Clinical trials: Difference, Individual
Healthy, Obesity
A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Japanese Healthy People and Japanese People With Obesity or Overweight
Part 1: To investigate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of BI 3034701 in Japanese male and female participants with body mass index (BMI) ≥27.0 kg/m² or more following subcutaneous…
- Trial name
- NCT07693231
- Testing
- BI 3034701
- Where
- 3 sites in Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 1
A Research Study of How Different Amounts of a New Medicine NNC0148-0287 C (Insulin 287) Works on the Blood Sugar of People Who Are Japanese With Type 1 Diabetes When Given Once a Week
This study will look at how insulin 287 works, if it is safe and the side effects in people who are Japanese with type 1 diabetes.
- Trial name
- NCT03766854
- Testing
- insulin icodec, Insulin glargine U100
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Novo Nordisk A/S
Fall Prevention, Exercise
Comparison of a Group-delivered vs. Individually Delivered 'LiFE' Program
In the Lifestyle-Integrated Functional Exercise (LiFE) program, exercises to increase strength and improve balance are embedded into daily life activities.
- Trial name
- LiFE-is-LiFE (NCT03462654)
- Testing
- iLiFE, gLiFE
- Where
- 2 sites in Germany
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Healthy
A Study in Healthy People to Compare 2 Different Formulations of BI 1015550 Taken With or Without Food
The main objective of this trial is to investigate the relative bioavailability of BI 1015550 intended Commercial Formulation (iCF) compared with Trial Formulation 2 (TF2) and the effect of food on the pharmacokinetics of BI…
- Trial name
- NCT05428436
- Testing
- Reference (R), Test treatment 1 (T1), Test treatment 2 (T2)
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Psychotic Disorders
Improving Heart and Metabolic Health in People With Severe Mental Illness Through a Long-term Clinical Trial
Background Cardiometabolic conditions-including cardiovascular disease, type 2 diabetes, and obesity-are highly prevalent among individuals with psychotic disorders.
- Trial name
- LAGOM (NCT06781801)
- Testing
- Intervention
- Where
- 6 sites in Sweden
- Volunteers
- 650 people
- Sponsor
- Vastra Gotaland Region
Individuality
Genetic & Environmental Determinants Of Immune Phenotype Variance: Establishing A Path Towards Personalized Medicine
The purpose of this study is to assess the determinants of immunologic variance within the general healthy population.
- Trial name
- LabExMI (NCT01699893)
- Testing
- unique arm
- Where
- France
- Volunteers
- 1,012 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Obesity
Individual Differences in Children's Susceptibility to Overeating
The portion size of foods has been identified as an important determinant of energy intake in children. It remains to be determined to what extent child weight status and the relative reinforcing value of food may interact with…
- Trial name
- NCT01905293
- Testing
- Feeding Study
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Gender Dysphoria
Evaluation of the Variation in Quality of Life During Medical Transition for Transgender People.
Transgender people can benefit from psychological, psychiatric, endocrinological support, sexual reassignment surgery, sexology support and dermatological care. The value of transitional care courses is scientifically recognized.
- Trial name
- TRANS'ITION (NCT05273112)
- Where
- 13 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Lille
Oral Health Knowledge, Oral Health Behavior Change
Improving Oral Health Knowledge and Habits in People With Diabetes Through a Theory Guided WhatsApp Education Program
The goal of this Educational interventional study is to test the usefulness of an educational program delivered through WhatsApp videos in increasing oral health knowledge and habits in people with Diabetes between the age of 18…
- Conditions
- Oral Health Knowledge, Oral Health Behavior Change, Diabetes Type 2
- Trial name
- NCT07323771
- Testing
- Health Belief Model (HBM) Based WhatsApp Oral Health Education Program, Educational Brochure Group
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Dow University of Health Sciences
Cancer, COVID
SafeFit Trial: Virtual Clinics to Deliver Universal Interventions in People With Cancer
Trial Phase: Phase III: Interventional Trial: Virtual clinics to deliver universal interventions to maintain and improve physical health, nutritional state and psychological wellbeing in people with cancer who are following…
- Trial name
- NCT04425616
- Testing
- Exercise, Psychological and Behaviour Change Support, Nutrition
- Where
- United Kingdom
- Volunteers
- 1,100 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Non-Communicable Chronic Diseases
Establishing a Physical Activity Referral Scheme for People With Noncommunicable Diseases in the German Healthcare System
The BewegtVersorgt project involved co-producing a physical activity referral scheme (PARS) for inactive persons with underlying non-communicable diseases.
- Trial name
- BewegtVersorgt (NCT04947787)
- Testing
- Physical activity referral scheme (PARS), Physical activity advice (PAA)
- Where
- Germany
- Volunteers
- 168 people
- Sponsor
- University of Erlangen-Nürnberg
Atrophy of Vocal Cord, Presbyphonia
PhoRTE® Therapy Efficacy: In-Person Versus Telehealth
This study compares how well voice therapy works when delivered in-person versus through telehealth for older adults with age-related voice problems.
- Conditions
- Atrophy of Vocal Cord, Presbyphonia, Dysphonia, Glottic Insufficiency
- Trial name
- NCT06934265
- Testing
- exuberant voice therapy
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Accidental Falls
The Effectiveness of a Self-managed Digital Exercise Programme to Prevent Falls in Older Community-dwelling People
The overall aim of the study is to evaluate the effectiveness of a digital self-management exercise program in preventing falls in community dwelling older people.
- Trial name
- SafeStepRCT (NCT03963570)
- Testing
- Safe Step - digital exercise program, Control group
- Where
- Sweden
- Volunteers
- 1,628 people
- Sponsor
- Umeå University
Parkinson Disease
Study in Parkinson's Disease of Exercise
The purpose of this study is to learn more about the effects of exercise on patients who have been recently diagnosed with Parkinson's disease (PD).
- Trial name
- SPARX (NCT01506479)
- Testing
- Moderate Exercise, Vigorous Exercise, No Intervention
- Where
- 3 sites in United States
- Volunteers
- 128 people
- Sponsor
- University of Colorado, Denver
Older People, Sports
Boxing, Taekwondo and Elastic Band Training on Body Composition and Physical Performance in Older Women
The objective of this clinical trial is to compare the effect of three physical interventions (Taekwondo, Boxing, and Elastic Band Training) on body composition and physical performance in older Chilean women.
- Conditions
- Older People, Sports, Martial Arts
- Trial name
- RCT (NCT06780020)
- Testing
- Effects of different interventions using boxing, Effects of different interventions using taekwondo, Effects of different interventions using Elastic Band
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Maule
Overweight and Obesity
A Theory-based Digital Intervention to Promote Weight Loss and Weight Loss Maintenance
Obesity can severely reduce quality and longevity of life and there is an urgent need to help people lose weight and maintain weight loss long term.
- Trial name
- NCT04291482
- Testing
- Choosing Health Intervention, Choosing Health Control
- Where
- Poland
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
COVID-19
A Study to Understand How the Use of Paxlovid Affected Healthcare Use in People With Pre-existing Conditions.
This is a cohort study that will include Paxlovid (nirmatrelvir-ritonavir) treatment eligible for people with a positive SARS-CoV-2 diagnostic test and at least one COVID-19 symptom.
- Trial name
- NCT07090486
- Testing
- nirmatrelvir-ritonavir
- Where
- United States
- Volunteers
- 14,000 people
- Sponsor
- Pfizer
Diabetes Mellitus, Type 2
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
The study is testing UBT251 in participants with type 2 diabetes. The purpose of this clinical study is to find out if UBT251 is effective and safe for treating participants with type 2 diabetes.
- Trial name
- NCT07668388
- Testing
- UBT251, Semaglutide
- Where
- 70 sites in United States, Australia and 7 more
- Volunteers
- 300 people
- Sponsor
- Novo Nordisk A/S
Healthy
A Study in Healthy People to Compare 2 Different Formulations of Nerandomilast Tablets When Taken With or Without Food
The main objective of this trial is to investigate two different formulations of nerandomilast and the effect of food on the pharmacokinetics of the new formulation following oral administration.
- Trial name
- NCT06624072
- Testing
- Nerandomilast 18 mg - adult formulation, Nerandomilast 1 mg - paediatric formulation
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy, Obesity
A Study in People With Overweight or Obesity to Test How Well Different Doses of BI 1820237 Are Tolerated When Given Alone or in Combination With Either Semaglutide or BI 456906
This study is open to adults between 18 and 55 years of age who are living with overweight or obesity. People with a body mass index (BMI) from 27 to 40 kg/m2 can join the study.
- Trial name
- NCT05751226
- Testing
- BI 1820237, semaglutide, BI 456906
- Where
- Germany
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim