Clinical trials: Diplegia, Spastic
Major Depressive Disorder
IM and IV SPL026 Drug Product in Healthy Participants
The goal of this clinical trial is to test SPL026 given via injection into a muscle in healthy volunteers.
- Trial name
- NCT05644093
- Testing
- SPL026 IV, SPL026 IM
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Small Pharma Ltd
Trigger Finger, Trigger Thumb
Trigger Finger Preference Elicitation Tool
The purpose of this study is to evaluate a patient's level of decisional conflict for their treatment decision regarding their trigger finger, and study if the use of a preference elicitation tool at point of care is able to…
- Conditions
- Trigger Finger, Trigger Thumb, Trigger Digit, Trigger Finger Disorder
- Trial name
- NCT03909490
- Testing
- Preference elicitation tool, handout
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Cigarillo Flavor
Attitudes and Perceptions Attitudes and Smoking Perceptions in the Real Environment -II
This multi-method project will recruit young adults who currently use cigarillos and examine the effects of different flavored cigarillo types (concept, characterizing, tobacco) on three measures of tobacco product appeal…
- Trial name
- ASPIRE-II (NCT06668350)
- Testing
- Smoking outcomes
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Spastic Diplegia Cerebral Palsy
Loaded and Task Specific Training in Spastic Diaplegic CP to Improve Gait and Functional Mobility.
Cerebral Palsy is a non-progressive condition caused by early brain injury that affects movement, posture, and muscle tone. Spastic diplegia mainly involves the lower limbs, leading to stiffness, weakness, and abnormal gait…
- Trial name
- ELTTS-GFM-SDCP (NCT07474818)
- Testing
- Loaded Treadmill Training, Task specific Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Cerebral Palsy, Spastic Diplegia
Pelvic Alignment in Relation to Standing Balance and Selective Motor Control in Children With Spastic Diplegia
This study will be conducted to identify the relation between pelvic alignment and standing balance and also the relation between pelvic alignment and selective motor control in children with spastic diplegic cerebral palsy.
- Trial name
- NCT05014451
- Volunteers
- 40 people
- Sponsor
- Cairo University
Diplegic Spastic Cerebral Palsy
Comparing the Instrument-Assisted Soft Tissue Mobilization and Neurodevelopmental Therapy for Gross Motor Functions, Muscle Tone and Spasticity in Children with Spastic Diplegic Cerebral Palsy (GMFCS Levels I and II)
Cerebral palsy is a neurological condition that affects individuals worldwide, with a global burden of 0.9%. However, prevalence rates show regional variation, with high-income countries reporting rates of 0.2% and low-income…
- Trial name
- IASTM;NDT;CP (NCT06702709)
- Testing
- Instrument Assisted Soft Tissue Mobilization, Neurodevelopmental Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Ziauddin University
Cerebral Palsy Spastic Diplegia
Effect of Electrical Stimulation With Functional Task Training on Balance and Motor Abilities in Children With Diplegia
The aims of the study are to: 1. Investigate the combined effect of functional task training with electrical stimulation of bilateral hip abductor muscles on balance in children with diplegia. 2.
- Trial name
- NCT06234215
- Testing
- functional electrical stimulation, functional task training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy Spastic Diplegia
Effects of Dynamic Surface Exercise Training on Trunk Control and Gross Motor Functions in Children With Diplegic Cerebral Palsy
The purpose of this study was to determine the effect of dynamic surface exercise treatment on trunk control and gross motor abilities in children with spastic diplegic cerebral palsy.
- Trial name
- NCT05946096
- Testing
- Dynamic surface exercise training, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Ayesha Hameed
Cerebral Palsy
Distal Rectus Femoris Transfer as a Part of Multilevel Surgery in Children With Spastic Diplegia
The purpose of this study is to evaluate the effects of an additional distal rectus femoris transfer carried out as a part of single-event multilevel surgery in children with spastic diplegic cerebral palsy.
- Trial name
- RectusTrans (NCT01381198)
- Testing
- Distal rectus femoris transfer
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Heidelberg University
Cerebral Palsy
Task Oriented Activities Based on NDT Therapy Principles
Cerebral palsy (CP) is one of the primary causes of disability effecting majority of pediatric population. Cerebral Palsy is considered a neurological disorder caused by a non-progressive brain injury or malformation that occurs…
- Trial name
- NCT05903729
- Testing
- Neurodevelopmental therapy treatment, conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Cerebral Palsy Spastic Diplegia
Comparison of the Effects of Vojta and Bobath Treatment on Gait and Balance in Diplegic Cerebral Palsy
This study aims compare the effects of Vojta verses Bobath therapy on gait in children with diplegic cerebral palsy and to compare the effects of Vojta versus Bobath therapy on balance in children with diplegic cerebral palsy.
- Trial name
- NCT06757101
- Testing
- Vojta Therapy, Bobath Therapy, Combined Vojta and Bobath Therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Riphah International University
ADHD
Little Flower Yoga for Kids: Evaluation of a Yoga and Mindfulness Program for Children With Increased Levels of Emotion Dysregulation and Inattention
An initial evaluation of Little Flower Yoga for Kids will be conducted in a small sample of 18-30 Kindergarten and First Grade students (3-5 per class) enrolled in Girls Preparatory Charter School of the Bronx.
- Trial name
- NCT02829528
- Testing
- Little Flower Yoga For Kids
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York University
Cerebral Palsy
Transcranial Direct Current Stimulation Versus Virtual Reality on Gait in Children With Spastic Diplegia
Spastic diplegia is the most frequent type of cerebral palsy (CP), and impaired gait is a common sequela of this condition. The investigators compared the effects of two novel research interventions transcranial direct current…
- Trial name
- NCT05670522
- Testing
- Transcranial direct current stimulation, Virtual reality
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Spastic Diplegic Cerebral Palsy
Strength Training Using Neuromuscular Electrical Stimulation For Children With Cerebral Palsy
The purpose of this study is to determine if using high-intensity, short-duration, intermittent neuromuscular electrical stimulation (NMES) is better than volitional exercise in increasing quadriceps femoris and triceps surae…
- Trial name
- NCT00356343
- Testing
- NMES Strength Training, Volitional Strength Training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diplegic Cerebral Palsy
Balance Training With TENS for Spastic Diplegic Cerebral Palsy
Children with spastic diplegic Cerebral Palsy (CP) often show motor impairment due to a number of deficits; including poor muscle control, weakness, spasticity and reduced range of motion in the extremities.
- Trial name
- NCT06424990
- Testing
- balance training with TENS
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Diplegia, Spastic
The Effect of Fine Motor Skills Training Through Telerehabilitation in Children With Diplegic Cerebral Palsy
The aim of this study is to compare the effect of occupational therapy intervention through two-way video call, versus occupational therapy home program in written form; on handwriting skills, occupational performance, fine motor…
- Trial name
- NCT05169294
- Testing
- Telerehabilitation Program, Written Home Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ekin Akpınar
Bladder Cancer, Colorectal Cancer
The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)
The goal of this study is to understand factors which may influence risk for colorectal and other cancers in families. These factors include genetic variability, in combination with diet and lifestyle.
- Conditions
- Bladder Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer
- Trial name
- NCT01447199
- Testing
- Health and Diet Questionnaire
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Fetal Growth Retardation
Study Aimed At Improving Height With Genotonorm In Children Born Little And/Or Light With Growth Retardation At The Age
To estimate the percentage of children with serum IGF-1 > 2 standard deviation (compared to a child of the same gender and age and without growth hormone (GH) deficiency) 9 months and 12 months after initiation of GH treatment.
- Trial name
- NCT00174252
- Testing
- Genotonorm (Somatropin)
- Where
- 22 sites in France
- Volunteers
- 57 people
- Sponsor
- Pfizer
Acute Pain, Procedural Anxiety
Little NIRVANA for Pediatric Pain and Anxiety
The aim of this study is to test the feasibility of using Little NIRVANA (augmented reality (AR)) for managing anxiety and pain for children 2-8 years old during hospital emergency peripheral intravenous (PIV) insertions.
- Conditions
- Acute Pain, Procedural Anxiety, Pediatric ALL, Emergency Medicine
- Trial name
- NCT06795126
- Testing
- Little NIRVANA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Nationwide Children's Hospital
Diplegia, Spastic
Eye-Hand Coordination in Children With Spastic Diplegia
This study will examine how the brain controls eye-hand coordination (visuomotor skills) in children with spastic diplegia and will determine whether impairment of this skill is related to the learning difficulties in school that…
- Trial name
- NCT00024791
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)