Clinical trials: Digestive Health
Crohn Disease
Mother-to-Infant Transfer of Bacteriome, Fungome, Virome, and Metabolome in Health and Crohn's Disease
Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are caused by the loss of mucosal tolerance towards the commensal microbiota resulting in inflammatory responses.
- Trial name
- NCT05112497
- Testing
- No intervention procedure
- Where
- Hong Kong
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mental Health Wellness 2, Health Behavior
Tracking Our Lives Study
College women are at risk for eating disorders, which have profound health impacts. Cross-sectional studies have shown that the use of dietary self-monitoring is associated with eating disorder risk among college students.
- Conditions
- Mental Health Wellness 2, Health Behavior, Eating Disorders
- Trial name
- NCT04052529
- Testing
- Dietary self-monitoring
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hepatitis A Vaccine
This Study Will Evaluate the Persistence of Hepatitis A Antibodies, 8 Years and 10 Years Later, in Children Who Had Received Havrix at Selected Health Centres of Panama
The purpose of this study is to evaluate the persistence of hepatitis A antibodies, approximately 8 years and 10 years post vaccination with the complete series of Havrix (2 doses) and the partial series completion (1 dose).
- Trial name
- NCT02712359
- Testing
- Blood sample collection
- Where
- 3 sites in Panama
- Volunteers
- 1,201 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dyslipidemia, Diabetes
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Fructose-containing sugars have been implicated in the epidemics of obesity, diabetes and related cardiometabolic disorders. This view is supported by lower quality evidence from ecological observations, animal models, and select…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT02716870
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dysentery, Diarrhoea
Solar Disinfection (SODIS) of Drinking Water for Use in Developing Countries or in Emergency Situations
SODISWATER was a health impact assessment study investigating the effect of sunlight to inactivate microbial pathogens in drinking water.
- Trial name
- SODISWATER (NCT01306383)
- Testing
- SODIS Bottle
- Where
- 3 sites in Cambodia, Kenya and 1 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Intestinal Disorder, Glucose Metabolism Disorders
Grain Fibre and Gut Health
Wholegrain fibre is known to affect on the gut health, but also may cause intestinal discomfort. Thus, many individuals may avoid the consumption of whole grain cereals in spite of their known health benefits, and may in this…
- Conditions
- Intestinal Disorder, Glucose Metabolism Disorders, Inflammation
- Trial name
- FIBREFECTS (NCT03550365)
- Testing
- Rye bran bread intervention, Rye bread intervention, Wheat bread diet
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Hepatitis b Vaccine
Assessment of HBV Vaccine Immunity After 18 Years
The purpose of this study is to assess HBV immunity and institute policy regarding the Hepatitis B vaccination practices in the IDF among a cohort that was vaccinated during infancy.
- Trial name
- NCT01590381
- Where
- Israel
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Diarrhea
Health Impact Study of Aquatabs in Tamale, Ghana
The purpose of this study to determine whether Aquatabs, a water treatment tablet, reduces diarrheal diseases in a peri-urban population of Tamale, Ghana.
- Trial name
- NCT00252928
- Testing
- Sodium dichloroisocyanurate (NaDCC) tablets
- Where
- 3 sites in United States, Ghana
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Colorectal Cancer
The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
The investigators will expand an existing, patient-centered, health literacy strategy to promote longer-term adherence to colorectal cancer (CRC) screening in resource-limited, rural health clinics via colonoscopy or annual fecal…
- Trial name
- NCT04313114
- Testing
- health literacy appropriate education and demonstration, shared decision making, automated call reminders or automated texts
- Where
- 3 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Colorectal Cancer, Mortality
Dietary Patterns, Metabolomics and Colorectal Cancer Risk
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in American men and women with ≥130,000 new cases each year.
- Trial name
- NCT03364582
- Testing
- Observed dietary pattern
- Volunteers
- 173,230 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Mucositis
Surgical Protocol for Prevention of Mucositis
The main goal of implant therapy is to obtain long-term peri-implant health. Among local risk factors in the etiology of peri-implant diseases the absence of keratinized tissue (KT) around the implant has been reported.
- Trial name
- NCT04628520
- Testing
- Free gingival graft, Collagen matrix, Maintenance
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
GI Symptoms
A Pilot Study Evaluating the Impact of a Prebiotic Soda on Gastrointestinal Symptoms in Users of GLP-1 Agonists
The main objective of this study is to assess the impact of drinking a prebiotic soda on the gastrointestinal (GI) symptoms associated with the use of GLP-1 receptor agonists compared to usual fluid intake.
- Trial name
- NCT07744360
- Testing
- Prebiotic Soda
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Olipop, PBC
Breast Carcinoma, Cervical Carcinoma
CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers
This randomized research trial studies the Community-based Health Information Technology (HIT) Tools for Cancer Screening and Health Insurance Promotion (CATCH-UP) intervention in increasing cancer screening and prevention care…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma, Health Status Unknown
- Trial name
- NCT02355262
- Testing
- Informational Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Constipation, Diarrhea
Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population
The purpose of this study is to investigate the effect of a daily supplement consisting of the probiotic bacteria, Lactobacillus reuteri, on the digestive health among persons 65 years and older.
- Conditions
- Constipation, Diarrhea, Indigestion, Reflux
- Trial name
- NCT01837940
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Sweden
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Gastrointestinal Discomfort, Bloating
Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women
This study looks at whether a daily probiotic supplement can help improve mild-to-moderate stomach and digestive symptoms, such as gas and bloating, in women who also experience symptoms commonly associated with hormonal…
- Trial name
- NCT07831317
- Testing
- Active: Multi-strain probiotic dietary supplement
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Daily Nouri
Oral Bacteria, Halitosis
Effect of a Probiotic Water on Oral Health in Adults
The purpose of this study is to evaluate the effects of consuming a probiotic on salivary, plaque, and tongue bacteria, as well as oral malodor (bad breath).
- Trial name
- NCT04473404
- Testing
- Streptococcus salivarius DB-B5 - 2 billion CFU/day, Streptococcus salivarius DB-B5 - 10 billion CFU/day
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dose Biosystems Inc.
Human Papilloma Virus, Cervical Cancer
Integrating a Health Information Technology System for Primary and Secondary Cervical Cancer Prevention
The project aims to increase HPV vaccination and cervical cancer screening through a web-based mobile health education program called, Wheel of Wellness (WoW) and a brief negotiated interview (BNI).
- Conditions
- Human Papilloma Virus, Cervical Cancer, Human Papillomavirus Infection, Oropharyngeal Cancer
- Trial name
- NCT03346915
- Testing
- WoW and BNI
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Cancer of the Colon
Colorectal Cancer Screening in a Community Health Setting
This randomized controlled pilot study at the Health Annex, Family Practice \& Counseling Network (FPCN), a community clinic in Southwest Philadelphia, aimed at providing data on the feasibility of a mailed FIT approach to CRC…
- Trial name
- NCT03072095
- Testing
- Text-only, Text + Lottery
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Nausea, Pain
Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days
Randomized trial which will aim to evaluate whether prophylactic use of ondansetron and ibuprofen will decrease side effects associated with medical abortion and increase patient satisfaction.
- Trial name
- NCT05819619
- Testing
- Prophylactic use of ibuprofen and ondansetron post misoprostol administration, Use of ibuprofen and ondansetron at symptom onset post misoprostol administration
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health