Clinical trials: Digestive System Surgical Procedures
Cholecystitis, Stress
The Effect of the Stress Ball Applied Before Colocystectomy Surgery on Patients; Surgical Fear, Anxiety and Comfort.
Cholecystectomy is the most common major abdominal surgical procedure in western countries. Patients may experience fear and anxiety before surgery.
- Conditions
- Cholecystitis, Stress, Fear, Comfort
- Trial name
- NCT06345768
- Testing
- Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Sleep Apnea, Hypertension
Tri Staple Technology Stapler Used in Gastric Bypass
The objectives of this clinical trial are to assess in a pilot setting the overall performance and safety of the Endo GIA™ Stapler with Endo GIA™ SULU with Tri-Staple™ Technology when used in a gastric bypass procedure.
- Conditions
- Sleep Apnea, Hypertension, Hyperlipidemia, Coronary Artery Disease
- Trial name
- NCT01026103
- Testing
- Tri Staple Technology stapler
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Fistula in Ano
Management of Fistula in Ano by Kshar Sutra, Para Surgical Procedure.
Background: Fistula in ano is one of the most common diseases of the ano rectal region. Treatment of Fistula in ano has puzzled the medical fraternity due to its complex nature.
- Trial name
- Bhagandar (NCT01880398)
- Testing
- Kshar Sutra
- Where
- India
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Government Ayurved College and Hospital
Chronic Pancreatitis
Endoscopic Ultrasound (EUS) Features of Chronic Pancreatitis
The purpose of this study is to correlate Endoscopic Ultrasound (EUS) criteria for chronic pancreatitis with surgical pathology.
- Trial name
- NCT01442454
- Testing
- chronic pancreatitis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
GERD
A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors
Background: Gastroesophageal reflux disease (GERD), which affects at least 20% of adult Americans, may be especially common and severe in Veteran patients.
- Trial name
- NCT01265550
- Testing
- Nissen fundoplication, baclofen, Desipramine
- Where
- 15 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Rectal Cancer, Retention, Urinary
Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary Catheter Removal in Patients With Rectal Resection
DESIGN: Randomized, open-label and parallel clinical trial, assigned to early, mid, or late withdrawal of urinary catheter with a 1: 1: 1 allocation ratio.
- Conditions
- Rectal Cancer, Retention, Urinary, Urinary Tract Infections, Surgical Site Infection
- Trial name
- RAOREC (NCT04751149)
- Testing
- Removal of Urinary Catheter
- Where
- Spain
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Hospital Donostia
Hepatocellular Carcinoma
A Trial of Adjuvant Transarterial Chemoembolization (TACE) for Preventing Tumor Recurrence After Liver Resection
The aim of this study is to analyze the therapeutic effect of adjuvant TACE after resection.Patients receiving curative resection (R0) were randomized to postoperative TACE group and no TACE group.
- Trial name
- NCT00820053
- Testing
- epirubicin and lipiodol
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Esophageal Squamous Cell Carcinoma, Esophagectomy
Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 Years
To determine whether older patients who underwent esophagectomy had better outcome survival than those who were non-surgically treated.
- Conditions
- Esophageal Squamous Cell Carcinoma, Esophagectomy, Radiotherapy, Chemotherapy
- Trial name
- NCT05604950
- Testing
- Since the data were collected retrospectively, there were no interventions
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Yongtao Han
Acute Appendicitis
Appendicectomy Versus Antibiotics in the Treatment of Acute Uncomplicated Appendicitis
Appendicectomy has been the treatment of acute appendicitis for over a hundred years. Appendicectomy, however, includes operative and postoperative risks despite being a "routine" operation.
- Trial name
- APPAC (NCT01022567)
- Testing
- Appendicectomy, Ertapenem
- Where
- 6 sites in Finland
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Colorectal Cancer
Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery
This is a prospective randomized study to evaluate the difference in the rate of surgical site infection between the patients who used Sodium Picosulfate solution(PicosolutionⓇ) and tablet Oral Sulphate Solution(ORA·FANGⓇ) for…
- Trial name
- NCT04593446
- Testing
- Oral Sulfate Tablet(ORA·FANGⓇ), Sodium Picosulfate Solution(PicosolutionⓇ)
- Where
- South Korea
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Perianal Fistula, Crohn Disease
Surgical Closure vs Anti-TNF in the Treatment of Perianal Fistulas in Crohn's Disease (PISA-II): a Comprehensive Cohort Design
Currently, the treatment of Crohn's patients with perianal fistulas predominantly exists of anti-TNF medication. However, its efficiency has never been directly compared to surgical closure of the perianal fistula.
- Trial name
- PISA-II (NCT06441526)
- Testing
- anti-tumour necrosis factor α antibodies, Advancement plasty
- Where
- Netherlands
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Gallstone, Cholecystitis
A Clinical Study of Chinese Domestic Surgical Robot
This is a prospective, multi-center, randomized, single-blind, parallel-controlled clinical trial to evaluate the safety and efficacy of the Chinese domestic endoscopic instrument control system in clinical treatment.
- Trial name
- NCT04122261
- Testing
- the MicroHand S endoscopic instrument control system, the da Vinci endoscopic instrument control system
- Where
- China
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Colorectal Cancer, Surgical Procedure, Unspecified
Perioperative Management of Colorectal Cancer Patients Infected With COVID-19: a Multicenter Prospective Cohort Study.
This trial is a multicenter prospective cohort study to explore timing of colorectal cancer surgery after COVID-19 infection so that can assist clinicians and patients.
- Trial name
- NCT05682898
- Testing
- Timing of colorectal cancer surgery
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Hemorrhoids
Laser Hemorrhoidoplasty Versus Open Surgical Hemorrhoidectomy in Second and Third Degree Piles
The study aims to compare the pain , duration of intervention and long term outcomes of laser hemorrhoidoplasty versus open surgical hemorrhoidectomy
- Trial name
- NCT05770141
- Testing
- laser hemorrhoidoplasty, open surgical hemorrhoidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Appendicitis Acute
Surgical Site Infiltration Using Ketamine Versus Bupivacaine for Analgesia in Post-operative Appendectomy Operation
surgical site infiltration using ketamine versus Bupivacaine for analgesia in post-operative Appendectomy operation by Ketamine versus Bupivacaine
- Trial name
- NCT05097118
- Testing
- Ketamine Versus Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Endometriosis
ENDOMET - Novel Diagnostic Tools and Treatments for Endometriosis
Endometriosis is a chronic disease characterized by the presence of functional endometrial glands and stroma in ectopic locations outside the uterine cavity.
- Trial name
- ENDOMET (NCT01301885)
- Testing
- Laparoscopy/laparotomy
- Where
- 4 sites in Finland
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Pancreatic Fistula, Distal Pancreatectomy Complications
An Evaluation of a New Technique Utilizing a Biologic Glue and Tissue Patch to Seal the Cut Edge of the Pancreas Following Removal of the Tail of the Pancreas
The purpose of this trial is to determine whether the use of an autologous falciform ligament patch combined with fibrin glue will reduce the rate of pancreatic fistula in patients completing distal pancreatectomy.
- Conditions
- Pancreatic Fistula, Distal Pancreatectomy Complications, Falciform Patch Pancreatic Closure, Fibrin Glue Pancreatic Closure
- Trial name
- NCT00889213
- Testing
- Falciform patch and fibrin glue application, standard pancreatic closure
- Where
- 2 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Colon Cancer, Colitis
Novel Listeria Vectors Secreting Gut Flora-Altering Agents to Prevent Colon Cancer and Treat Colitis
This is a simple tissue collection study with no therapeutic intent. Colon tissues will be taken from standard of care procedures.
- Trial name
- NCT03014284
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Liver Neoplasms, Sarcopenia
Impact of Sarcopenia on Postoperative Outcomes of Patients Undergoing Liver Resection
The investigators will investigate the impact of different biometric parameters (Body mass index, sarcopenia, lean muscle mass, hand-grip strength, gait speed, fat composition) on the postoperative outcomes of patients undergoing…
- Conditions
- Liver Neoplasms, Sarcopenia, Postoperative Complications
- Trial name
- NCT03630978
- Testing
- Liver resection
- Where
- Italy
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- San Camillo Hospital, Rome