Clinical trials: Diminished Ovarian Reserve
Infertility
Growth Hormone to Improve the Clinical Outcome of Assisted Fertility in Young Patients With Decreased Ovarian Reserve
This study was a prospective randomized controlled trial. Patients aged <35 years with decreased clinical reserve function (AFC<5, Follicle stimulating hormone > 10miu/ml, Anti-mullerian hormone < 1.1μg/L) and receiving IVF/ICSI…
- Trial name
- NCT05585177
- Testing
- Growth hormone
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Nanjing University
Diminished Ovarian Reserve (DOR)
Multi-Site Cortical Puncture for DOR
A multicenter, prospective, randomized controlled clinical trial. The target population consists of patients undergoing IVF/ICSI artificial reproduction who plan to undergo ovarian stimulation and embryo retrieval (DOR) within 4…
- Trial name
- MSCPD (NCT07568639)
- Testing
- multiple ovarian cortex punctures, routine oocyte retrieval procedure
- Where
- 7 sites in China
- Volunteers
- 214 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Ovarian Reserve, Acupuncture Therapy
Clinical Efficacy of Acupuncture on the Liver Meridian in Women With Diminished Ovarian Reserve
Diminished ovarian reserve (DOR) refers to a decrease in the number and quality of oocytes in the ovary, which results in impaired ovarian function and decreased fertility.
- Conditions
- Ovarian Reserve, Acupuncture Therapy, Meridian
- Trial name
- GJZLLCCBGNXJ (NCT05743218)
- Testing
- electropuncture
- Where
- China
- Volunteers
- 198 people
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Diminished Ovarian Reserve (DOR)
Testing Herbal Pretreatment For IVF Success In Women With Low Ovarian Reserve
The goal of this clinical trial is to learn if a traditional Chinese herbal pretreatment can improve pregnancy outcomes in infertile women with diminished ovarian reserve (DOR) who are undergoing in vitro fertilization (IVF) or…
- Trial name
- PRIME (NCT07347340)
- Testing
- Bushen Tongzhi Formula
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Peking Union Medical College Hospital
Diminished Ovarian Reserve
Study of Acupoints in Diminished Ovarian Reserve Based on Biological Characteristics
Diminished Ovarian Reserve (DOR) is characterized by decreased female fertility, menstrual disorders and perimenopausal symptoms due to sex hormone deficiency or fluctuations.
- Trial name
- NCT06395623
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xiaomei Shao
Diminished Ovarian Reserve
Efficacy of Thumb-tack Needle Treatment for Diminished Ovarian Reserve
Diminished Ovarian Reserve (DOR) is characterized as an important cause of infertility. Acupuncture has been extensively used to treat female infertility.
- Trial name
- NCT06223178
- Testing
- thumb-tack needle, Basic gynecological treatment
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Xiaomei Shao
Diminished Ovarian Reserve
Effect of Thumbtack Needle (TN) on Ovarian Reserve Function of Women With Diminished Ovarian Reserve (DOR)
Using a multi-center, large sample, randomized, patient-assessor blinded, sham-controlled clinical trial to evaluate the effect of thumbtack needle (TN) on ovarian function of patients with diminished ovarian reserve (DOR).
- Trial name
- TN-DOR (NCT05277948)
- Testing
- active TN and ETN treatment
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Dongmei Huang
POSEIDON Category 4, Low Prognosis in Assisted Reproductive Technology
Impact of Day 2 Versus Day 3 Fresh Embryo Transfer on Live Birth Rate in Poor-Prognosis Patients
This study aimed to compare the efficacy (live birth rate) of fresh embryo transfer on Day 2 versus Day 3 in POSEIDON Group 4 patients, and to determine the optimal timing of embryo transfer for this population.
- Conditions
- POSEIDON Category 4, Low Prognosis in Assisted Reproductive Technology, Female Infertility Due to Diminished Ovarian Reserve
- Trial name
- NCT07533695
- Testing
- Day 2 Fresh Embryo Transfer
- Volunteers
- 470 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Premature Ovarian Failure, Diminished Ovarian Reserve
Effects of Intraovarian Platelet Rich Plasma in Women With Poor Ovarian Response and Premature Ovarian Insufficiency
Reproductive age women diagnosed with poor ovarian response (POR) based on Poseidon criteria and premature ovarian insufficiency (POI) based on ESHRE criteria and with a history of at least one prior failed IVF cycle will be…
- Trial name
- NCT04237909
- Testing
- PRP injection into at least one ovary
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Acibadem University
Diminished Ovarian Reserve (DOR), Thin Endometrium
A Randomized Controlled Study on the Effect of MRJPs on Improving Ovarian Function and Endometrial Receptivity
This study will assess the effects of the rose tablet candies produced by MRJPs on the subjects, evaluate the role of MRJPs in the ovarian function and endometrial receptivity of women, reveal the potential application value of…
- Trial name
- NCT07246733
- Testing
- Oral MRJPs Candy
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Diminished Ovarian Reserve (DOR)
Guishen Yijing Formula for Diminished Ovarian Reserve: A Real-World Retrospective Study
The goal of this observational study is to learn about the real-world effectiveness of Guishen Yijing Formula in women with diminished ovarian reserve (DOR).
- Trial name
- GSYJ;DOR (NCT07660692)
- Testing
- Guishen Yijing Formula(Chinese herbal decoction)
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Shi Yun
Female Infertility Due to Diminished Ovarian Reserve, Menopausal Syndrome
Cohort Study to Evaluate Ovarian Function
The study will collect the clinical and biological data of the patients, the investigators could further analyse and identify the risk factors and optimize clinical treatment method.
- Conditions
- Female Infertility Due to Diminished Ovarian Reserve, Menopausal Syndrome, Sexual Function and Fertility Disorders, Cardiovascular Diseases
- Trial name
- NCT02294500
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Shixuan Wang
Diminished Ovarian Reserve
The Effeciency of NMN in Improving IVF/ICSI-ET Pregnancy Outcomes in Patients With DOR
The purpose of the study is to understand the effect of nicotinamide mononucleotide (NMN) on patients with diminished ovarian reserve and the outcomes of IVF/ICSI-ET.
- Trial name
- NCT06426355
- Testing
- NMN
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Disorder of Phosphate, Calcium and Vitamin D Metabolism, Female Infertility Due to Diminished Ovarian Reserve
Vitamin D Influence on Oocyte Donation
Objective: To investigate the correlation between total and bioavailable serum 25-OH vitamin D, ovarian reserve and ovarian response to controlled stimulation in egg donors.
- Conditions
- Disorder of Phosphate, Calcium and Vitamin D Metabolism, Female Infertility Due to Diminished Ovarian Reserve, Hormonal Requirement, Reproductive Disorder
- Trial name
- NCT02341365
- Testing
- vitamin D,AMH, AFC, reproductive outcome egg recipients
- Volunteers
- 269 people
- Sponsor
- IVI Madrid
Diminished Ovarian Response
Transplantation of hAMSCs for Woman With DOR
Patients with Diminished ovarian response (DOR）have a poor in vitro fertilization（IVF） outcome, and is considered one of most challenging tasks in artificial reproductive treatment (ART).
- Trial name
- NCT04706312
- Testing
- stem cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Infertility
Dehydroepiandrosterone (DHEA)Supplementation Pre-IVF(In Vitro Fertilization) Cycles
The purpose of this study is to compare the effect of pre-IVF cycles treatment with and without DHEA(Dehydroepiandrosterone) on the ovarian reserve markers, the number of oocytes obtained and IVF(in vitro fertilization) outcomes…
- Trial name
- IVF (NCT02866253)
- Testing
- DHEA
- Volunteers
- 78 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
IVF
Platelet Rich Plasma on Ovarian Reserve Parameters and Intra Cytoplasmic Sperm Injection Outcomes in Patients With Diminished Ovarian Reserve
The aim of this study is to evaluate the efficacy of intra ovarian injection of autologous platelet rich plasma on ovarian reserve parameters and ICSI outcomes in poor ovarian reserve.
- Trial name
- NCT06048666
- Testing
- Intra ovarian by platelet rich plasma
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Beni-Suef University
Poor Ovarian Reserve, Infertility (IVF Patients)
Drospirenone-Primed Ovarian Stimulation Versus GnRH Antagonist Protocol in Poor Ovarian Responders Undergoing Freeze-All IVF/ICSI
Participants will: Take either drospirenone (a daily pill) or the standard daily injection during their ovarian stimulation cycle, alongside their regular fertility hormone injections Undergo egg retrieval, with all resulting…
- Trial name
- PPOS (NCT07736261)
- Testing
- Drospirenone drug, Cetrorelix 0.25 mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahmed Saad
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Female Infertility Due to Diminished Ovarian Reserve, Vitamin D Deficiency
Differences in Ovarian Reserve Markers and Vitamin D Between Infertile Indian, Arabian and Caucasian Population
The aim of this study is to confirm the difference in ovarian reserve markers and serum vitamine D levels between infertile indian, arabian and caucasian population.
- Conditions
- Female Infertility Due to Diminished Ovarian Reserve, Vitamin D Deficiency, Hormone Deficiency, Follicular Cyst of Ovary
- Trial name
- NCT02209168
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- IVI Madrid