Clinical trials: Dietary Supplementation
Muscle Weakness, Osteoporosis, Postmenopausal
Assessing the Effect of Shatavari Supplementation on Bone and Skeletal Muscle Health in Healthy Postmenopausal Women
Shatavari is a plant that grows in Nepal, Sri Lanka, India and the Himalayas and its root has long been used in Ayurvedic medicine.
- Trial name
- NCT05025917
- Testing
- Shatavari, Magnesium stearate
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Retinitis Pigmentosa
Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa
To determine whether supplements of vitamin A or vitamin E alone or in combination affect the course of retinitis pigmentosa.
- Trial name
- NCT00000114
- Testing
- Vitamin E, Vitamin A
- Sponsor
- National Eye Institute (NEI)
Copd
Oral Supplementation During PR Participation in COPD
Chronic obstructive pulmonary disease (COPD) is a very common and chronic lung condition and is a leading cause of morbidity and death.
- Trial name
- NCT06324214
- Testing
- Urolithin A (Mitopure)
- Where
- 3 sites in Canada
- Volunteers
- 22 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Healthy
Pharmacokinetic Study: Effect of 25(OH)D and Vitamin D3 on Serum 25(OH)D
We compare the effect of HyD (25-hydroxyvitamin D) and vitamin D3 in their effect on 25-hydroxyvitamin D plasma levels over a course of 4 month. This is a pharmacokinetic study including 35 postmenopausal women.
- Trial name
- NCT00718276
- Testing
- 25(OH)D, vitamin D3
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Congenital Heart Disease (CHD)
Impact of Vitamin C Supplementation on Hospital Outcomes in Children Undergoing Corrective Heart Surgery for Congenital Heart Diseases
Vitamin C will be given before admission in the immediate preoperative preceding 7 days (the dose 30 -45 mg per day ) in oral drops preparations Inflammatory markers including CRP , TLC ,PNI , GPS NLR will be checked on admission…
- Trial name
- RCT (NCT06789640)
- Testing
- Vitamin C
- Volunteers
- 20 people
- Sponsor
- Cairo University
Athletic Performance, Cognitive Fatigue
TCP-600 Supplementation and Performance Response in Professional Football Players
This study will examine whether a 28-day supplementation protocol containing taurine, caffeine, and phosphatidylserine can help professional male football players maintain physical performance, cognitive function…
- Conditions
- Athletic Performance, Cognitive Fatigue, Exercise Recovery, Football-Specific Performance
- Trial name
- TCP600-RESP (NCT07710547)
- Testing
- Taurine, Caffeine, Phosphatidylserine
- Where
- 3 sites in Poland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vizja University in Warsaw
Pre-diabetes
Supplementation of YMETA, on Gut Health, Immunity and Metabolism in Pre-diabetic Adult Population
Type 2 diabetes mellitus (T2DM) is a major non-communicable disease and one of the world's fastest growing health problems. According to a 2019 report, about 463 million adults worldwide currently have diabetes and future…
- Trial name
- YMETA (NCT05400525)
- Testing
- YMETA
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Roehampton
Sarcopenia
Omega-3 Supplementation in Cervix Cancer Patients Undergoing Chemoradiotherapy
Cancer cachexia is a complex metabolic process affecting up to 80% of patients suffering from an advanced-stage cancer. Moreover, 20 to 40% of all cancer deaths are caused directly by cachexia.
- Trial name
- NCT02779868
- Testing
- Omega-3, Olive oil
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Brazilian National Cancer Institute
Long COVID
Mental Intervention and Nicotinamide Riboside Supplementation in Long Covid
Long COVID, also referred to as post-acute sequela of COVID-19 (PASC), is present in a substantial number of individuals, and treatment for this is warranted.
- Trial name
- MINIRICO (NCT05703074)
- Testing
- Nicotinamide Riboside (NR), Mind-body reprocessing therapy (MBRT), Care as usual
- Where
- Norway
- Volunteers
- 310 people
- Sponsor
- University Hospital, Akershus
Metabolic Syndrome
Effects of Oral Fruit Concentrate Supplementation on Cardiometabolic Parameters.
Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount.
- Trial name
- NCT04177238
- Testing
- Fruit concentrate - either cherry or blueberry
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Bladder Cancer, Entire Ileal Conduit
Prehabilitation to Enhance Postoperative Functional Capacity Following Radical Cystectomy
The process of enhancing the functional capacity of an individual before an operation to enable him or her to withstand the stress of surgery has been termed prehabilitation.
- Conditions
- Bladder Cancer, Entire Ileal Conduit, Urinary Bladder Cancer
- Trial name
- NCT01836978
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Clozapine Resistant Schizophrenia
Vitamin D for Schizophrenia
Background: Despite improvements in medications, treatment delivery and rehabilitation, schizophrenia outcomes remain suboptimal. There are a proportion of 30-40% treatment-resistant schizophrenia patients.
- Trial name
- NCT01759485
- Testing
- Vitamin D3
- Where
- Israel
- Volunteers
- 47 people
- Sponsor
- Geha Mental Health Center
Constipation, Diarrhea
Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population
The purpose of this study is to investigate the effect of a daily supplement consisting of the probiotic bacteria, Lactobacillus reuteri, on the digestive health among persons 65 years and older.
- Conditions
- Constipation, Diarrhea, Indigestion, Reflux
- Trial name
- NCT01837940
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Sweden
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Glucose Metabolism Disorders, Overweight or Obesity
Metabolic Effects of Oral Sodium Butyrate Supplementation on Overweight Individuals
Numerous evidences suggest an important role of short-chain fatty acids, produced by the intestinal fermentation of dietary fibers by the intestinal microbiota, in the modulation of various biological functions relevant to human…
- Trial name
- NCT06247020
- Testing
- Supplementation with sodium- butyrrate
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Federico II University
Incremental Haemodialysis
INCREmental DIalysis and Diet for a Better Life Experience
Previous studies suggest that the supplementation of essential amino acids and ketaoacids may prolong the duration of the incremental phase of peritoneal dialysis. There is no data on incremental haemodialysis patients.
- Trial name
- INCREDIBLE (NCT07699627)
- Testing
- Supplementation by ketosteril
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier le Mans
Obesity and Overweight
Plant-Based Foods and (Poly)Phenol Supplementation in Gut Microbiota Modulation, Body Weight, and Cardiometabolic Risk
This single-blind, randomized controlled trial aims to evaluate the effects of increased dietary polyphenol intake-either through a healthy plant-based diet (PBD) or supplementation-on body weight and cardiometabolic risk factors…
- Trial name
- PREDIET-ARAC (NCT06911346)
- Testing
- Diet supplementation, Polyphenol-rich supplement
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Universidad Catolica de Temuco
Cardiovascular Risk Factor
Short Term Ketone Supplementation and Cardiometabolic Health
The purpose of this research study is to determine if short-term consumption of a dietary ketone drink, which increases the blood circulation concentrations of beta-hydroxybutyrate, a ketone, affects blood vessel health and…
- Trial name
- NCT04236388
- Testing
- Ketone drink
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Heart Failure
Dietary Supplementation in Heart Failure
A single-center, double-blind, placebo-controlled, cross-over study pilot study comparing R Drink vs. placebo in 60 heart failure patients. Half of the participants will also have diabetes mellitus.
- Trial name
- R-DRINK (NCT03980574)
- Testing
- R Drink
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ohio State University
Critically Ill
Protein Supplementation vs Standard Feeds in Underweight Critically Ill Children: A Dual-Centre Pilot RCT
This pilot trial is part of a long-term research program leading to a large trial to determine if a strategy of supplementing protein in a subset of critically ill children is superior to standard enteral nutrition care.
- Trial name
- NCT04565613
- Testing
- Enteral protein supplementation
- Where
- Singapore
- Volunteers
- 34 people
- Sponsor
- KK Women's and Children's Hospital
ADHD
Probiotic Supplementation in Children With ADHD
This randomised, placebo controlled trial explores the effects of supplementation with a probiotic drink (kefir) in children diagnosed with ADHD on behaviour, sleep, attention and the gut microbiome.
- Trial name
- NCT05155696
- Testing
- Experimental: Kefir probiotic drink (supplied by Nourish)
- Where
- United Kingdom
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
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