Clinical trials: Digital Nerve Injury
Digital Nerve Injury
TISSIUM's Nerve Coaptation Device First-in-Human Clinical Trial
The purpose of this study is to collect initial safety and device performance data of the TISSIUM's nerve coaptation device for the sutureless repair of digital nerve injuries of the hand in which there has been no substantial…
- Trial name
- NCT04327154
- Testing
- TISSIUM™ Nerve Coaptation Device
- Where
- 2 sites in Australia
- Volunteers
- 12 people
- Sponsor
- Tissium
Digital Nerve Injury
SECURE Post-Market Study
The purpose of this post-market study is to generate post-market, real- world evidence on the safety and performance of COAPTIUM® CONNECT with TISSIUM® LIGHT for the atraumatic sutureless repair of acute digital (sensory)…
- Trial name
- SECURE PMS (NCT07756489)
- Testing
- COAPTIUM® CONNECT
- Volunteers
- 65 people
- Sponsor
- Tissium
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford
Transplantation
Innervated Sensory Cross-Finger Flap
The purpose of this study is to introduce a new operative technique for reconstruction of fingertip degloving injury.
- Trial name
- ISCF (NCT01019811)
- Testing
- The innervated sensory cross-finger flap
- Where
- China
- Volunteers
- 16 people
- Sponsor
- The Second Hospital of Tangshan
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Laceration of Skin, Anesthesia, Local
Double-dorsal Versus Single-volar Digital Block
The aim of this study is to compare the traditional dorsal double injection digital block with the palmar single injection technique in the suturing of acute traumatic hand finger lacerations in terms of injection pain score…
- Conditions
- Laceration of Skin, Anesthesia, Local, Pain, Nerve Block
- Trial name
- NCT06274073
- Testing
- Dorsal digital block, Palmar digital block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara City Hospital Bilkent
Flaccid Paresis, Spastic Paresis
Comparing Digitally and Traditionally Made Ankle Foot Orthoses
The research is being done to compare two methods of creating AFOs: 1. The traditional method, which involves manually creating a mold from a plaster cast of the client's limb. This is time-consuming and labor-intensive; and 2.
- Conditions
- Flaccid Paresis, Spastic Paresis, Cerebral Palsy, Stroke
- Trial name
- NCT06828653
- Testing
- Part A First Wear Period: Traditional AFO(s), Part A First Wear Period: Digital AFO(s), Part A Second Wear Period: Traditional AFO(s)
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Traumatic Nerve Injury
A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options
This study is a comparison of sensory recovery outcomes following the use of AVANCE Nerve Graft or hollow tube conduit for peripheral nerve gap repairs in the hand.
- Trial name
- CHANGE (NCT00948025)
- Testing
- Hollow tube nerve conduit, synthetic or biosynthetic, Processed Human Nerve Tissue
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Axogen Corporation
Peripheral Nerve Injury, Nerve Injury
Polyethylene Glycol to Improve Sensation Following Digital Nerve Laceration
PEG is a fusogen, a type of chemical that aids in mediating cell fusion. PEG helps nerve cells recover neuronal continuity by removing plasmalemmal-bound water which opens the axonal ends on both sides of the injury.
- Trial name
- NCT04270019
- Testing
- Polyethylene Glycol 3350, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Digital Nerve Injury
Cast Or ePineural Suture for Digital Nerve Injuries - a Randomised Controlled Study
Nerve injury in the fingers is a common injury and affects people of all ages. The treatment usually offered to patients is surgery and various types of rehabilitation.
- Trial name
- COPS (NCT05536609)
- Testing
- Epineural suture, Non-operative treatment
- Where
- Sweden
- Volunteers
- 166 people
- Sponsor
- Karolinska Institutet
Digital Nerve Injuries
Sensory Recovery of Digital Nerves After Microsurgical Epineural Neurorrhaphy Alone or in Combination With Tisseel - RET
Evaluation of sensitivity after primary surgical treatment of digital nerve injuries with microsurgical epineural end-to-end neurorrhaphy alone or in combination with the fibrin glue Tisseel®
- Trial name
- RET (NCT05490940)
- Testing
- Tisseel®
- Where
- Switzerland
- Volunteers
- 74 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Finger Injuries, Procedural Pain
Topical Lidocaine for Digital Nerve Block Pain
The goal of this clinical trial is to determine whether topical lidocaine spray applied to the wound before digital nerve block can reduce injection-related pain in patients with finger lacerations.
- Trial name
- NCT07834866
- Testing
- Topical Lidocaine Spray
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Ankara City Hospital Bilkent
Digital Nerve Injury
Vitamin D3 in Sensory Recovery After Digital NERVe Suture (D3NERV).
Digital nerve injuries are frequent in a FESUM center (Federation Européenne des Services d'Urgences Mains), and they need to be repaired in order to reduce the risk of hypoesthesia and to prevent painful neuroma.
- Trial name
- D3NERV (NCT04115982)
- Testing
- Cholecalciferol
- Where
- 3 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
The Comorbidity Between the Trigger Digit and Carpal Tunnel Syndrome
Investigation of the Relation Between Trigger Digit and Carpal Tunnel Syndrome
The purpose of this study is to comprehend the association between the trigger digit and carpal tunnel syndrome based on the quantification of the tendon and nerve characteristics. It includes three parts.
- Trial name
- NCT04072692
- Testing
- Hybrid rehabilitation training, Traditional rehabilitation training, Wearable anti-bowstringing orthosis (WABO)
- Where
- Taiwan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Reliability of Sensory Neurography and S2PD
Sensory Neurography and S2PD, a Test-Retest Study
This study was conducted as a test-retest investigation to assess the reliability of the methods prior to a planned study on the same topic.
- Trial name
- NCT07605585
- Testing
- S2PD, Sensory neurography
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Comparison Between Ultrasound and Clinical Measurements
The Use of Novel us Device (Jetguide) to Measure the Distance to the Roof of the IAC (Inferior Alveolar Canal)
The purpose of this human clinical trial is to validate the accuracy of Jetguide® US device in detecting the inferior alveolar canal (IAC) and to compare it to measurements performed on computerized tomography images.
- Trial name
- NCT01505335
- Testing
- US depth measurements
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Rambam Health Care Campus
Carpal Tunnel Syndrome, Patient Satisfaction
Postoperative Care After Carpal Tunnel Release Using Short Educational Videos
The goal of this clinical trial is to learn if a patient-directed postoperative care program, using short educational videos, can improve patient satisfaction and reduce healthcare resource utilization in patients undergoing…
- Trial name
- VIDEO (NCT06647719)
- Testing
- Educational Videos
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Carilion Clinic
Anxiety, PTSD
Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health
RESYNC-BH is a research study evaluating a personalized, non-drug brain-and-body treatment approach for adults with ongoing behavioral health symptoms such as depression, anxiety, trauma-related symptoms, sleep problems…
- Conditions
- Anxiety, PTSD, ADHD, Depression Disorders
- Trial name
- RESYNC-BH (NCT07812987)
- Testing
- AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Tactical Mind Research Coalition, Inc.
Peripheral Nerve Injuries
REINVENT Registry (Registry of the Nerve Gap Repair From Integra)
This is a prospective, multi-center, observational registry designed to evaluate two of Integra's collagen nerve gap repair products (NeuraGen® Nerve Guide and NeuraGen® 3D Nerve Guide Matrix).
- Trial name
- NCT05339594
- Testing
- NeuraGen, NeuraGen 3D
- Where
- 6 sites in United States
- Volunteers
- 17 people
- Sponsor
- Integra LifeSciences Corporation
This Study is Testing the Use of MatriDerm
Nerve Grafting Using MATRIderm® in Traumatic Digital Nerve Injuries: a Randomized, Single-center, Controlled Study
Hand and wrist injuries are very common, with nearly 2 million cases each year in France. Many injuries involve cuts that damage important structures such as nerves, tendons, blood vessels, bones, or joints.
- Trial name
- MATRINERVE (NCT07292415)
- Testing
- Standard peripheral nerve repair under regional anesthesia with magnification; epineural sutures placed, followed by 2-week immobilization if needed., Peripheral nerve repair under regional anesthesia with epineural sutures; nerve wrapped along its length with 1 mm MatriDerm® collagen-elastin matrix before standard skin closure.
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Nice