Clinical trials: Digestive System Fistula
Pancreatic Cancer, Pancreaticoduodenal; Fistula
Early Detection of Anastomotic Leakage by Microdialysis Catheters
Anastomotic leakage of the pancreatojejunostomy is often discovered with considerable delay, causing severe peritonitis, hemorrhage due to erosion of vessels, sepsis, and death.
- Conditions
- Pancreatic Cancer, Pancreaticoduodenal; Fistula, Pancreas; Fistula, Pancreatic Fistula
- Trial name
- NCT03627559
- Testing
- Pancreaticoduodenectomy microdialysis catheter analyses
- Volunteers
- 35 people
- Sponsor
- Oslo University Hospital
Oesophageal Atresia With Tracheo-Oesophageal Fistula, Tracheomalacia
Primary Posterior Tracheopexy Prevents Tracheal Collapse
Introduction: Children born with a blind-ending gullet (oesophagus), or Oesophageal Atresia (OA), need to undergo surgical correction in the first week of life.
- Conditions
- Oesophageal Atresia With Tracheo-Oesophageal Fistula, Tracheomalacia, Oesophageal Atresia
- Trial name
- PORTRAIT (NCT06335862)
- Testing
- Randomisation between the PPT- and no-PPT-group, Primary Posterior Tracheopexy, Preoperative tracheobronchoscopy
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 78 people
- Sponsor
- UMC Utrecht
Pancreatic Fistula
Prophylactic Pancreatic Stent for the Prevention of Post Operative Pancreatic Fistula
Postoperative pancreatic fistula (POPF) remains one of the most harmful complications after pancreatic resection. Some studies have indicated that endoscopic pancreatic stenting was effective in the treatment of POPF.
- Trial name
- NCT03822676
- Testing
- Prophylactic pancreatic stent
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Peking Union Medical College Hospital
Transsphincteric Anal Fistula
Ligation of Intersphincteric Track (LIFT) Versus Fistulectomy in Trans-sphincteric Anal Ffistula.
78 patients with transsphincteric fistula allocated into two groups group A underwent LIFT group B u nderwent fistulectomy , comparison between the outcome og both procedures
- Trial name
- professor (NCT04351074)
- Testing
- LIFT, fistulectomy
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Zagazig University
Omental Patch, Laparoscopic Pancreaticoduodenectomy
A Modified Omental Patch Work Decreases Pancreatic Fistula After Lpd
Pancreaticoduodenecotmy(PD) is considered as the standard procedure for peri-amplullary or pancreatic head tumors. Laparoscopic pancreaticoduodenctomy(LPD) has been reported with minimal invasive advantages, such as small…
- Conditions
- Omental Patch, Laparoscopic Pancreaticoduodenectomy, Pancreatic Fistula
- Trial name
- NCT04704882
- Testing
- omental patchwork
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhejiang Provincial People's Hospital
Recto Vaginal Fistula
Transperineal Repair of Primary Obstetric Rectovaginal Fistulas
Introduction: A rectovaginal fistula (RVF) is an epithelium-lined abnormal tract between the rectum and the vagina and is often a challenging problem for both the patients and to the surgeons.
- Trial name
- NCT04267757
- Testing
- rectovaginal fistula repair with Martius flap
- Where
- Egypt
- Volunteers
- 4 people
- Sponsor
- Zagazig University
Pancreatic Trauma, Pancreatic Duct Injury
A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes
The goal of this observational study is to compare the presentation, treatment, and outcomes in patients suffering traumatic pancreatic injuries from blunt or penetrating trauma. The questions this study aims to answer are: 1.
- Conditions
- Pancreatic Trauma, Pancreatic Duct Injury, Pancreas Necrosis, Pancreas Cyst
- Trial name
- NCT06227871
- Testing
- Exploratory laparotomy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Kern Medical Center
Pancreatic Cancer, Sepsis
Colonization of Bile Ducts and Postoperative Infectious Complications of Pancreaticoduodenectomies
The aim of the present prospective study was, first, to verify the correlation between biliary colonization and postoperative infectious complications, and secondarily to asses morbidity and mortality for patients who underwent…
- Conditions
- Pancreatic Cancer, Sepsis, Bile Duct Cancer, Duodenal Cancer
- Trial name
- NCT03525067
- Testing
- Bile sampling for bacterial examination
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Central Hospital, Nancy, France
Perianal Fistula Due to Crohn's Disease, Fistula in Ano
Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas w/ Crohn's Disease
Objectives: Primary: To demonstrate the safety of allogeneic UC-MSCs administered by injection for complex perianal fistulas in patients with Crohn's disease Secondary: To determine the efficacy of a single/multiple allogeneic…
- Trial name
- NCT05039411
- Testing
- PF2020-CELL (UC-MSCs) - Allogeneic Human Umbilical Cord Mesenchymal Stem Cells
- Where
- Malaysia
- Volunteers
- 5 people
- Sponsor
- CryoCord Sdn Bhd
Anal Fistula
Treatment of Perianal Fistulas by Endorectal Advancement Flap Associated With Adipose Tissue Injection
The study aims to evaluate effectiveness of the association of endorectal advancement flap technique with local injection of autologous and micro-fragmented adipose tissue, obtained with the Lipogems® system, in patients with…
- Trial name
- Fistula_CM1 (NCT04750499)
- Testing
- Adipose tissue injection associated with endorectal advancement flap.
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Hospital Clinic of Barcelona
Endothelial Degeneration, Pancreatic Cancer
Glycocalyx Levels in Patients Undergoing Pancreatectomy
Background: On the surface of every healthy cellular membrane resides a layer known as the glycocalyx. This structure consists of extracellular domains of receptor, adhesion and transmembrane molecules such as syndecan-1…
- Conditions
- Endothelial Degeneration, Pancreatic Cancer, Pancreatectomy, Postoperative Pancreatic Fistula
- Trial name
- NCT04058236
- Testing
- human albumin 5%, gelofusine.
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
Fistula in Ano
Two Approaches to Lower the Chances of Recurrence of Anal Fistula After Surgery
A total of 80 patients with complex fistula in ano of both genders were included. All patients in Group A underwent a loose seton technique.
- Trial name
- NCT06380036
- Testing
- video assisted fistula tract surgery
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sairah Sadaf
Anal Fistula, Crohn Disease
Management of Anal Fistula of Crohn Disease
The management of anal fistula in Crohn Disease is complex. In aim to obtain the healing of the anal fistula, different approaches can be proposed but the best strategy is not yet determined.
- Trial name
- FISTUCROHN (NCT03878498)
- Testing
- therapeutic management
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Rennes University Hospital
Fistula-In-Ano, Anal Fistula
Treatment of Anal Fistula With Lasercoagulation
The purpose of this study is to determine whether treatment with laser coagulation is an effective and safe treatment option for patients with anal fistula
- Trial name
- NCT03017898
- Testing
- Laser Coagulation
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Region Skane
Anal Fistula
Ligation of the Intersphincteric Fistula Tract (LIFT) + Biodesign for Anal Fistula
The LIFT+Biodesign® study is a post-market observational study to evaluate the rate of fistula closure in patients with persistent trans-sphincteric anal fistula who receive the Biodesign® Tissue graft as part of their LIFT…
- Trial name
- LIFT+Graft (NCT01602081)
- Testing
- reinforce soft tissue
- Where
- 8 sites in United States
- Volunteers
- 28 people
- Sponsor
- Cook Group Incorporated
Recto-vaginal Fistula
Stromal Vascular Fraction (SVF) for Treatment of Recto-vaginal Fistula
The purpose of this study is to determine safety of Stromal Vascular Fraction (SVF) for the treatment of recto-vaginal fistula.
- Trial name
- HULPCIR (NCT01548092)
- Testing
- Adipose-derived stem cells without expanded
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Pancreatic Cancer
Predicting Pancreatic Fistula After Pancreatic Surgery Using Preoperative Immunity
The goal of this observational study is to develop and validate a preoperative immunological signature for predicting postoperative pancreatic fistula (POPF) in adult patients undergoing pancreatic surgery for pancreatic cancer.
- Trial name
- NCT07827911
- Testing
- blood sampling
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Institut Paoli-Calmettes
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Fistula; Sigmoid
Endoscopic Management Of Controlled Colo-cutaneous Fistula As A Complication of Acute Sigmoid Diverticulitis: A Randomized Controlled Trial
Diverticular disease is a common condition in western countries with relatively uncommon complications[1]. Fistulae complicating diverticulitis are the result of a localized perforation into adjacent viscera, and occur in 4-23%…
- Trial name
- NCT05834985
- Testing
- endoscopic management of fistula due to sigmoid diverticulitis by clip or endostitches
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Zagazig University
Short Bowel Syndrome, Intestinal Fistula
Intralipid Versus SMOFlipid in HPN Patients
This study will randomize all patients who are new to the Mayo Clinic HPN team to either standard lipid emulsion (Intralipid) or SMOFLipid.
- Conditions
- Short Bowel Syndrome, Intestinal Fistula, Crohn Disease, Intestinal Obstruction
- Trial name
- NCT03773237
- Testing
- SMOFLipid, Intralipid
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Mayo Clinic