Clinical trials: Differentiation
Autism Spectrum Disorder (ASD
Exploring the Physiological Mechanisms of Austism Through Organoids
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder affecting approximately 1% of the population, characterized by difficulties with social interaction and communication.
- Trial name
- EXPECT HYPE (NCT07494331)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Regenerative Medicine, Induced Pluripotent Stem Cells (iPSC) Production
SAFE-iPS - France's First Hospital-based Platform for the Production of Induced Pluripotent Stem Cells for the Regenerative Medicine of the Future
The objective of the study is to establish the first French hospital-based Good Manufacturing Practice (GMP)-compliant platform for the production of clinical-grade induced pluripotent stem cells (iPSCs) for future regenerative…
- Trial name
- SAFE-iPS (NCT07735559)
- Testing
- Blood Collection for iPSC Generation
- Where
- France
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Breast Cancer, Colorectal Cancer
Family Quality of Life Among Families With a Member Who is a Cancer Patient
RATIONALE: Developing a questionnaire that can be used to assess the quality of life among people who have a family member with cancer may help the study of cancer in the future.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00544336
- Testing
- questionnaire administration, survey administration, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Pregnancy Complication
Influence of Preconceptional Obesity on the Myometrial Cells Differentiation Toward a Contractyl Phenotype
The purpose of this study is to improve the understanding of cellular mecanism involved in delivery disorders in obese women, first by characterizing the hyperplasia phenomenon of myometrail cells induced by inflammatory…
- Trial name
- ObeDi (NCT01762683)
- Testing
- Myometrium biopsy and blood samples
- Where
- 2 sites in France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Sunscreen
A Study to Evaluate Usage of Mineral Sunscreens With Differentiated Whitening Attributes in Multi-Cultural Skin Tones
The purpose of the study is to evaluate the whitening potential of different mineral and chemical sunscreens across multi-cultural skin tones through instrumentation, imaging, and self-assessment.
- Trial name
- NCT06734299
- Testing
- Sunscreen A, Sunscreen B, Sunscreen C
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Hypertrophic Cardiomyopathy, Hypertensive Heart Disease
Differentiation HHD From HCM (EARLY-MYO-HHD)
Differentiating hypertrophic cardiomyopathy (HCM) from hypertensive heart disease (HHD) unavoidably encounters diagnostic challenges especially in patient of suspected HCM with history of hypertension.
- Trial name
- NCT03271385
- Testing
- evaluated by the predetermined differentiating formula
- Where
- China
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Chronic Periodontitis
Efficacy of Locally Delivred 1.2% Rosuvastatin Gel in Chronic Periodontitis
BACKGROUND: Chronic periodontitis (CP) is an inflammatory condition affecting tooth supporting tissues and alveolar bone that surround the tooth leading to formation of deepend gingival sulcus that is highly prone to pathologic…
- Trial name
- NCT02283515
- Testing
- Rosuvastatin
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Nephropathy
Identification of Corticomedullary Differentiation Along Different Stage of Pregnancy
Corticomedullary differentiation (CMD) abnormality (absent/reversed) is a parameter that can indicate possible nephropathy. The evolution of CMD across gestation had not been well established.
- Trial name
- NCT02193516
- Where
- Israel
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Infertility, IVF
Quality of Human Embryos in IVF, Culturing in Differentiated Oxygen
The goal of this clinical trial is to evaluate the importance of differential O2 tension to the developing embryos. As a secondary aim, we investigate the levels of reactive oxygen species (ROS) in spent media from the developing…
- Conditions
- Infertility, IVF, Embryo
- Trial name
- NCT05737381
- Testing
- Differential oxygen tension
- Where
- Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Diabetes Mellitus, Sport Injury
Cryopreserved Hair Follicles for Disease and Cell Replacement
To explore the application of cells expanded from plucked hair follicles after collection, transport, and cryopreservation, in disease modeling and cell-based therapies.
- Conditions
- Diabetes Mellitus, Sport Injury, Injury Traumatic
- Trial name
- NCT06764719
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acorn Biolabs Inc.
Type 2 Diabetes, Inflammation
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids
Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease.
- Conditions
- Type 2 Diabetes, Inflammation, Insulin Sensitivity/Resistance, Fatty Acids, Omega-3
- Trial name
- NCT04485871
- Testing
- Omega-3 fatty acids
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institut de Recherches Cliniques de Montreal
Dental Pulp Regeneration, Dental Pulp Diseases
Development of a Model to Evaluate Regenerative Endodontic Techniques Using Extract Human Teeth
Millions of teeth are saved each year by root canal therapy. Although current treatment modalities offer high levels of success for many conditions, an ideal form of therapy might consist of regenerative approaches in which…
- Trial name
- NCT00595595
- Where
- United States
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Healthy
Effect of Cyclic Tensional Force on Osteogenic Differentiation of Human Periodontal Ligament Stem Cells
The purpose of this study is to observe cyclic tensional force on the osteogenic differentiation of human periodontal ligament stem cells.
- Trial name
- NCT00172744
- Where
- 2 sites in Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke, Visual Defects
Differentiation of Human Body Balance Disorders
Our research aims to analyze the possibilities of functional assessment of imbalances in the human body. Using the available, commonly known and used tests and devices for objective examination of static and dynamic body balance…
- Conditions
- Stroke, Visual Defects, Labyrinth Diseases, Cervical Spine Degenerative Disease
- Trial name
- NCT07395180
- Testing
- Patients after stroke, Patients with posterior columns of the spinal cord, Patients with labyrinth diseases
- Where
- Poland
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
COPD, Emphysema
Leukocyte Function in Chronic Obstructive Pulmonary Disease (COPD)
The aim of this study is to investigate the mechanisms whereby leukocytes are recruited to the lung in chronic obstructive pulmonary disease (COPD) and cause tissue destruction.
- Conditions
- COPD, Emphysema, Chronic Bronchitis
- Trial name
- NCT00147082
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Type 2 Diabetes
Effect of NF-кB Dependent Proinflammation on Osteogenic Differentiation of the Mesenchymal Stem Cells in Type 2 Diabetes
This study determines whether NF-кB dependent proinflammatory state found in type 2 diabetes yield to a higher RAGE activation in the mesenchymal stem cell, as well as the effects of the proinflammation on osteoblast…
- Trial name
- NCT02286128
- Where
- Thailand
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Coronary Heart Disease
Innovation Research of Differentiation and Treatment Methods Based on CHD Phlegm and Blood Stasis Syndrome
Coronary heart disease is still the major cause of death in China. Chinese medicine plays more and more important role in CHD prevention and treatment. Phlegm and blood stasis are its major pathological basis.
- Trial name
- NCT02967718
- Where
- China
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Jingqing Hu
Intestinal Tuberculosis, Pulmonary Tuberculosis
Intestinal Tuberculosis Diagnostics and the Differentiation From Crohn's Disease
One aims to devise a method for the screening and differentiation of intestinal tuberculosis and Crohn's Disease. Additionally, one aims to detect and survey multidrug resistant TB.
- Conditions
- Intestinal Tuberculosis, Pulmonary Tuberculosis, Crohn's Disease
- Trial name
- NCT01503099
- Where
- 2 sites in India, Norway
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Lovisenberg Diakonale Hospital
Chronic Respiratory Failure
Treatment of CRF With Syndrome Differentiation of TCM
Taking the patients with chronic respiratory failure caused by COPD as the research object and the acute exacerbation of COPD as the main outcome index, the investigators hope to establish the syndrome differentiation and…
- Trial name
- NCT04694755
- Testing
- Traditional Chinese medicine prescription
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Henan University of Traditional Chinese Medicine
Yin Deficiency Syndrome
Standard Scale for Syndrome Differentiation of Yin Deficiency Syndrome
An version of the standard scale for syndrome differentiation of Yin Deficiency Syndrome is not available yet for Chinese medicine.
- Trial name
- SFYDS (NCT04806490)
- Testing
- the diagnosis for Yin Deficiency Syndrome
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital