Clinical trials: Digital
Depression, Depressive Symptoms
Evaluation of a Proactive Identification and Digital Mental Health Intervention Approach to Address Unmet Psychosocial Needs of Individuals Living With Cancer
The purpose of this research study is to evaluate a mobile application (app) for depression treatment called "Moodivate" among cancer survivors.
- Conditions
- Depression, Depressive Symptoms, Cancer
- Trial name
- NCT05932810
- Testing
- Behavioral Activation Therapy app, Treatment as Usual
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Implementation, Behavioral Symptoms
Working to Implement and Sustain Digital Outcome Measures
This study will investigate the effects of an organizational implementation strategy called Leadership and Organizational Change for Implementation (LOCI), relative to training and technical assistance only, on fidelity to, and…
- Trial name
- WISDOM (NCT04096274)
- Testing
- Leadership for Organization Change and Implementation (LOCI), Training and Technical Assistance Only
- Where
- 4 sites in United States
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- Boise State University
Colorectal Cancer Screening
Feasibility of a Colorectal Cancer Screening Web App in Primary Care Patients
The goal of this clinical trial is to test the feasibility of a web app about colorectal cancer screening in patients with an upcoming primary care appointment.
- Trial name
- NCT06241768
- Testing
- mPATH-CRC Web app
- Where
- United States
- Volunteers
- 921 people
- Sponsor
- Digital Health Navigation Solutions, Inc
Cardiovascular Diseases, Diabetes
Diabetes Remote Intervention to improVe Use of Evidence-based Medications
A randomized remote, implementation trial in the Mass General Brigham network was performed on 200 patients with T2D at high CV or kidney risk.
- Trial name
- DRIVE (NCT06046560)
- Testing
- SGLT2 inhibitor, GLP-1 RA, Education-First
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Stroke
Stroke Team Remote Evaluation Using a Digital Observation Camera
The purpose of this trial is to determine if an experimental remote video camera system is an effective way for a stroke specialist to evaluate stroke patients from a distant site.
- Trial name
- STRokE DOC (NCT00283868)
- Where
- 4 sites in United States
- Volunteers
- 234 people
- Sponsor
- University of California, San Diego
Bone Marrow Transplant, Information Disclosure
Effects of Digital Stories Intervention on Psychosocial Well-being
Patients and caregivers undergoing hematopoietic stem cell transplantation often continue to experience anxiety, depression, isolation, and other psychosocial distress.
- Conditions
- Bone Marrow Transplant, Information Disclosure, Hematopoietic Stem Cell Transplantation, Psychosocial Health
- Trial name
- NCT03654599
- Testing
- Baseline Surveys, Digital Stories Intervention, Information Control Intervention
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Arizona State University
Obsessive-Compulsive Disorder
Digital Health Interventions for Obsessive Compulsive Disorder (OCD)
The investigators are testing two digital health interventions for obsessive compulsive disorder (OCD). The investigators hope that these digital health programs will increase access to treatment for OCD.
- Trial name
- NCT04136626
- Testing
- Perspectives OCD, The Health and Well-Being Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Anxiety, COVID-19 Pandemic
SMILE: Clinical Trial to Evaluate Mindfulness as Intervention for Racial and Ethnic Populations During COVID-19
The goal of this clinical trial is to evaluate the SMILE app, a Digital Health Platform (DHP), that will deliver a mindfulness intervention, designed to mitigate COVID-19 related stress.
- Trial name
- SMILE (NCT06242080)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of North Carolina, Chapel Hill
Pregnancy Related, Postpartum Sadness
Fourth Trimester - A Web-based Tool for Postpartum Care to Address the Needs of Underserved Women
The postpartum period is a critical time for both maternal and child health, and more than half of all maternal deaths occur postpartum, from one day to one year after birth.
- Trial name
- NCT04475718
- Testing
- Fourth Trimester Mobile Tool
- Where
- 2 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Opioid-use Disorder, Anxiety Disorders
Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder
The majority of opioid users meet criteria for anxiety and depressive disorders, but most substance use disorder treatment programs do not offer treatment for co-occurring mental health problems.
- Conditions
- Opioid-use Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT05047627
- Testing
- Smartphone-Based Digital Intervention
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Trustees of Dartmouth College
Schizophrenia, Schizoaffective Disorder
A Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals and Adults With Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis on an Oral Atypical Antipsychotic
Digital medicine systems (DMS) have been designed to assist individuals with the management of their daily health, wellness, and medication use.
- Conditions
- Schizophrenia, Schizoaffective Disorder, First Episode Psychosis
- Trial name
- NCT03568500
- Testing
- Digital Medicine System, Aripiprazole, Olanzapine
- Where
- 5 sites in United Kingdom
- Volunteers
- 44 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Opioid-use Disorder
OXD01 in Combination With Sublingual Buprenorphine/Naloxone for Treatment of Opioid Use Disorder
This is an open-label, randomized, parallel-group multicenter study designed to evaluate the efficacy of the digital therapeutic OXD01 (MODIA) combined with sublingual buprenorphine/naloxone standard of care (SL BUP/NAL SOC)…
- Trial name
- NCT04948307
- Testing
- OXD01 digital therapy, Standard of Care
- Where
- 21 sites in United States
- Volunteers
- 437 people
- Sponsor
- Orexo AB
Fibromyalgia
"SMART-FM": Smart-Phone Based Digital Therapeutic for Management of Fibromyalgia
This is a non-significant risk, multi-center, randomized, active-controlled study to compare the effectiveness of two digital therapies in the management of fibromyalgia over 12 weeks.
- Trial name
- SMART-FM (NCT05005351)
- Testing
- Digital ACT, Digital Symptom Tracker
- Where
- 7 sites in United States
- Volunteers
- 67 people
- Sponsor
- Swing Therapeutics, Inc.
Breast Cancer
Intra-operative Digital vs. Standard Mammography
A breast biopsy in the operating room may be needed in up to 15% of patients with an abnormality on mammogram. When an abnormality is present but there is no palpable mass, the abnormality must be localized with a wire before…
- Trial name
- NCT01766102
- Testing
- Intra-operative Mammography, Standard Mammography
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
Respiratory Complication, Obstructive Sleep Apnea
Applying Best Clinical Practices to Patients at High Risk of Respiratory Complications
The purpose of this study is to: 1. Perform a retrospective analysis on data contained in the UCLA Perioperative Data Warehouse on the incidence of respiratory dysfunction in the post-operative care unit (PACU) before and after…
- Trial name
- NCT04263363
- Testing
- Sugammadex 100 MG/ML [Bridion]
- Where
- United States
- Volunteers
- 12,248 people
- Sponsor
- University of California, Los Angeles
Chronic Pain, Exposure
Agile Development of a Digital Exposure Treatment for Youth With Chronic Musculoskeletal Pain
This project proposes to systematically develop and evaluate the feasibility and preliminary effectiveness of a digitally delivered, graded exposure treatment for youth with chronic musculoskeletal pain, utilizing a sequential…
- Conditions
- Chronic Pain, Exposure, Adolescent Behavior, Child Behavior
- Trial name
- NCT05079984
- Testing
- Graded exposure treatment (GET)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Stanford University
Cognitive Functioning of Healthy Individuals
Psychometric Properties of IntelliSpace Cognition
This study aims to validate the tests that are on the IntelliSpace Cognition platform and to establish normative data for these tests.
- Trial name
- NCT03801382
- Testing
- IntelliSpace Cognition (ISC), Paper-Pencil Tests
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Sleep, Psychiatric Health
Sustainable Habits for Encouraging Even Teen Sleep
This study will examine the feasibility, acceptability, and effectiveness of two digital sleep interventions in improving sleep regularity and psychiatric health during a critical period of adolescence.
- Trial name
- SHEETS (NCT05378373)
- Testing
- Garmin, Pattern Health App
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Duke University
Attention Deficit Disorder With Hyperactivity
Software Treatment for Actively Reducing Severity of ADHD
The purpose of this study is to evaluate the effects of videogame-like digital therapies on attentional functioning and symptoms in children diagnosed with ADHD.
- Trial name
- STARS-ADHD (NCT02674633)
- Testing
- AKL-T01, AKL-T09
- Where
- 20 sites in United States
- Volunteers
- 348 people
- Sponsor
- Akili Interactive Labs, Inc.
Family Caregivers, Insomnia
Optimizing Efficiency and Impact of Digital Health Interventions for Caregivers
The overall objective of this mixed-methods proposal is to answer the focused research question: What tailoring is necessary and sufficient to achieve optimal engagement with and efficacy of Sleep Healthy Using the Internet…
- Conditions
- Family Caregivers, Insomnia, Sleep Initiation and Maintenance Disorders
- Trial name
- NCT04986904
- Testing
- SHUTi (Sleep Healthy Using the Internet)
- Where
- 2 sites in United States
- Volunteers
- 102 people
- Sponsor
- University of Virginia