Clinical trials: Dietary Supplements
Osteoporosis, Vascular Calcification
Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification
The purpose of this study is to determine if supplemental vitamin K will reduce age-related bone loss in elderly men and women above that achieved by supplementation.
- Conditions
- Osteoporosis, Vascular Calcification, Inflammation
- Trial name
- NCT00183001
- Testing
- Vitamin K
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Cognition, Muscle Strength
Dietary Supplements and Middle Aged Women (Creatine)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Muscle Strength, Fatigue Symptom, Blood Pressure and Augmentation Index
- Trial name
- NCT07729930
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Postoperative Recovery, Total Knee Arthroplasty
Nutrition and Swelling
This study is looking at whether taking a nutritional supplement before and after knee replacement surgery affects normal recovery.
- Trial name
- NCT07899762
- Testing
- Xcelerated Recovery Nutritional Supplement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Premature Infant, Low Birthweight Infant
Feeding Tolerance and Growth of Preterm Infants Consuming a Supplement Containing Two Human Milk Oligosaccharides (HMOs)
The goal of this post-market study is to describe the effect of a liquid supplement containing 2 specific human milk oligosaccharides (HMOs), 2'-fucosyllactose [2'FL] and lacto-N-neotetraose [LNnT], on feeding tolerance, growth…
- Trial name
- NCT06212427
- Testing
- HMO supplement
- Where
- 6 sites in Austria, Germany
- Volunteers
- 188 people
- Sponsor
- Société des Produits Nestlé (SPN)
Lung Cancer, Gastro-Intestinal Cancer
Whey Protein Supplement in Combination With Physical Exercise and Nutrition Program
This study evaluates physical performance in cancer outpatients during a multimodal therapy. Half of the patients will receive physical exercise und nutrition program in combination with a specially formulated whey protein…
- Conditions
- Lung Cancer, Gastro-Intestinal Cancer, Breast Cancer, Prostate Cancer
- Trial name
- NCT02585362
- Testing
- physical exercise, nutrition counseling, whey protein supplement
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Kantonsspital Winterthur KSW
Healthy
Flavonoid Supplementation and Endothelial Function
Flavonoids are one of the many classes of natural chemicals found in a variety of foods. People with the highest flavonoid blood levels have the lowest rates of coronary heart disease.
- Trial name
- NCT00331227
- Testing
- Isotonix OPC-3 (flavonoid supplement)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Stroke, Ischemic Stroke
Dietary Nitrate Supplements and Ischemic Stroke Recovery
This is a double-blind, randomized, placebo-controlled, pilot study. Participants will be randomized to receive either beetroot juice or a beetroot juice placebo, as a dietary supplement, for 30 days.
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Accident
- Trial name
- NCT02838901
- Testing
- Beet it Beetroot juice
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
Immunity Disorders, Aging
The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age
This is a prospective, interventional, single-arm, open-label pilot study of 50 patients to evaluate the effect of a polyphenol-rich nutritional supplement on epigenetic and cellular markers of immune age.
- Conditions
- Immunity Disorders, Aging, Inflammation
- Trial name
- NCT05234203
- Testing
- HTB Rejuvenate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Big Bold Health, PBC
Incident Breast Cancer
Green Tea in Breast Cancer Patients
Prognostic factors for breast cancer beyond stage at diagnosis and tumor characteristics have not been well studied. Of special interest are lifestyle factors that can be modified by women after diagnosis to increase disease-free…
- Trial name
- NCT00949923
- Testing
- tea capsule
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Southern California
Down Syndrome, Fragile X Syndrome
Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS)
To evaluate safety and tolerability of epigallocatechin gallate (EGCG) in children from 6 to 12 years old with Intellectual Developmental Disorders (IDD) (Down syndrome or Fragile X syndrome).
- Trial name
- PERSEUS (NCT03624556)
- Testing
- EGCG FontUp
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- Parc de Salut Mar
Pregnancy, Autistic Disorder
Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children
The purpose of this research study is to screen for metabolic abnormalities that are maternal risk factors for having a child with autism.
- Conditions
- Pregnancy, Autistic Disorder, Folic Acid Deficiency
- Trial name
- NCT02674022
- Testing
- Prenatal supplement
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Malnutrition
Nutrition Supplementation in Hospitalized Patients
Patients with severe malnutrition risk are 7.4 times more likely to die in hospital than well-nourished patients, and carry a 30-day readmission rate of >46%.
- Trial name
- NutriSuP (NCT02632630)
- Testing
- Amino Acids w/Electrolytes in Dextrose, Ensure product, Crystalloid solutions
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Healthy, Aging
Safety, Tolerability, and Pharmacokinetics of an Oral Withania Somnifera Product in Older Adults
This study will measure the oral bioavailability and pharmacokinetics of known compounds from a standardized Withania somnifera botanical dietary supplement in healthy older adults.
- Trial name
- NCT07008300
- Testing
- Shoden
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chronic Obstructive Pulmonary Disease(COPD), Malnutrition
Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD
Insufficient energy intake and systematic inflammation lead to malnutrition in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02197871
- Testing
- enteral nutrition emulsion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhujiang Hospital
HDL, Health, Subjective
HDL Function Dietary Supplement Safety and QOL
Nutritional supplements are routinely purchased by consumers with suboptimal HDL to support their health, lifestyle and overall quality of life. Many such products receive minimal evaluation prior to marketing.
- Trial name
- NCT04097119
- Testing
- Dietary supplementation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Growth and Development
To Investigate the Impact of a Nutritional Supplement on Bone Turnover Markers in Indian Healthy Premenopausal Women (25- 45 Years) After 6 Months of Intervention
To investigate the effect of nutritional supplement on bone turnover markers (which are sensitive and respond quickly to nutrition or drug intervention) in Indian healthy premenopausal women after 6 months of intervention.
- Trial name
- NCT03155269
- Testing
- Fortified Beverage Powder, Non fortified beverage Powder
- Where
- India
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tibial Fracture
Vitamin D Supplement for Patients With Tibial Fracture
The purpose is to study: 1. the frequency of vitamin D deficiency at patients with tibial fracture treated with an external ring fixator 2. if vitamin D supplement facilitates fracture healing 3.
- Trial name
- NCT01955577
- Testing
- Vitamin D3 cholecalciferol
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Alcoholic Liver Disease, COVID 19 Pneumonia
Study of HMB-enriched Amino Acid Supplementation in Patients With Alcoholic Liver Disease and COVID-19
Patients with COVID-19 and comorbidities including alcohol associated liver disease (ALD) are at risk for severe illness and abrupt or sudden clinical deterioration with ventilatory failure.
- Trial name
- NCT04858412
- Testing
- β-hydroxy β-methyl butyrate (HMB) enriched amino acid, Balanced amino acid
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The Cleveland Clinic
Overweight, Obesity
Vitamin D Effects in Overweight Patients
The purpose of the study is to investigate in overweight patients who are on a telemedically guided weight loss program the influence of a daily vitamin D supplement on weight loss and body composition, selected inflammation…
- Trial name
- SMART (NCT00493012)
- Testing
- vitamin D
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Breast Cancer Female, Pain, Postoperative
Effects of Bromelain and Boswellia Serrata Casperome With Centella Asiatica and Vitamins on Edema, Paresthesia and Postoperative Pain After Quadrantectomy With or Without Sentinel Lymph Node Biopsy.
Aim: to investigate the effects of dietary supplements on postoperative edema and pain in patients undergoing quadrantectomy for breast cancer.
- Trial name
- NCT04669119
- Testing
- Bromelain/Boswellia Serrata Casperome, Centella Asiatica/Vitamins
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Bari Aldo Moro