Clinical trials: Dietary Zinc Deficiency
Zinc Deficiency, Dyslipidemias
Zinc Supplement Before or With Food in Generally Healthy Men
The purpose of this study is to determine the influence of food consumption timing on the body's response to a zinc supplement
- Conditions
- Zinc Deficiency, Dyslipidemias, Zinc Excess, Inflammation
- Trial name
- NCT03619421
- Testing
- Zinc supplement
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Zinc Deficiency
Water-based Zinc Efficacy Trial in Beninese Shool Children
The general objective of this study is to determine the effect of the daily consumption of zinc-fortified water provided by the LSF-filter on zinc status and diarrhea rates in school age children from rural areas characterized by…
- Trial name
- NCT01790321
- Testing
- LSF-filtering device
- Where
- Benin
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
Zinc Deficiency, Growth; Stunting, Nutritional
The Efficacy of Zinc-biofortified Rice in Bangladeshi Children
To assess the efficacy of the zinc biofortified rice on plasma zinc concentrations in infants from a rural area of Bangladesh.
- Trial name
- ZARI (NCT03079583)
- Testing
- Intervention-group, Control-group
- Where
- 2 sites in Bangladesh, Switzerland
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Human Immunodeficiency Virus (HIV)
A Phase I Study of T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728mR in HIV-Infected Patients
This is a triple cohort, open-label pilot study of the safety and antiviral activity of a single infusion of autologous CD4+ T cells genetically modified at the CCR5 gene by Zinc Finger Nucleases SB-728mR (ZFN Modified CD4+ T…
- Trial name
- NCT02388594
- Testing
- ZFN Modified CD4+ T Cells, Cyclophosphamide
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pennsylvania
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a Standard Dose
The overall objective is to determine the impact of EED on zinc absorption and homeostasis, and its impact on the absorptive capacity of vitamin A absorption of young children (18-24 months of age) in an austere setting with high…
- Conditions
- Environmental Enteric Dysfunction, Zinc Deficiency, Vitamin A Deficiency
- Trial name
- ZEED1 (NCT02760095)
- Testing
- 3 mg zinc sulfate supplement, 0.5 mg of 13C10-retinyl-acetate
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron Deficiency Anemia
Nutrient Fortified Oat Drink
This study will follow a randomized, double-blind, placebo-controlled, parallel-group design to test if an oat beverage fortified with iron, zinc vitamin A and vitamin C will improve nutrient status and iron deficiency in young…
- Trial name
- NCT01418898
- Testing
- Dietary Intervention
- Where
- Philippines
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Anemia, Iron Deficiency
Effectiveness of Iron-Fortified Milk on Iron Status and Anemia in Young Children in Mexico
Iron deficiency and anemia in infants and young children impair neurodevelopment. Efficacious interventions for reducing the prevalences of iron deficiency and anemia, under controlled conditions, are available.
- Conditions
- Anemia, Iron Deficiency, Stunting
- Trial name
- NCT00508131
- Testing
- Whole Cows Milk
- Where
- Mexico
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Zinc Deficiency
Impact of Targeted Zinc Fortification Programs on Plasma Zinc Concentration
The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of targeted zinc fortification programs.
- Trial name
- NCT00944398
- Testing
- Zinc fortified food, Zinc supplement, Non-fortified food
- Where
- Senegal
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Zinc Deficiency
A Randomized, Double-Blind, Placebo Controlled Study of NPC-02 in Patients With Zinc Deficiency
The objective of this study is to evaluate efficacy and safety of NPC-02 in patients with Zinc Deficiency.
- Trial name
- NCT02337569
- Testing
- NPC-02
- Where
- Japan
- Volunteers
- 57 people
- Sponsor
- Nobelpharma
HIV Infection, Alcohol Use
Zinc for HIV Disease Among Alcohol Users - an RCT in the Russia ARCH Cohort
This study is a double-blinded randomized controlled trial (RCT) to assess the efficacy of zinc supplementation vs. placebo among 250 HIV-infected Russians from the Russia ARCH Cohort, who are ART-naive at enrollment and have a…
- Trial name
- ZINC (NCT01934803)
- Testing
- Zinc gluconate
- Where
- Russia
- Volunteers
- 254 people
- Sponsor
- Boston Medical Center
HIV
Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients
The purpose of the study is to evaluate the safety and feasibility of administering SB-728mR-HSPC after conditioning with busulfan.
- Trial name
- NCT02500849
- Testing
- SB-728mR-HSPC Infusion 3 days following busulfan conditioning
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- City of Hope Medical Center
HIV Infections
Safety and Efficacy of Zinc Supplementation in HIV-1-Infected Children in South Africa
The goal of the study is to rule out a harmful effect of zinc supplementation in HIV-1-infected children. The null hypothesis is that zinc supplementation will increase plasma HIV RNA levels.
- Trial name
- NCT00138047
- Testing
- zinc supplementation
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV Infections
Trial of Zinc and HIV Progression in Children
To examine whether daily oral zinc supplementation to HIV-infected Tanzanian preschool children reduces diarrheal and respiratory morbidity, delays HIV disease progression, and improves growth.
- Trial name
- NCT00446758
- Testing
- Zinc
- Where
- Tanzania
- Volunteers
- 440 people
- Sponsor
- Harvard School of Public Health (HSPH)
Vitamin A Deficiency, Iron Deficiency
Effect Of Multiple Biofortified Food Crops On Micronutrient Status And Immune Function Among Indian Infants and Their Mothers
In this study, meals based on multiple food crops (containing either biofortified or commercially-available food crops) will be fed to young children in Madanapalle, Andhra Pradesh, India over a period of nine months to measure…
- Conditions
- Vitamin A Deficiency, Iron Deficiency, Zinc Deficiency
- Trial name
- MBFC (NCT02648893)
- Testing
- Multiple biofortified food crops (MBFC-Exp), Commercially available non-fortified food crops (MBFC-C)
- Where
- 2 sites in India
- Volunteers
- 200 people
- Sponsor
- Cornell University
Zinc Deficiency, Sars-CoV-2 Infection
Zinc Supplementation Impact in Acute COVID-19 Clinical Outcomes
Infections with SARS-CoV-2 result in a systemic disease with a variety of outcomes, from no symptoms to severe and diverse pathologies.
- Trial name
- MARZINC (NCT05778383)
- Testing
- Zinc Acetate
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Parc de Salut Mar
Sickle Cell Disease, Zinc Deficiency
Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya
Zinc is a nutritionally essential trace element found in previous studies to reduce growth retardation and improve immune function, which may also result in decreased incidence of infectious diseases including malaria, pneumonia…
- Conditions
- Sickle Cell Disease, Zinc Deficiency, Infection
- Trial name
- NCT03293641
- Testing
- Zinc Sulfate Tablets, Standard of Care
- Volunteers
- 40 people
- Sponsor
- Lucas Otieno Tina, MD MSc