Clinical trials: Diffusion-weighted MRI
Endovascular Thrombectomy
Medical Imaging Screening for Posterior-circulation Ischemic Stroke
Patients with ischemic stroke in the posterior circulation continue to have high rates of mortality and disability, even with aggressive treatment.
- Trial name
- NCT06094569
- Testing
- Endovascular Therapy
- Where
- 4 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Tianjin Huanhu Hospital
Healthy Volunteers
Optimal Low B-value in Intravoxel Incoherent Motion Diffusion-weighted MR Imaging of the Brain
Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.
- Trial name
- NCT02411864
- Testing
- different low b-values distribution
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Carcinoma, Hepatocellular
3T MRI to Predict TACE Response of HCC
This study is a prospective clinical study using DCE-MRI, DWI and MRS in 3T scanner to evaluate tumors in patients with unresectable HCC after TACE. A total of 100 subjects will be recruited.
- Trial name
- NCT02070822
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Prostatic Neoplasms, Prostate Cancer
Rectal Gas Removal Through Small Catheter Placement Prior to MRI of the Prostate
The presence of rectal gas can cause distortion at air-tissue interfaces on diffusion-weighted images (DWI) of prostate MRI and reduce image quality due to these susceptibility artifacts.
- Trial name
- GAS (NCT03987737)
- Testing
- small urinary catheter placement in the rectum
- Volunteers
- 46 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Cancer
Screening Contralateral Breast Cancers in Patients With Newly Diagnosed Breast Cancer
In women with newly diagnosed breast cancer, synchronous contralateral breast cancer is reported in 1% to 3%. During the initial diagnosis of breast cancer, it is important to detect the contralateral cancer to avoid second round…
- Trial name
- NCT05307757
- Where
- South Korea
- Volunteers
- 1,098 people
- Sponsor
- Seoul National University Hospital
Focal Epilepsy
Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery
This project will test the accuracy of a novel diffusion-weighted magnetic resonance imaging (DWMRI) approach using a deep convolutional neural network (DCNN) to predict an optimal resection margin for pediatric epilepsy surgery…
- Trial name
- NCT04986683
- Testing
- Brain magnetic resonance imaging, Neuro-psychology testing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation
Screening of Endovascular Thrombectomy With MRI in Acute Ischemic Stroke
The goal of this observational study is to learn about the role of MRI evaluation based on FVH-DWI mismatch principle in preoperative evaluation of endovascular thrombolectomy.
- Conditions
- Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation, Endovascular Thrombectomy
- Trial name
- NCT06213870
- Testing
- Surgical criteria
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Tianjin Huanhu Hospital
Prostate Cancer, Bladder Cancer
USPIO-enhanced and Diffusion-weighted MRI for the Detection of Pelvic Lymph Node Metastases
Preoperative detection of lymph node metastases in patients with prostate or bladder cancer is crucial for selection of the appropriate treatment strategy (surgery, androgen deprivation with/or without radiation therapy or…
- Trial name
- NCT00622973
- Testing
- Imaging: diffusion-weighted MRI, Sinerem (USPIO) enhanced MRI
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Rett Syndrome
The Findings of MR Imaging in Rett Syndrome
Introduction: Rett Syndrome is a neurodevelopmental disease that primarily affects girls. Clinically, patients are normal before six months to one and half years old, and then develop progressive severe problems with…
- Trial name
- NCT02903056
- Testing
- Rett Syndrome
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Adnexal Tumor
Diffusion MRI (Magnetic Resonance Imaging) Using ADC (Apparent Diffusion Coefficient) Histograms in the Evaluation of Adnexal Tumor Aggressiveness
Diffusion-weighted sequences have been routinely performed for years to study the pelvis. They have been so far mainly qualitatively interpreted, that is to say as the absence or presence of an hypersignal at a high b value.
- Trial name
- NCT02742870
- Testing
- Correlation of MRI results with clinical characteristics of the adnexal mass
- Where
- Belgium
- Volunteers
- 126 people
- Sponsor
- Brugmann University Hospital
Atrial Fibrillation
Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings
The purpose of this prospective randomized controlled study is to evaluate the risk of asymptomatic cerebral embolism during catheter ablation of atrial fibrillation (AF) with AI-HPSD strategy versus standard radiofrequency…
- Trial name
- NCT04408716
- Testing
- Ablation Index Guided High-Power Short-Duration Strategy, Standard Radiofrequency Ablation Technique
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Aging, Music
Brain Imaging and Behavioural Changes Following Cued-movement Training of Finger Sequences in Healthy Older Adults
The goal of this study is to examine changes in the brain, behavior, and personal experience when music is used to guide learning of finger movement sequences (compared to visual stimuli alone) in healthy older adults.
- Conditions
- Aging, Music, Motor Activity, Magnetic Resonance Imaging
- Trial name
- NMSOA (NCT06174740)
- Testing
- Music-cued audiovisual motor training, Visually-cued motor training
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Peritoneal Carcinomatosis, Peritoneal Metastases
Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal Neoplasms
Diffusion-weighted magnetic resonance imaging (DWI/MRI) has been described in recent literature as a highly sensitive and specific modality for the detection of peritoneal metastases PM.
- Conditions
- Peritoneal Carcinomatosis, Peritoneal Metastases, Appendix Cancer, Appendix Neoplasm
- Trial name
- DWI-HighRisk (NCT05623787)
- Testing
- Whole-body diffusion-weighted magnetic resonance imaging
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Glioma
The Predictive Value of MRI for Adult-type Diffuse Gliomas
The goal of this observational study is to learn about the diagnostic value of preoperative MRI examination for adult-type diffuse gliomas.
- Trial name
- MRI; glioma; (NCT06572592)
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Prostate Cancer
CombIning advaNces in imagiNg With biOmarkers for improVed Diagnosis of Aggressive prosTate cancEr
To enable the paradigm of mp-MRI before biopsy in all patients with suspected prostate cancer by better selecting patients who will benefit from diagnostic MRI and by improving the performance of the mp-MRI itself
- Trial name
- INNOVATE (NCT02689271)
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 365 people
- Sponsor
- University College, London
Breast Cancer
Diffusion Weighted MRI for Lymphnodes in the Axilla
This study is going to compare diffusionweigthed MRI scanning to the result of surgey in patients with metastasis from brestcancer in the axilla
- Trial name
- NCT00276211
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital at Herlev
Leukaemia
PUMA (Paediatric Osseous Marrow Assessment)
This is a pilot cancer imaging study investigating change in the apparent diffusion coefficient (ADC) at a single time point post-transplantation in patients.
- Trial name
- PUMA (NCT03466944)
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Esophageal Tumor
PET-CT vs DWI-MRI in Response Evaluation in Esophageal Cancer
In patients with esophageal cancer (EC) neo-adjuvant chemoradiation (nCRT) followed by surgery with curative intent leads to objective responses in 45 to 60%, whereas 20-35% of the patients had no residual tumor (ypT0N0) at…
- Trial name
- PET/MRI-EC (NCT02839109)
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- University Medical Center Groningen
Acute Ischemic Stroke, Stroke
MRI-SWI as a Predictor of Functional Outcome in Acute Ischemic Stroke
The purpose of the study is to use diffusion tensor imaging (DTI) derived axial diffusivity and susceptibility weighted imaging (SWI) to evaluate the severity of acute ischemic stroke and to predict its functional outcome.
- Conditions
- Acute Ischemic Stroke, Stroke, Cerebral Stroke, Cerebrovascular Accident
- Trial name
- NCT00696306
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University WanFang Hospital
Prostate Cancer
Role of PET/CT With Fluorine-18 Tracers of Bone Metastases in Prostate Cancer
Compare PET/CT and MRI for the early detection of bone metastases of prostate cancer: diagnostic performance and impact on the patient management.Determine the lowest cost strategy according to the precise clinical circumstances.
- Trial name
- FLUPROSTIC (NCT01501630)
- Testing
- performance of PET/CT and whole-body MRI
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris