Clinical trials: Digestive Health, active
Practice Guidelines for Primary Care of Acute Abdomen
Effectiveness of Implementing the Adapted Practice Guidelines for Primary Care of Acute Abdomen in Zambia: An Effectiveness-Implementation Hybrid Type 2 Study Design.
The study aims 1) to adapt, 2) to develop implementation strategies for and 3) to evaluate the effect of implementing a practice guideline for acute abdomen at primary care level in Zambia.
- Trial name
- NCT07587190
- Testing
- Practice guidelines for primary care of acute abdomen, No intervention
- Where
- Zambia
- Volunteers
- 280 people
- Sponsor
- University of Bergen
Colorectal Cancer, Colorectal Neoplasms
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
- Trial name
- NCT07896174
- Testing
- Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
- Where
- Hungary
- Volunteers
- 480 people
- Sponsor
- Semmelweis University
Eating Disorders
Eating Disorder Chatbot Optimization
The purpose of this study is to optimize an automated digital chatbot intervention for adults with clinical or subclinical eating disorders.
- Trial name
- NCT07218302
- Testing
- Digital Chatbot Program
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Washington University School of Medicine
HIV Infection, HBV Infection
"Pregnancy and Viral Infections: Impact on Pregnant Women and Their Children. French Prospective Cohort"
The VIROPREG study is a French prospective multicenter cohort study that aims to assess the impact of viral infections and antiviral treatments received during pregnancy on maternal and child health.
- Conditions
- HIV Infection, HBV Infection, HDV Infection, HCV Infection
- Trial name
- VIROPREG (NCT07412977)
- Testing
- Blood sampling, Umbilical cord blood sampling, Survey using a questionnaire
- Where
- France
- Volunteers
- 5,160 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Colorectal Cancer
CPHARM - CRC Study
Colorectal cancer is one of the most common cancers in Malaysia and worldwide. Although it can often be prevented or treated successfully when detected early, many people in Malaysia are diagnosed at an advanced stage.
- Trial name
- NCT07714291
- Testing
- Health awareness campaign
- Where
- Malaysia
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Monash University Malaysia
Depression - Major Depressive Disorder, Anxiety
Impact of Behavioral Activation on Depression and Quality of Life in Patients with Colon Cancer
The purpose of this randomized clinical trial is to study anxiety and depression symptoms at diagnosis in patients with colon cancer. Previous studies have shown that so-called.
- Conditions
- Depression - Major Depressive Disorder, Anxiety, Colon Cancer
- Trial name
- BAdepCa (NCT06745700)
- Testing
- Brief Behavioural Activation, Care as usual
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Region Västmanland
Colo-rectal Cancer, Colon Lesion
Compare the Patient Satisfaction and Effectiveness After Novel Application-based or Conventional Health Education of Bowel Preparation for Colonoscopy
Colorectal cancer is the cancer with highest incidence in Taiwan. The disease itself and subsequent treatment cause huge impact on the physical, psychological, and spiritual parts and social role of a patient.
- Trial name
- NCT06560671
- Testing
- novel type of health education
- Where
- Taiwan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Neoplasms, Breast Neoplasms
Increasing Breast and Colorectal Cancer Screening in the Community
The goal of the proposed study is to conduct a pilot randomized controlled trial (RCT) of Chi gung, a community-based intervention using peer education and tailored navigation to simultaneously improve colorectal (CRC) and breast…
- Trial name
- NCT07748377
- Testing
- Chi gung: Stay Well, Live Well
- Where
- 7 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gastrointestinal Discomfort, Digestive Well Being
Evaluation of Gut-Related Well-Being and Mood Effects of a Daily Nutritional Food Ingredient From the Co-Fermentation of Fungal Mycelium (Pleurotus Pulmonarius) and Microalgae (Chlorella Vulgaris)
The purpose of the study is to evaluate the gut-related well-being and mood effects of a food ingredient obtained from the co-fermentation of oyster mushroom mycelium (Pleurotus pulmonarius), microalgae (Chlorella vulgaris), and…
- Conditions
- Gastrointestinal Discomfort, Digestive Well Being, Gut-related Symptoms
- Trial name
- NCT07407777
- Testing
- Food ingredient of oyster mushroom mycelium (Pleurotus pulmonarius) and microalgae (Chlorella vulgaris)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Koralo GmbH
GERD (Gastroesophageal Reflux Disease)
Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of Smartphone Application GERDCare
Adherence to GERD treatment, including medication, diet, and lifestyle, is essential for symptom control and complication prevention, yet adherence rates remain low due to various demographic and clinical factors.
- Trial name
- AppGERD (NCT07127276)
- Testing
- Mobile application GERDCare
- Where
- Vietnam
- Volunteers
- 380 people
- Sponsor
- Institute of Gastroenterology and Hepatology, Vietnam
Cystic Fibrosis, Cystic Fibrosis Liver Disease
Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER)
RECOVER is a prospective, multicenter observational study designed to measure the real world clinical effectiveness of elexacaftor/tezacaftor/ivacaftor (ETI) triple combination therapy in people with cystic fibrosis initially…
- Conditions
- Cystic Fibrosis, Cystic Fibrosis Liver Disease, Cystic Fibrosis in Children, Adherence, Medication
- Trial name
- RECOVER (NCT04602468)
- Testing
- Elexacaftor/Tezacaftor/Ivacaftor
- Where
- 7 sites in Ireland, United Kingdom
- Volunteers
- 206 people
- Sponsor
- Royal College of Surgeons, Ireland
Gastric Cancer, Cancer Prevention
Personalised Health Recommendations to the General Population Through an Integrated AI Guided
This clinical study aims to be used to implement and validate the AIDA tool in two phases: Phase 1: Risk stratification and personalised recommendations \& Model development Phase 2: Mechanistic Model (Bioresource) development \&…
- Conditions
- Gastric Cancer, Cancer Prevention, Helicobacter Pylori Infection, Artificial Intelligence
- Trial name
- AIDA (NCT06421324)
- Testing
- Health reccommendations
- Where
- Spain
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Gastrointestinal Health
Colostrum and Gut Health
The primary objective of this study is to evaluate changes in participant-reported gastrointestinal function over a 16-week intervention period and a 4-week non-supplementation period (20 weeks total) following daily consumption…
- Trial name
- NCT07856979
- Testing
- Bovine Colostrum - Lower Dose, Bovine Colostrum - Higher Dose
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bovita Labs, LLC
Opioid Use Disorder, HIV Infections
Buprenorphine Integration Research and Community Health
The goal of this clinical trial is to evaluate an intervention strategy in introducing screen/evaluate/treat (SET) procedures for HIV/ hepatitis C/ and Opioid Use Disorder in Primary Care Clinics in West Virginia.
- Conditions
- Opioid Use Disorder, HIV Infections, Hepatitis C
- Trial name
- BIRCH (NCT05668780)
- Testing
- NIATx Coaching
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Food Labelling, Eating Behaviour
Food Menu Labelling Effects on Individuals With Eating Disorders and Other Mental Health Conditions.
Calorie labelling in out-of-home (OOH) settings was introduced by the government in England as part of a wider strategy to 'tackle obesity' (DHSC, 2020).
- Conditions
- Food Labelling, Eating Behaviour, Mental Health, Eating Disorder
- Trial name
- NCT07809295
- Testing
- Control condition, Calorie labelling, Nutri-Score labelling
- Where
- United Kingdom
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Cancer, Gastrointestinal Cancer
Quality of Care in Relationship to Aborted Cancer Surgery
Surgery is often a central curative treatment for gastrointestinal tumors. Surgical treatment of diagnosed cancer tumors is decided after a comprehensive assessment of the patient's physical status, radiological assessments and…
- Trial name
- NCT05808712
- Testing
- validation
- Where
- 2 sites in Sweden
- Volunteers
- 350 people
- Sponsor
- Linkoeping University
Hepatitis B, Human Papilloma Virus
Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health.
Aim: The main goal of this quantitative epidemiological observational study is to determine the prevalence of Human Papilloma Virus (HPV) infection and Hepatitis B (Hep B) immunity amongst women of childbearing age.
- Conditions
- Hepatitis B, Human Papilloma Virus, Mental Health Issue, Cancer Liver
- Trial name
- NCT06786429
- Testing
- Gardasil 9 vaccine, Hepatitis B Virus Vaccine(HBV), Cognitive Behavioral Therapy
- Volunteers
- 2,140 people, healthy volunteers welcome
- Sponsor
- Eunice Dube
Liver Fibrosis
City-Hospital Collaboration for Early Detection of Liver Fibrosis in Primary Care: A Secondary Prevention Project in the Grenoble Health Area
Cirrhosis and hepatocellular carcinoma (HCC) are responsible for 25,000 deaths per year in France. The main causes are excessive alcohol consumption, metabolic steatosis, and hepatitis B and C.
- Trial name
- PREFIB (NCT07031089)
- Testing
- Non-interventional study (RIPH category 3)
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Gastroesophageal Reflux, Patient Activation
Developing and Testing Mobile Health Question Prompt List in Gastroesophageal Reflux Disease
More than 40% of patients with gastroesophageal reflux disease (GERD) experience uncontrolled, chronic symptoms. This proposal aims to improve symptom control for patients with GERD, by developing a mobile health (mHealth)…
- Trial name
- NCT05900687
- Testing
- Use of mHealth Question Prompt List app
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University
Liver Metastases From Colorectal Cancer
Liver-First, Bowel-First, or Simultaneous Resection for Synchronous Colorectal Liver Metastases: Outcomes, Quality of Life, and Cost-Effectiveness
The goal of this observational study is to learn about treatment outcomes, quality of life, and healthcare costs in patients with colorectal cancer who have liver metastases detected at the same time as their primary tumor…
- Trial name
- OPTIMAL (NCT07564284)
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet