Clinical trials: Dietary Supplementation
Vitamin D Deficiency
Personalized Vitamin D Supplementation in European and African Americans
The proposed study is a randomized, double-blind, controlled, multi-center clinical trial of six months of daily oral vitamin D3 (cholecalciferol).
- Trial name
- NCT02362269
- Testing
- Vitamin D
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Obesity, Insulin Resistance
Vitamin D Supplementation to Obese Chinese Males
Hypothesis: Oral Supplementation of Vitamin D can Reduce Hypersecretion of Parathyroid Hormone and Insulin Resistance in Obese Chinese Males.
- Trial name
- NCT01781169
- Testing
- Oral supplementation of vitamin D
- Where
- China
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Multiple Sclerosis, Relapsing-remitting
Pharmacokinetics of Vitamin D in Multiple Sclerosis and in Health
This is a pilot study of oral vitamin D supplementation to determine if patients with Multiple Sclerosis (MS) and healthy individuals attain a similar increase in serum 25-hydroxyvitamin D levels.
- Trial name
- NCT01667796
- Testing
- Vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Prostate Cancer
Genistein Supplementation to Mitigate Cardiometabolic Dysfunction in Patients Undergoing Androgen Deprivation Therapy for Prostate Cancer
Genistein is a natural supplement that comes from soy. The purpose of this study is to see if genistein has any effect on preventing or reducing heart disease and diabetes risk in men receiving Androgen Deprivation Therapy for…
- Trial name
- GeniPro (NCT02766478)
- Testing
- Genistein
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Hypoxia
The Effect of Chronic Nitrate Supplementation on Acute Mountain Sickness and Exercise Performance in Hypoxia
The study will aim to describe and evaluate the effect of chronic beetroot juice supplementation on acute mountain sickness symptoms and exercise in a hypoxic environment.
- Trial name
- NCT03101904
- Testing
- Beetroot Juice
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Bangor University
Prostate Cancer
Effects of Sulforaphane on Normal Prostate Tissue
The investigators proposed to identify the biological effects of a high-sulforaphane broccoli sprout extract in normal prostate tissue.
- Trial name
- PHASE (NCT00946309)
- Testing
- High Sulforaphane Extract (Broccoli Sprout Extract)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Fred Hutchinson Cancer Center
Diarrhea, Gastroenteritis
Oral Zinc for the Treatment of Acute Diarrhea in US Children
Diarrheal diseases are the third leading cause of mortality in the world, with nearly 2 million deaths annually among children under age 5 years.
- Trial name
- NCT01198587
- Testing
- Zinc Sulfate
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Boston Children's Hospital
Critical Illness
Safety and Dose Escalation Study of Zinc Supplementation in Critically Ill Children
The purpose of the study is 1) to determine whether administration of intravenous zinc to critically ill children is safe, and 2) to determine an appropriate dose of zinc supplementation.
- Trial name
- NCT01062009
- Testing
- Zinc sulfate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Mild, Allergic Asthma
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS
To test the hypothesis that gamma tocopherol (vitamin E) supplement inhibits endotoxin induced airways inflammation in allergic asthmatics
- Trial name
- Vitalps (NCT02104505)
- Testing
- Gamma Tocopherol 700 mg capsules,
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Kidney Disease
Supplementation With Cholecalciferol in Dialysis Patients
Hypovitaminosis D is highly prevalent among patients with chronic kidney disease, especially in those undergoing dialysis. The loss of protein to the dialysis solution seems to contribute significantly to the reduced serum levels…
- Trial name
- NCT01974245
- Testing
- Cholecalciferol
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Federal University of São Paulo
Chronic Kidney Disease Requiring Chronic Dialysis
Immuno-nutrition Supplementation in Haemodialysis
The purpose of this pilot study is to test if an "immuno-nutrition" supplement can decrease inflammation in people on haemodialysis.
- Trial name
- NCT05700851
- Testing
- Immuno-nutrition supplement
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Nottingham
Premature Birth
Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)
Available data suggest that low dose aspirin may be a safe, widely available and inexpensive intervention that may significantly reduce the risk of preterm birth.
- Trial name
- ASPIRIN (NCT02409680)
- Testing
- Low dose aspirin
- Where
- 14 sites in United States, Democratic Republic of the Congo and 5 more
- Volunteers
- 11,976 people
- Sponsor
- NICHD Global Network for Women's and Children's Health
COVID-19
Study of Intravenous Ampion in Adult COVID-19 Patients Requiring Supplemental Oxygen
This is a Phase 2 randomized study to evaluate the safety and efficacy of IV Ampion in improving the clinical course and outcomes of adult COVID-19 patients requiring supplemental oxygen.
- Trial name
- NCT04839965
- Testing
- Ampion, Saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Oxidative Stress, Inflammation
Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution
This study aims to evaluate whether dietary supplementation with fish oil can protect against the cardiopulmonary alterations linked to air pollution
- Conditions
- Oxidative Stress, Inflammation, Blood Pressure, Vasoconstriction
- Trial name
- NCT03255187
- Testing
- Fish oil supplementation, Sunflower seed oil supplementation
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fudan University
Relapsing-Remitting Multiple Sclerosis
Supplementation of VigantOL® Oil Versus Placebo as Add-on in Patients With Relapsing Remitting Multiple Sclerosis Receiving Rebif® Treatment
The drug being tested is called VigantOL® oil - a very effective form of Vitamin D hormone supplement (cholecalciferol). Low levels of Vitamin D have been described to be associated with a higher risk of developing Multiple…
- Trial name
- SOLAR (NCT01285401)
- Testing
- VigantOL oil plus interferon beta-1a (Rebif), Interferon beta-1a (Rebif®) alone
- Where
- 38 sites in Austria, Denmark and 10 more
- Volunteers
- 260 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Rheumatoid Arthritis
N-3 PUFA and Rheumatoid Arthritis in Korea
The purpose of this study is to see if supplementation of n-3 polyunsaturated fatty acid (PUFA) can be beneficial for the patients with rheumatoid arthritis.
- Trial name
- NCT01618019
- Testing
- Omega-3 fatty acid
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Hanyang University
Hypovitaminosis D
Comparing a Novel Phototherapy Kiosk to Oral Vitamin D Supplementation
The purpose of this project is to demonstrate the capability of a standing phototherapy kiosk (SPK) to stimulate cutaneous vitamin D3 and subsequent production of 25 Hydroxyvitamin (OH) D safely and as efficiently as an oral…
- Trial name
- NCT04556136
- Testing
- Standing Phototherapy Kiosk, D3 Oral supplement
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Malocclusion, Class II Buccal Segment Relationship
Chesterfield Micro-implant Study Involving Three Types of Anchorage Methods in Orthodontics
Research problem: Anchorage reinforcement is effective with headgear provided patient compliance is optimal. Nance palatal arch have also been shown to be effective.
- Trial name
- PJSPhD (NCT00995436)
- Testing
- Extraoral anchorage, Miniscrews, Nance
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Chesterfield and North Derbyshire Royal Hospital
Body Weight Changes, Athletic Performance
Whey Protein Supplementation in High School Athletes
The overall aim of this project is to compare protein supplementation on performance, recovery, and body composition changes in adolescent soccer players between the whey protein and the control group in response to the…
- Conditions
- Body Weight Changes, Athletic Performance, Recovery, Sleep
- Trial name
- NCT05589129
- Testing
- Whey Protein Supplement
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Utah
Post-Menopausal Osteoporosis, Post-Menopausal Osteopenia
Vitamin K Supplementation in Post-Menopausal Osteopenia
The purpose of this study is to determine whether supplementation with 5 mg vitamin K daily over a 2-year period will prevent bone loss in post-menopausal women with osteopenia.
- Trial name
- NCT00150969
- Testing
- vitamin K1 (phylloquinone)
- Where
- 5 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto