Clinical trials: Differentiation
Stroke, Visual Defects
Differentiation of Human Body Balance Disorders
Our research aims to analyze the possibilities of functional assessment of imbalances in the human body. Using the available, commonly known and used tests and devices for objective examination of static and dynamic body balance…
- Conditions
- Stroke, Visual Defects, Labyrinth Diseases, Cervical Spine Degenerative Disease
- Trial name
- NCT07395180
- Testing
- Patients after stroke, Patients with posterior columns of the spinal cord, Patients with labyrinth diseases
- Where
- Poland
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Differenciation of Stromal-vascular Fraction Cells
A Study Using Human Abdominal Adipose Tissue Biopsies to Characterize the Role of Endocannabinoids in Adipocyte Differentiation
Abdominal obesity and type 2 diabetes are associated with hyperactivation of the endocannabinoid system. Several animal and human studies indicate that circulating endocannabinoid levels correlate with body fat mass.
- Trial name
- ECTADIF (NCT07567287)
- Testing
- Collection of adipose tissue samples
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Myoclonus, Evoked Potential
Electrophysiological Characteristics and Anatomical Differentiation of Epileptic and Non-epileptic Myoclonus.
This study was conducted on a series of patients with myoclonus to identify the electrophysiological characteristics and the anatomical classification of myoclonus of different causes.
- Trial name
- NCT04235452
- Testing
- Somatosensory evoked potential
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Adipocyte Differentiation, Insulin Resistance
Impaired Adipogenesis in Insulin Resistance: Pilot Clinical and In Vitro Studies
Obesity is a strong risk factor for developing type 2 diabetes (T2DM), but the reasons for this are not fully understood. In particular, it is not known why some obese people develop T2DM while other obese individuals do not.
- Trial name
- NCT00560469
- Testing
- Administration of 70% deuterated water
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Periodontal Diseases
Impact of Periodontal Treatment on Growth Differentiation Factor-15 Levels
In light of the controversy that are already approved but that however still exists regarding the efficacy and influence the management of Periodontitis, the aim of this study was to evaluates, at 6-months follow-up, the…
- Trial name
- NCT05720481
- Testing
- Full mouth Scaling and root planing, Quadrant Scaling and root planing
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Catania
Type 2 Diabetes, Inflammation
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids
Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease.
- Conditions
- Type 2 Diabetes, Inflammation, Insulin Sensitivity/Resistance, Fatty Acids, Omega-3
- Trial name
- NCT04485871
- Testing
- Omega-3 fatty acids
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institut de Recherches Cliniques de Montreal
Localization-Related (Focal) (Partial) Idiopathic Epilepsy and Epileptic Syndromes With Seizures of Localized Onset, TRAIL: Tumor Necrosis Factor Related Apoptosis Inducing Ligand MCP-2
Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure
1. Evaluation of the role of TRAIL and MCP-2 in differentiation between epileptic seizure and psychogenic non-epileptic seizure. 2. Possible role to predict the prognosis of patients with epileptic seizure.
- Conditions
- Localization-Related (Focal) (Partial) Idiopathic Epilepsy and Epileptic Syndromes With Seizures of Localized Onset, TRAIL: Tumor Necrosis Factor Related Apoptosis Inducing Ligand MCP-2, MCP-2: Monocyte Chemo-attractant Protein-2
- Trial name
- seizure (NCT05571371)
- Testing
- Measuring inflammatory serum biomarkers
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Esraa Mostafa Ahmed Abdel Aal
Benign Skin Tumor, Basal Cell Carcinoma
Study to Examine Lesions of the Skin Using Confocal Laser Microscopy
Using ex-vivo confocal laser scanning microscopy, a reliable statement can be made about the extent, histological structure and possible significance of a skin change without having to send tissue samples for demanding and…
- Conditions
- Benign Skin Tumor, Basal Cell Carcinoma, Melanoma, Squamous Cell Cancer
- Trial name
- NCT06598137
- Testing
- Ex vivo confocal laser microscopy
- Where
- Germany
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Hiv, Transmission Vertical
Differentiated Service Delivery for Pregnant and Postpartum Women Living With HIV and Their Infants
Differentiated service delivery (DSD) is an evidence-based HIV care and treatment model endorsed by the World Health Organization (WHO) that simplifies HIV services for clients who are clinically stable, improving the quality and…
- Conditions
- Hiv, Transmission Vertical, Viremia, Health Care Acceptability
- Trial name
- NCT06629753
- Testing
- Differentiated service delivery model
- Where
- Kenya
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gallbladder Cancer
Poorly Differentiated Adenocarcinoma With Signet Ring Cells of the Gallbladder Producing a High Level of Alpha-fetoprotein: a Case Report
Alpha-fetoprotein (AFP) can become elevated in hepatocellular carcinoma (HCC), yolk sac tumors and other malignant tumors of various organs.
- Trial name
- NCT05559229
- Testing
- laparoscopic whole-layer cholecystectomy
- Where
- Japan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- junya mita
Pregnancy Complication
Influence of Preconceptional Obesity on the Myometrial Cells Differentiation Toward a Contractyl Phenotype
The purpose of this study is to improve the understanding of cellular mecanism involved in delivery disorders in obese women, first by characterizing the hyperplasia phenomenon of myometrail cells induced by inflammatory…
- Trial name
- ObeDi (NCT01762683)
- Testing
- Myometrium biopsy and blood samples
- Where
- 2 sites in France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Healthy
Effect of Cyclic Tensional Force on Osteogenic Differentiation of Human Periodontal Ligament Stem Cells
The purpose of this study is to observe cyclic tensional force on the osteogenic differentiation of human periodontal ligament stem cells.
- Trial name
- NCT00172744
- Where
- 2 sites in Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sunscreen
A Study to Evaluate Usage of Mineral Sunscreens With Differentiated Whitening Attributes in Multi-Cultural Skin Tones
The purpose of the study is to evaluate the whitening potential of different mineral and chemical sunscreens across multi-cultural skin tones through instrumentation, imaging, and self-assessment.
- Trial name
- NCT06734299
- Testing
- Sunscreen A, Sunscreen B, Sunscreen C
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Premature Birth
Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants
The goal of this clinical study is to test a new, novel medical device designed to improve speech sound differentiation among hospitalized preterm infants.
- Trial name
- NCT06063122
- Testing
- smallTalk NICU Active
- Where
- 2 sites in United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Thrive Neuromedical, LLC
Erythroid Differentiation Regulator 1 (Erdr1) Cytokine
Expression of Erythroid Differentiation Regulator 1 (Erdr1) in Vitiligo
Expression of Erythroid differentiation regulator 1 (Erdr1) cytokine in vitiligo
- Trial name
- NCT03377998
- Testing
- skin biopsy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Overweight
The Influence of Acute Moderate-intensity Continuous Exercise on Appetite Regulation
A key area of obesity research has focused on the link between appetite, energy balance and weight control. Within this area, several appetite-related hormones and cellular cytokines have been identified as key signals…
- Trial name
- NCT06296511
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Atherosclerosis
Macrophage Polarization in Response to Macronutrient Intake in Healthy Humans: A Randomized Clinical Study
Macrophages can exhibit distinct phenotypes and functions in response to stimuli and can polarize into one of three distinct phenotypes: a pro-inflammatory (M1), an anti-inflammatory pro-tissue (M2) and metabolically-activated…
- Trial name
- NCT03173677
- Testing
- Lipid Intake, Glucose intake, Protein intake
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- King Saud Bin Abdulaziz University for Health Sciences
Fluid Retention Tissue, Perfusion; Complications
Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction
In the weightlessness of space and significant alterations of terrestrial 1 g (1 gravity equivalent) head-to-foot hydrostatic pressure gradients, astronauts experience a dramatic fluid redistribution of ~ 2 liters from the legs…
- Trial name
- NIID (NCT06405282)
- Testing
- Manual Lymphatic Drainage, Near infrared spectroscopy, Temperature
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Infertility, Male, Gene Abnormality
Spermatogonial Differentiation Via Testicular Organoid
Purpose: This clinical trial aims to explore the potential for human sperm production in vitro by sustaining a laboratory-cultured adult testicular environment.
- Conditions
- Infertility, Male, Gene Abnormality, Sterility, Male
- Trial name
- SDTO (NCT06841861)
- Testing
- Stem cell, Genetic Screening, Genetic Reprogramming
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- CellARTs Inc.
Ischemic Stroke
Curative Efficacy of Secondary Prevention for Patients With Ischemic Stroke Through Syndrome Differentiation of TCM
The purpose of this study is to assess the efficacy and safety of Naoxintong Capsule in the secondary prevention of ischemic stroke by the multi-center, randomized,double-blind，placebo-controlled trial design project.
- Trial name
- NCT02334969
- Testing
- Naoxintong Capsule
- Where
- 24 sites in China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Xiaofei Yu