Clinical trials: Digital Tomosynthesis
Breast Cancer
Screening for Breast Cancer With Digital Breast Tomosynthesis
Randomized trial comparing the performance of tomosynthesis and 2D Digital Mammography vs 2D Digital Mammography only in respect to incidence of advanced cancers (interval and following round) and interval cancers.
- Trial name
- NCT02698202
- Testing
- Digital Breast Tomosynthesis
- Where
- Italy
- Volunteers
- 26,877 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Breast Cancer
Automated Breast Ultrasound as an Adjunct to Screening Digital Breast Tomosynthesis
The purpose of this study is to assess whether the Invenia™ Automated Breast Ultrasound (ABUS) device, as an adjunct to Digital Breast Tomosynthesis (DBT), improves breast cancer detection in women with dense breasts.
- Trial name
- AMELIA (NCT03616457)
- Testing
- Automated Breast Ultrasound (ABUS)
- Sponsor
- GE Healthcare
Breast Cancer
Digital 3D Breast Tomosynthesis Versus 2D in Clinical Evaluation of High Risk Women
Patients with a higher breast cancer risk (higher than 17% according to the IBIS calculation) will receive a 2D digital mammography together with a 3D tomosynthesis (so called combo tomo) of both breasts in two views in order to…
- Trial name
- NCT02209129
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Solitary Pulmonary Nodules
Clinical Evaluation of CARESTREAM Dual Energy and Digital Tomosynthesis
The purpose of this study is to evaluate the imaging performance of Dual Energy and Digital Tomosynthesis (DE-DT) application against the commercially available predicate devices.
- Trial name
- NCT02531646
- Testing
- Radiation
- Volunteers
- 66 people
- Sponsor
- Carestream Health, Inc.
Ductal Carcinoma In Situ, Invasive Breast Cancer
Digital Breast Tomosynthesis Versus Contrast Enhanced Magnetic Resonance Imaging (MRI) for Breast Cancer Staging
The primary objective of this study is to compare the diagnostic accuracy of Digital Breast Tomosynthesis (DBT) versus that of Contrast Enhanced Magnetic Resonance Imaging (CEMRI) in determining the size of breast cancer…
- Trial name
- NCT01060085
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Breast Cancer
Comparison of Digital Breast Tomosynthesis to Conventional Mammography
In March 2009, Health Canada approved Tomosynthesis for use in screening and diagnosis of breast cancer. The Tomosynthesis technology is designed as a complementary imaging model that is incorporated into the 2D Mammography…
- Trial name
- NCT03442478
- Testing
- 2D/3D Tomosynthesis
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Breast Cancer
Test of Digital Breast Tomosynthesis vs. Regular Mammography in Detecting Breast Cancer in Women Undergoing Diagnostic Mammography
Comparison of the ability of DBT and FFDM to detect breast cancer.
- Trial name
- NCT00535327
- Volunteers
- 220 people
- Sponsor
- GE Healthcare
Lung Cancer
Lung Cancer Early Diagnosis With Digital Tomosynthesis: Re-evaluation of Lung Nodule Detection Rate at 5 Years
Lung cancer is the leading cause of cancer-related death around the world, it represents 13% of all new cancer diagnoses. The lung cancer incidence is gradually increasing, especially among women and young people, but the…
- Trial name
- SOS2 (NCT03645018)
- Testing
- diagnosis with tomosynthesis
- Where
- Italy
- Volunteers
- 1,341 people
- Sponsor
- Ospedale Santa Croce-Carle Cuneo
Breast Neoplasms
Digital Breast Tomosynthesis Versus Digital Mammography: A National Multicenter Trial
The goal of this study is to determine the value of the new mammography technique called Digital Breast Tomosynthesis (DBT) compared to the current standard technique Digital Mammography for the early detection of Breast Cancer.
- Trial name
- NCT01524029
- Where
- 5 sites in Austria
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Image Correction
A Case Collection Study for Digital Breast Tomosynthesis (DBT) Using the Senographe Essential
Collect clinical images requested by FDA with GE Breast Tomosynthesis to show they are of acceptable quality as defined in the relevant FDA guidance document before and after artifact correction and in standard screening images.
- Trial name
- NCT01885143
- Testing
- Digital Breast Tomosynthesis
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- GE Healthcare
Breast Cancer
Efficacy of Digital Breast Tomosynthesis + Standard 2- Dimensional Mammography in Breast Cancer
The purpose of this study is to determine if a 3-dimensional mammogram (DBT) may provide additional information to evaluate the extent of disease and additional findings that would aid in staging a new breast cancer patient.
- Trial name
- NCT03190083
- Testing
- 2-dimensional mammogram, digital breast tomosynthesis (DBT)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Automated Breast Ultrasound and Digital Breast Tomosynthesis Screening Compared to Full Field Digital Mammography in Women With Dense Breasts
This study is investigating whether automated whole breast ultrasound can improve detection of cancer in breast cancer screening when used as a supplement to mammography or as a supplement to digital breast tomosynthesis
- Trial name
- NCT02042456
- Testing
- Digital Breast Tomosynthesis, Automated Whole Breast Ultrasound, Full Field Digital Mammography
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Breast Cancer
Pilot Mammography Reader Study to Assess Breast Cancer Detection in FFDM Plus DBT Versus FFDM Alone
The purpose of this pilot is to provide credible performance estimate information in order to conduct subsequent reader studies.
- Trial name
- NCT02511730
- Testing
- FFDM Plus DBT, FFDM
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Breast Neoplasms
The Tomosynthesis Trial in Bergen - Part 2
The aim of the study is to compare early performance measures and economic aspects of organized breast cancer screening for women screened using digital breast tomosynthesis+synthetic mammography (DBT+SM) to women with a prior…
- Trial name
- To-Be 2 (NCT03669926)
- Testing
- Digital Breast Tomosynthesis+synthetic mammography
- Where
- Norway
- Volunteers
- 31,082 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Distal Radius Fracture, Scaphoid Fracture
Use of Digital Tomosynthesis for Detection and Case Management of Scaphoid and Distal Radius Fractures: A VolumeRAD Data Collection Study
The study described herein is being conducted to collect clinical data associated with diagnosis and treatment information using the VolumeRAD advanced application.
- Trial name
- NCT03856450
- Testing
- DTS, X-ray, MRI or CT
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Breast Abnormalities
Assessment of Digital Breast Tomosynthesis (DBT) in the Screening Environment
The objective of this study is to demonstrate that digital breast tomosynthesis (DBT) in combination with full field digital mammography (FFDM) has the potential to reduce significantly baseline screening recall rates without a…
- Trial name
- NCT01106911
- Testing
- tomosynthesis and screening mammography
- Where
- United States
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Wrist Injury, Tibial Fracture
Pilot Study Comparing Diagnostic Imaging Versus Tomosynthesis in Detection of Hip, Wrist or Tibia Injury
To acquire and build a library of image sets to determine if Fuji's TOMO imaging device can replace or compliment current imaging standards to assess patients with hip, wrist or tibia injuries.
- Conditions
- Wrist Injury, Tibial Fracture, Hip Injury
- Trial name
- TOMO (NCT01927575)
- Testing
- Standard X-Ray + CT, Standard X-Ray + MRI, TOMO
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Breast Cancer Screening
Digital Breast Tomosynthesis for the Dutch National Breast Cancer Screening Program
Digital breast tomosynthesis (DBT) creates a digital pseudo- three-dimensional image of the breast similar to mammography. This gives the screening radiologist more information about a possible abnormality.
- Trial name
- STREAM (NCT06059300)
- Testing
- Digital Breast Tomosynthesis
- Where
- Netherlands
- Volunteers
- 18,200 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Breast Cancer
Digital Breast Tomosynthesis Guided Tomographic Optical Breast Imaging (TOBI)
Screening for breast cancer improves early detection of aggressive cancers and has been shown to reduce breast cancer related mortality.
- Trial name
- NCT02033486
- Testing
- TOBI + DBT
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Screening
Clinical Utility of Whole Breast Screening Ultrasound in Patients Undergoing Digital Breast Tomosynthesis
The purpose of this study is to determine whether ultrasound or Digital breast tomosynthesis (DBT) detects more cancers and to compare the types of cancers detected on ultrasound and DBT.
- Trial name
- NCT02174406
- Testing
- breast ultrasound, DBT (Full field digital mammography + tomosynthesis)
- Where
- United States
- Volunteers
- 1,494 people
- Sponsor
- Memorial Sloan Kettering Cancer Center