Clinical trials: Dietary Supplementation
Frail Elderly
Synergy of Exercise and Nutrition in Preventing and Treating Frailty
The goal of this clinical study is to learn if combining a nutritional supplement with a multicomponent exercise program can help prevent and treat frailty in community dwelling older adults.
- Trial name
- ROBUSTNES (NCT06975540)
- Testing
- Multidomain physical exercise
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Female Hormone Profile
Acute Vitamin D Supplementation on Testosterone in Females
Participation will take place over two visits to the Clinical Exercise Research Center (CERC) at the University of Southern California Health Sciences Campus.
- Trial name
- NCT06610968
- Testing
- Vitamin D (Cholecalciferol )
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Transthyretin Cardiac Amyloidosis
EFICAC-TTR Trial: Exercise and Nutritional Supplementation in Transthyretin Cardiac Amyloidosis
Transthyretin cardiac amyloidosis (TTR-CA) is a systemic cardiac disease that predominantly affects older adults and is frequently associated with reduced physical capacity, muscle weakness, frailty, and impaired quality of life.
- Trial name
- EFICAC-TTR (NCT07343999)
- Testing
- Home-Based Multicomponent Exercise Program, Microcrystalline Cellulose Control Supplementation, Creatine and HMB Supplementation
- Where
- 3 sites in Spain
- Volunteers
- 47 people
- Sponsor
- Universidad de Burgos
Heart Failure, Systolic, Iron-deficiency Anemia
Short Term Oral Iron Supplementation in Systolic Heart Failure Patients Suffering From Iron Deficiency Anemia
The purpose of this study is to determine the efficacy of Ferrous Sulphate (FS) tablets in improving iron stores and functional capacity in HF patients with Iron Deficiency Anemia (IDA).
- Trial name
- IRON5 (NCT02998697)
- Testing
- Ferrous Sulfate
- Volunteers
- 54 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Covid19
Evaluation of a Probiotic Supplementation in the Immune Response of Participants With COVID-19 (Coronavirus Disease).
An interventional, randomized, double-blind, placebo-controlled study will be conducted to investigate the effect of a probiotic strain on the immune response in participants positive for SARS-CoV-2 infection.
- Trial name
- PROVID (NCT04937556)
- Testing
- Probiotic: Lactobacillus salivarius + Vit D + Zinc
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- ProbiSearch SL
Thrombosis
Evaluation of Factors II, VII, IX, X, and Proteins C and S, Following High-dose Vitamin K Supplementation
The purpose of this study is to evaluate factor levels of the pro coagulant factors II, VII, IX, X, and the anticoagulant factors protein C and S in healthy volunteers during the intake of elevated levels of vitamin K in order to…
- Trial name
- NCT01143831
- Testing
- Vitamin K, 20mg
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stephan Moll, MD
Resistance Training, Muscle Damage
Protein Supplementation and Recovery of Muscle Function
The focus is performance nutrition. Resistance exercise can induce low level muscle damage in conjunction with impaired contractile function.
- Trial name
- NCT03297151
- Testing
- CONTROL, Whey Protein Concentrate, Whey Protein Hydrolysate
- Where
- Ireland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Pre-diabetes
Anti-hyperglycemic Effect of Short-term Arginyl-fructose Supplementation in Subjects With Pre-diabetes and Newly Diagnosed Type 2 Diabetes: Randomized, Double-blinded, Placebo-controlled Trial.
In this double-blind, placebo-controlled study, subjects with prediabetes and type 2 diabetes were randomly assigned to the placebo control group or the test (Arginyl-fructose: AF) group.
- Trial name
- NCT02285231
- Testing
- Arginyl-fructose
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Vitamin D Deficiency, Osteopenia of Prematurity
The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants.
The aim of this study will be to assess the effectiveness of monitored vit D supplementation in a population of preterm infants and to identify whether the proper vit D supplementation in preterm infants can reduce the incidence…
- Conditions
- Vitamin D Deficiency, Osteopenia of Prematurity, Nephrolithiasis, Metabolic Bone Disease
- Trial name
- HIDVID (NCT06199102)
- Testing
- cholecalciferol/ Devikap
- Where
- Poland
- Volunteers
- 130 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Wound Healing, Diabetic
Effect of Supplementation With HMB and Glutamine in Wound Healing on Bloody Areas
A randomized controlled clinical trial in two groups of supplementation with HMB and glutamine. Each group consist in 25 patients with bloody areas, one group will receive and intervention with HMB and Glutamine and the other…
- Trial name
- NCT03782155
- Testing
- glutamine supplementation, HMB
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Hospital General de Mexico
Cardiovascular Disease, Diabetes Mellitus
Living With Statins - Interventional Exercise Study
Background. Statins are cholesterol lowering drugs that are prescribed to lower the risk of cardio-vascular diseases. The use of statins has increased markedly and it is now one of the most prescribed drugs in the world.
- Trial name
- LIFESTAT (NCT02796378)
- Testing
- Training+Simvastatin+Q10
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Fatigue, Metastatic Prostate Carcinoma
Resistance Training +/- Creatine for Metastatic Prostate Cancer Patients
This trial studies how well resistance training with or without creatine monohydrate supplement works in improving body composition and health outcomes in patients with prostate cancer that has spread to other places in the body.
- Conditions
- Fatigue, Metastatic Prostate Carcinoma, Sedentary Lifestyle, Stage IV Prostate Cancer AJCC (American Joint Committee on Cancer) v8
- Trial name
- NCT03987217
- Testing
- Creatine Monohydrate, Exercise Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Utah
Hip Fractures, Fragility Fracture
Iron Supplementation for Geriatric Hip Fractures
Geriatric hip fracture is an important disease that affects the health life of the elderly in China. Geriatric hip fracture is often complicated by a variety of comorbidities due to advanced age.
- Conditions
- Hip Fractures, Fragility Fracture, Osteoporotic Fractures
- Trial name
- NCT05489952
- Testing
- iron sucrose and ferrous lactate
- Where
- China
- Volunteers
- 444 people
- Sponsor
- He Qifei
Muscle Damage
Effect of Branched-chain Amino Acid Supplementation on Muscle Damage
Seventy-eight recreational athletes who never resistance trained will be randomly assigned into three groups of twenty-six. Branched-chain amino acid will be supplemented for 18days at 0, 200 or 400 mg/body weight(kg)/day in…
- Trial name
- NCT03766815
- Testing
- BCAA 200mg/kg/day, BCAA 400mg/kg/day, Muscle damaging exercise
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Dry Eye Syndromes, Celiac Disease
Omega-3 Fatty Acid Supplementation and Tear Film Quality in Celiac Patients
The study aims to determine the effectiveness on the tear film quality and symptoms related with dry eye disease in patients with celiac disease.
- Trial name
- OmegaCelDED (NCT05825976)
- Testing
- Omega-3 Fatty ACids, Control
- Where
- Bosnia and Herzegovina
- Volunteers
- 45 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Diabetes Mellitus, Chronic Periodontitis
Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics
Therefore, the aim of this study is to investigate the effectiveness of daily supplementation of omega-3 polyunsaturated fatty acids and low-dose aspirin as adjunct therapy to one-stage full-mouth periodontal ultrasonic…
- Trial name
- NCT02800252
- Testing
- 3g omega-3 plus 100mg aspirin daily for 60 days, omega-3 plus aspirin before periodontal therapy
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Diabetes Mellitus
The Effect of 2 Grams Daily Supplementation of Sativa Nigra Oil on Blood Glucose Levels of Adults.
Diabetes mellitus is a growing global concern with significant health and financial burdens. The Kingdom of Saudi Arabia is one of the world's top 10 countries with the highest diabetes prevalence.
- Trial name
- NCT03776448
- Testing
- Sativa Nigra oil Softgels, Activated Charcoal Softgels
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sulaiman AlRajhi Colleges
Covid19, Acute Respiratory Tract Infection
Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections
CORONAVIT is an open-label, phase 3, randomised clinical trial testing whether implementation of a test-and-treat approach to correction of sub-optimal vitamin D status results in reduced risk and/or severity of COVID-19 and…
- Trial name
- CORONAVIT (NCT04579640)
- Testing
- Vitamin D
- Where
- United Kingdom
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Physical Inactivity
Blood Flow Restriction and Creatine Supplementation in Women
This research is examining the changes in muscle size, muscle function, body composition, strength, and blood vessel health. Specifically, the changes in these variables over the course of 8 weeks of training with or without…
- Trial name
- NCT05877417
- Testing
- Creatine Monohydrate, Blood Flow Restriction, Exercise
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Sarcopenia
HMB Supplementation and Motor Performance in Sarcopenic Patiens
Aging is often accompanied by the reduction and weakening of muscle mass, a condition defined as sarcopenia. According to the most recent criteria from the European Working Group on Sarcopenia in Older People, sarcopenia is…
- Trial name
- HMB-SARC (NCT06801808)
- Testing
- Myosave
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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