Clinical trials: Diffuse Parenchymal Lung Disease
Diffuse Parenchymal Lung Diseases
Validation of Alveolar Probe-based Confocal Laser Endomicroscopy Descriptors in Diffuse Parenchymal Lung Diseases
Diffuse parenchymal lung diseases (DPLD) include a variety of respiratory conditions that affect either the pulmonary interstitium or the alveolar space .
- Trial name
- Microsemio-PI (NCT02961335)
- Testing
- Bronchoscopy, Confocal microendoscopy, Biopsy sampling
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Rouen
Interstitial Lung Disease, Diffuse Parenchymal Lung Disease
Hydroxychloroquine (HCQ) in Pediatric Interstitial Lung Disease (ILD)
This is an exploratory Phase 2, randomized, double-blind, placebo-controlled, parallel-group, multinational study investigating the initiation or withdrawal of hydroxychloroquine in subjects with chILD.
- Conditions
- Interstitial Lung Disease, Diffuse Parenchymal Lung Disease, Children´s Interstitial Lung Disease
- Trial name
- HCQ-chILD-EU (NCT02615938)
- Testing
- Hydroxychloroquine sulfate
- Where
- 9 sites in Germany
- Volunteers
- 35 people
- Sponsor
- Matthias Griese
Diffuse Parenchymal Lung Diseases
Prospective Data Collection of Patients With Diffuse Parenchymal Lung Diseases
The purpose of this study is to generate a prospective database of all patients evaluated for diffuse parenchymal lung diseases to provide much needed data on the various disease aetiologies, incidence and prevalence rates…
- Trial name
- NCT01600378
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore General Hospital
Idiopathic Pulmonary Fibrosis, Idiopathic Interstitial Pneumonia
Clinical Course of Interstitial Lung Diseases: European IPF Registry and Biobank
Born out of the European Union 7th Framework Programme funded project European IPF Network (eurIPFnet), the European IPF Registry (eurIPFreg) has become Europe's leading database of longitudinal data from IPF patients, including…
- Conditions
- Idiopathic Pulmonary Fibrosis, Idiopathic Interstitial Pneumonia, Interstitial Lung Diseases, Diffuse Parenchymal Lung Diseases
- Trial name
- eurIPFreg (NCT02951416)
- Testing
- patient registry (observation and biomaterial sampling)
- Where
- 7 sites in Austria, France and 3 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Andreas Guenther
Diffuse Parenchymal Lung Disease, Frailty
Evaluation of Patients With Diffuse Parenchymal Lung Diseases Regarding Frailty
There are very few studies in the literature examining the frailty levels of diffuse parenchymal lung disease (DPLD) patients and its effect on their functional status despite the high prevalance of frailty in patients with DPLD…
- Conditions
- Diffuse Parenchymal Lung Disease, Frailty, Physical Inactivity
- Trial name
- NCT06171425
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Diffuse Parenchymal Lung Disease
Ultra-Low Dose Computed Tomography For Diagnosis And Follow-Up Of Patients With Diffuse Parenchymal Lung Disease (DPLD)
The primary intention of this study is to determine the diagnostic performance of ultra-low-dose CT (ULDCT) in diagnosis and follow-up of diffuse parenchymal lung disease (DPLD).
- Trial name
- NCT04392726
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Idiopathic Pulmonary Fibrosis, Diffuse Parenchymal Lung Disease
Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic pulmonary fibrosis (IPF) is an illness characterized by progressive decline in lung function and premature death from respiratory failure.
- Conditions
- Idiopathic Pulmonary Fibrosis, Diffuse Parenchymal Lung Disease, Interstitial Lung Disease
- Trial name
- NCT01462006
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Virginia
Diffuse Parenchymal Lung Diseases
The Diagnostic Yield and Safety of Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Diseases
The Diagnostic yield and Safety of transbronchial cryobiopsy in the diagnosis of diffuse parenchymal lung diseases are investigated in this multicenter, prospective and real world study.
- Trial name
- NCT03704233
- Testing
- Transbronchial cryobiopsy
- Where
- 26 sites in China
- Volunteers
- 350 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Diffuse Parenchymal Lung Diseases
Fibered Confocal Fluorescence Microscopy Imaging in Patients With Diffuse Parenchymal Lung Diseases
Fibered confocal fluorescence microscopy (FCFM) (CellvizioR Lung, MaunaKea Technologies, France) could potentially provide diagnostic information on fibrosis and inflammation of the distal air spaces associated with diffuse…
- Trial name
- NCT01624753
- Testing
- confocal microscopy
- Where
- Singapore
- Volunteers
- 27 people
- Sponsor
- Singapore General Hospital
Diffuse Parenchymal Lung Disease
The Clinical Value of Serum KL-6 Changes on Evaluating Disease Development in Different Diffuse Parenchymal Lung Disease
Diffuse Parenchymal Lung Disease(DPLD) is a chronic progressive fibrosis lung disease that with a highly variable clinical process.Krebs von den Lungen-6 (KL-6) is a high-molecular-weight glycoprotein, classified as human MUC1…
- Trial name
- NCT03101397
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease
Race, Ethnicity, and Diffuse Parenchymal Lung Disease
The purpose of this study is to identify factors that contribute to higher mortality rates among blacks and Hispanics with diffuse parenchymal lung disease.
- Conditions
- Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease, Diffuse Parenchymal Lung Disease
- Trial name
- NCT00453713
- Where
- United States
- Volunteers
- 565 people
- Sponsor
- Columbia University
Diffuse Parenchymal Lung Disease, Pulmonary Hypertension
Effect of Sildenafil on Diffusion Capacity in Patients With PH and Parenchymal Lung Disease
The purpose of this study was to investigate the acute effects of sildenafil on diffusion capacity, a commonly performed pulmonary function test, which is used to assess the lungs' gas exchange capability.
- Trial name
- NCT01948518
- Testing
- Oral sildenafil 20 mg
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Cleveland Clinic