (NCT04482673)
- Testing
- Daily Vitamin D3, Bolus vitamin D3
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pulmonary Tuberculosis, Pregnancy
Vitamin D3 and Monocyte Responses in Pregnant Women With Pulmonary Tuberculosis
This randomized controlled trial evaluated the effects of adjunctive vitamin D3 supplementation on circulating monocyte subsets and the expression of vitamin D receptor (VDR) and interleukin-6 (IL-6) in pregnant women with…
- Trial name
- NCT07907094
- Testing
- Vitamin D3 (Cholecalciferol), Standard First-Line Anti-Tuberculosis Treatment
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Overweight, Hypertriglyceridemic Waist
Characterization of the Metabolic Fate of an Oral Arginine Form
The purpose of this study is to compare the metabolic fate of two oral forms of L-Arginine in healthy subjects featuring metabolic syndrome related risk factors
- Trial name
- NCT02352740
- Testing
- A form Arginine, B form Arginine
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
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