Clinical trials: Digital Nerve Injury
Nerve Injury, Digital Pulp Defect
Free Dorsal Digital Flap for Reconstruction of Volar Soft Tissue Defect of Digits
The aim of the current report is to investigate the feasibility of transferring the free dorsal digital flap, including both dorsal branches of the proper digital nerves (PDNs), to reconstruct the volar soft tissue defect of…
- Trial name
- NCT01533337
- Testing
- Free dorsal digital flap
- Volunteers
- 12 people
- Sponsor
- The Second Hospital of Tangshan
Carpal Tunnel Syndrome (CTS)
Diagnostic Value of Digital Infrared Thermographic Imaging in Diagnosing Carpal Tunnel Syndrome
The goal of this observational study is to evaluate skin temperature patterns measured by infrared thermography in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT07699289
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Digital Nerve Injury
NeuraGen 3D Pilot Study
This is a 10-subject, 12-month follow-up, prospective, multi-center, open-label, single arm clinical trial designed to understand the initial performance characteristics and confirm the safety profile of the NeuraGen 3D Nerve…
- Trial name
- NCT05343143
- Testing
- NeuraGen 3D Nerve Guide Matrix
- Where
- 4 sites in United States
- Volunteers
- 1 people
- Sponsor
- Integra LifeSciences Corporation
Peripheral Nerve Injury Digital Nerve Hand
Evaluate the Reconstruction of Digital Nerve Defects in Humans Using an Implanted Silk Nerve Guide
The goal of this study is to ascertain the feasibility and safety of the procedure using SilkBridge - a biocompatible silk fibroin-based scaffold - for the regeneration of sensory nerve fibres and follow it up together with the…
- Trial name
- NCT03673449
- Testing
- SilkBridge
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Silk Biomaterials srl
Trauma
Sensory Reconstruction of Finger Pulp Defect Using a Dorsal Digital Island Flap
Sensory reconstruction of the finger pulp is a challenging problem. This article reports repair of the finger pulp defect using the dorsal digital island flap.
- Trial name
- NCT01486719
- Testing
- Sensate Dorsal Digital Island Flap
- Volunteers
- 12 people
- Sponsor
- The Second Hospital of Tangshan
Digital Nerve Injury
Vitamin D3 in Sensory Recovery After Digital NERVe Suture (D3NERV).
Digital nerve injuries are frequent in a FESUM center (Federation Européenne des Services d'Urgences Mains), and they need to be repaired in order to reduce the risk of hypoesthesia and to prevent painful neuroma.
- Trial name
- D3NERV (NCT04115982)
- Testing
- Cholecalciferol
- Where
- 3 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
Injury of Nerves at Wrist and Hand Level
A Phase I Trial of a Novel Synthetic Polymer Nerve Conduit 'Polynerve' in Participants With Sensory Digital Nerve Injury
Participants with a traumatic sensory nerve injury in the hand will be recruited to the study. Participants found to have a nerve gap of at least 5 mm and no greater than 20mm will undergo repair with the Polynerve.
- Trial name
- UMANC (NCT02970864)
- Testing
- Polynerve
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Manchester
Anxiety, PTSD
Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health
RESYNC-BH is a research study evaluating a personalized, non-drug brain-and-body treatment approach for adults with ongoing behavioral health symptoms such as depression, anxiety, trauma-related symptoms, sleep problems…
- Conditions
- Anxiety, PTSD, ADHD, Depression Disorders
- Trial name
- RESYNC-BH (NCT07812987)
- Testing
- AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Tactical Mind Research Coalition, Inc.
The Comorbidity Between the Trigger Digit and Carpal Tunnel Syndrome
Investigation of the Relation Between Trigger Digit and Carpal Tunnel Syndrome
The purpose of this study is to comprehend the association between the trigger digit and carpal tunnel syndrome based on the quantification of the tendon and nerve characteristics. It includes three parts.
- Trial name
- NCT04072692
- Testing
- Hybrid rehabilitation training, Traditional rehabilitation training, Wearable anti-bowstringing orthosis (WABO)
- Where
- Taiwan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Infection Wound, Disruption of Nerve Repair
Repair of Infective Wound Associated With Nerve Defect in the Finger Using A Bipedicled Nerve Flap
A combination of soft tissue and digital nerve defects in the finger results in sensory loss of the finger pulp. Reconstruction of these combined injuries is difficult.
- Trial name
- NCT01707654
- Testing
- Nerve flap
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Reliability of Sensory Neurography and S2PD
Sensory Neurography and S2PD, a Test-Retest Study
This study was conducted as a test-retest investigation to assess the reliability of the methods prior to a planned study on the same topic.
- Trial name
- NCT07605585
- Testing
- S2PD, Sensory neurography
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Laceration of Skin, Anesthesia, Local
Double-dorsal Versus Single-volar Digital Block
The aim of this study is to compare the traditional dorsal double injection digital block with the palmar single injection technique in the suturing of acute traumatic hand finger lacerations in terms of injection pain score…
- Conditions
- Laceration of Skin, Anesthesia, Local, Pain, Nerve Block
- Trial name
- NCT06274073
- Testing
- Dorsal digital block, Palmar digital block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara City Hospital Bilkent
Soft Tissue Injuries
Bilaterally Innervated Sensory Dorsal Digital Flaps for Sensory Reconstruction of the Fingers
Sensory coverage in the finger continues to be a challenging problem. This study reports sensory reconstruction of the fingers with the bilaterally innervated dorsal digital flaps and compares the results between the dual- and…
- Trial name
- NCT02167646
- Testing
- Flap including bilateral nerve branches
- Where
- China
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Traumatic Nerve Injury
A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options
This study is a comparison of sensory recovery outcomes following the use of AVANCE Nerve Graft or hollow tube conduit for peripheral nerve gap repairs in the hand.
- Trial name
- CHANGE (NCT00948025)
- Testing
- Hollow tube nerve conduit, synthetic or biosynthetic, Processed Human Nerve Tissue
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Axogen Corporation
Peripheral Nerve Injury Upper Limb
Reconstruction of Digital Nerve Lesions With Muscle-in-Vein Conduits
Muscle-in-vein conduits (MVCs) provide an alternative for bridging digital nerve defects when tension-free suture is not possible.
- Trial name
- NCT04788030
- Testing
- Nerve reconstruction
- Volunteers
- 37 people
- Sponsor
- BG Trauma Center Tuebingen
Peripheral Nerve Injuries, Sensory Deficit
The Effect of Pre-operative Electrical Stimulation on Peripheral Nerve Regeneration.
Traumatic injury to the peripheral nerves is most common in the young population with high associated costs to the patient, as well as to society. These range from acute healthcare cost to loss of productivity and rehabilitation.
- Conditions
- Peripheral Nerve Injuries, Sensory Deficit, Digital Nerve Lesion
- Trial name
- NCT03205124
- Testing
- Electrical Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Digital Nerve Injury
Cast Or ePineural Suture for Digital Nerve Injuries - a Randomised Controlled Study
Nerve injury in the fingers is a common injury and affects people of all ages. The treatment usually offered to patients is surgery and various types of rehabilitation.
- Trial name
- COPS (NCT05536609)
- Testing
- Epineural suture, Non-operative treatment
- Where
- Sweden
- Volunteers
- 166 people
- Sponsor
- Karolinska Institutet
Peripheral Nerve Injury Digital Nerve Hand Left
Optimization of Peripheral Nerve Reconstruction: A Non-inferiority Trial
1. To analyse the outcome of different treatment options of peripheral nerve repair with no gap (group 1) and with a critical sized (>5mm) defect (group 2) in order to optimize peripheral nerve repair 2.
- Trial name
- NCT01573650
- Where
- Switzerland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Pain, Acute, Pain, Chronic
Development and Validation of a Digital Pain-Reduction Kit for Musculoskeletal Injuries
This study will test the effectiveness of an evidence-based, multi-modal, "digital pain-reduction kit" as a non-pharmacological supplement to managing patients with pain due to musculoskeletal injuries.
- Trial name
- NCT03187132
- Testing
- Digital Pain Reduction Kit, Active Control
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- Cedars-Sinai Medical Center
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford