Clinical trials: Dilutional Coagulopathy
Perioperative Hemorrhage, Dilutional Coagulopathy
Impact of Balanced Crystalloid and Colloid Infusion on Haemostasis in Healthy Male Volunteers
The project focuses on perioperative bleeding that requires transfusion of blood products and supplementation of intravascular volume with crystalloids and colloids.
- Trial name
- NCT05148650
- Testing
- Standard laboratory coagulation tests and rotational thromboelastometry measurements
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Congenital Heart Defects
Autologous Fresh Whole Blood and Coagulation Following Cardiopulmonary Bypass in Infants
Dilution of blood caused by cardiopulmonary bypass (the heart-lung machine) during open heart surgery is associated with decreased concentrations in the blood of coagulation factors.
- Trial name
- NCT00006186
- Testing
- Autologous fresh whole blood
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Blood Coagulation Disorders, Hemorrhage
Fibrinogen for Treatment of Pediatric Dilutional Coagulopathy. FibPaed Study.
The purpose of this study is to compare two different thromboelastometry (ROTEM) trigger levels for administration of human fibrinogen concentrate (Haemocomplettan P) in the treatment of perioperative dilutional coagulopathy…
- Trial name
- NCT01487837
- Testing
- Human fibrinogen concentrate
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- University Children's Hospital, Zurich
Dilutional Coagulopathy
Hemodilution and Coagulopathy With 3 Colloids
Aim of this in vitro trial is to assess the effect on blood coagulation after 60 % dilution with different colloids (HES 130/0.42, Gelatin and Gelatin balanced) and investigate reversibility by replacement of fibrinogen (FBG)…
- Trial name
- NCT01727830
- Testing
- Induced Coagulopathy by HES (Tetraspan), Gelatin (Physiogel), Gelatin balanced (Physiogel balanced)
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Blood Coagulation Disorder
Dilutional Coagulopathy in Patients Undergoing Elective Surgery
The purpose of the present study is to perform a comprehensive description of haemostasis parameters before and after haemodilution with Hydroxyethyl starch (HES) following acute bleeding during elective surgery.
- Trial name
- NCT00493272
- Testing
- Fibrinogen
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Christian Fenger-Eriksen