Clinical trials: Dietary Supplementation
Periodontal Diseases
Non-surgical Treatment of Chronic Periodontitis With an Adjunctive Vitamin E and Coenzyme Q10 Supplementation
Non-surgical treatment of chronic periodontitis with vitamin E and coenzyme Q10 supplementation
- Trial name
- NCT06373848
- Testing
- Receive 30 mg of Coq10
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome
Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure
The purpose of this study is to determine if choline bitartrate can be administered daily to children with prenatal alcohol exposure, ages 2.5 to 5, as a potential treatment for brain development and cognitive functioning.
- Conditions
- Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol Related Neurodevelopmental Disorder
- Trial name
- NCT01149538
- Testing
- Choline bitartrate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Diabetes, Low Muscle Mass
Exercise and/or HMB in Older Diabetes With Low Muscle Mass
The investigators aimed to examine if β-hydroxy-β-methylbutyrate (HMB) supplementation enhances the effects of exercise on muscle mass, physical performance and insulin resistance and observe potential residual effects in older…
- Trial name
- NCT07142941
- Testing
- HMB, Exercise, Education
- Volunteers
- 120 people
- Sponsor
- Wu Shangling
Hypoxia, Exogenous Ketosis
The Effects of Ketone Ester Supplementation During a 5 Week Live High, Train Low Altitude Training Camp
This study aims to investigate the effects of post-exercise and pre-sleep exogenous ketosis via oral ketone ester supplementation during a 5 week simulated altitude training camp.
- Trial name
- NCT06596083
- Testing
- Ketone ester supplement
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Menopause, Exercise Adaptation
The Effects of Menopausal Status, Isoflavone Supplementation and Training on Cardiometabolic Function Women
The goal of this clinical trial is to investigate the role of estrogen and isoflavone supplementation in exercise-induced cellular signaling and cardiometabolic adaptations in premenopausal and postmenopausal women.
- Conditions
- Menopause, Exercise Adaptation, Mitochondrial Alteration, Vascular Function in Healthy Volunteers
- Trial name
- EXISO (NCT07878741)
- Testing
- Red Clover Isoflavone Supplementation, Supervised exercise training
- Where
- 2 sites in Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Depression, Anxiety
The Influence of Probiotic Supplementation on the Severity of Anxiety and Depressive Symptoms, as Well as the Function and Composition of Gut Microbiota, Metabolic, Inflammation, and Oxidative Stress Markers in Patients With Depression
The aim of this study is to gather empirical evidence which will enable to evaluate the impact of probiotic supplementation on the severity of anxiety and depressive symptoms, function, and composition of gut microbiota…
- Trial name
- NCT05717946
- Testing
- Probiotic composed of two bacteria strains: Lactobacillus helveticus Rosell and Bifidobacterium longum Rosell., control group
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Depression, Anxiety
Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance
This study is aimed to investigate if Lemon Balm Extract supplementation is beneficial for the relief of stress, depression and anxiety in healthy adults.
- Conditions
- Depression, Anxiety, Stress, Insomnia
- Trial name
- NCT05602688
- Testing
- Lemon Balm Supplement
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ayub Teaching Hospital
Diarrhea, Respiratory Infection
Impact of Zinc Supplementation in Low Birth Weight Infants on Severe Morbidity, Mortality and Zinc Status: A Randomized Controlled Trial
There are currently no interventions available to substantially reduce the incidence of low birth weight (LBW) apart from increasing the age at marriage, maternal iron supplementation and possibly improved energy intakes.
- Conditions
- Diarrhea, Respiratory Infection, Low Birth Weight
- Trial name
- NCT00272142
- Testing
- Zinc
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Endometriosis
Effect of Quercetin Supplementation on Endometriosis Outcomes
Quercetin is a polyphenol compound that possesses anti-inflammatory properties and can be found in various food sources like apples, berries, cabbage, and onions.
- Trial name
- NCT05983224
- Testing
- Quercetin
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- National Nutrition and Food Technology Institute
Non Alcoholic Fatty Liver Disease (NAFLD)
Potential Role of n-3 Fatty Acids in the Treatment of NAFLD in Pediatric Patients
Nonalcoholic hepatic steatosis (NASH) is defined as the amount greater than 5% of the total liver volume fat. Commonly known as NASH, it includes 4 stages histological ranging from the mere presence of fat to the existence of…
- Trial name
- NCT02201160
- Testing
- omega 3
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- St. Justine's Hospital
Muscle Strength
The Effects of Ashwagandha (Withania Somnifera) Supplementation on Exercise Performance in Female Footballers
The goal of this clinical trial is to evaluate the effects of short-term root extract ashwagandha supplementation on exercise performance in female footballers.
- Trial name
- NCT06264986
- Testing
- Ashwagandha
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Blanca Roman-Viñas, MD
Healthy Adult Participants, Vitamin D Insufficiency
Supplementation of Cholecalciferol and Related Active Metabolites Through Bioenhancing Layer's Eggs
The purpose of this research is to evaluate if 1) consumption of vitamin D3- or 25(OH)D3-biofortified eggs will increase vitamin D and 25(OH)D status in young adults who consume these bioenhanced eggs, 2) to determine if the gut…
- Trial name
- SCRAMBLE (NCT07859280)
- Testing
- Vitamin D3 bioenhanced eggs, 25(OH)D3 bioenhanced eggs
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cornell University
Liver Cirrhosis
Branched Chain Aminoacid Supplementation in Patients With Liver Cirrhosis
Malnutrition is a frequent complication in patients with liver cirrhosis. Most patients have decreased dietary intake due to ascites, hepatic encephalopathy and pro-inflammatory cytokines.
- Trial name
- NCT02023229
- Testing
- Branched-chain aminoacids, High-fiber high protein diet
- Where
- Mexico
- Volunteers
- 68 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Cell Migration, Cell Invasion
This Repeated Measures Parallel-group Investigation Will Examine the Influence of Short-term Melatonin Supplementation (5mg, 3 x Day for 72 Hours) on Cellular Responses, Functional Performance and Recovery Following an Acute Bout of Dynamic Resistance Exercise in Resistance Trained Men and Women
Oral Melatonin is a commercially available product available alone and as a constituent in a number of supplements. Previous research suggests that short-term supplementation with oral melatonin may amplify the recovery response…
- Conditions
- Cell Migration, Cell Invasion, Exercise Recovery
- Trial name
- NCT06617351
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Estrogen Supplementation
The Anabolic Effects of Estrogen on Skeletal Muscles
Purpose: to study the effect of estrogen replacement on muscle hypertrophy in response to 12 weeks resistance training in postmenopausal women Hypothesis: Transdermal administration of 17-β estradiol enhance the anabolic effect…
- Trial name
- ESTRO (NCT03020953)
- Testing
- Exercise + Estrogen
- Where
- Denmark
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type 1 Diabetes Mellitus
Effect of 4 Weeks of Oral Probiotic Desulfovibrio Piger Supplementation on Immunological and Metabolic Parameters in Individuals With Longstanding Type 1 Diabetes
The goal is to establish the effect of oral probiotic Desulfovibrio piger (D. piger) supplementation on immunological and metabolic parameters in individuals with longstanding type 1 diabetes with residual beta cell function.
- Trial name
- PROSPER (NCT07585994)
- Testing
- Probiotic dietary supplement
- Where
- 2 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Skin
A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Nutritional Supplement Lumenato and Its Impact on Skin Parameters in Healthy Female Subjects
The purpose of this study is to evaluate perceived changes in skin health and appearance after taking the study product daily for 12 weeks. The study product is a soft gel supplement containing tomato oil.
- Trial name
- NCT04356456
- Testing
- Lumenato
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- LycoRed Ltd.
Attention Deficit Hyperactivity Disorder, Healthy
The Effects of EPA/DHA Supplementation on Cognitive Control in Children With ADHD
Forty children with and 40 children without Attention deficit Hyperactivity Disorder (ADHD) receive Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) or placebo via a dietary intervention.
- Trial name
- NCT01554462
- Testing
- Eicosapentaenoic acid / Docosahexaenoic acid
- Where
- Netherlands
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Dry Eye Syndrome (DES)
Dietary Supplementation on Tear Secretion and Inflammation in DES
The goal of this clinical trial is to explore the effect of supplementation of fish oil, lutein and zeaxanthin on the symptoms of dry eye syndrome, antioxidant capacity, oxidative stress and anti-inflammatory capacity in DES…
- Trial name
- DES (NCT06738446)
- Testing
- Multicomponent dietary supplement group
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- Shih Chien Huang
Osteoporosis, Aging
Vitamin D Supplementation in Older Women
The purpose of this study is to examine the effects of several doses of vitamin D on hormones related to bone, calcium absorption, bone density and muscle strength.
- Trial name
- VIDOS (NCT00472823)
- Testing
- Vitamin D3, Calcium Citrate (Citracal)
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- Creighton University
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