Clinical trials: Disabilities Physical, open to volunteers
Disability
A Digitally-Enabled System for Precision Assessment and Intervention of Disability Risk in Older Adults
1. Identify the primary risk factors for disability in older adults through multi-dimensional risk factor screening. 2. Develop a risk stratification model for disability in older adults by integrating outcome indicators and…
- Trial name
- NCT07508813
- Testing
- Risk Assessment of Disability and Precision Intervention
- Where
- China
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Preterm Birth, Developmental Dyslexia
Reading-FREE Markers for Early Detection of Developmental Dyslexia
This study aims to identify early signs of developmental dyslexia (DD) and other reading difficulties in children born preterm, using behavioral, cognitive, and brain imaging data collected before reading problems typically…
- Trial name
- FREE-DD (NCT07072104)
- Testing
- Multidomain Neuropsychological and Reading-Free Screening Tool (RSFT) Assessment Battery - Grade 2, MRI - Grade 2, Multidomain Neuropsychological and Reading-Free Screening Tool (RSFT) Assessment Battery - Grade 3
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Physical Activity, Intellectual Disabilities
Advancing Cardiovascular Health Among Adolescents With Intellectual Disabilities: Co-Development of Technology Interventions to Enhance Physical Activity
Adolescents with intellectual disabilities (ID) face significant health issues, particularly in managing chronic conditions such as cardiovascular (CV) health risks.
- Conditions
- Physical Activity, Intellectual Disabilities, Cardiovascular Health
- Trial name
- NCT07919171
- Testing
- Virtual reality physical activity health promotion intervention
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Social Isolation in Older Adults, Social Isolation or Loneliness
CAPABLE Care + Connect
In this evaluation scale-up research project, the investigators seek to test an implementation of CAPABLE on the infrastructure of home-based primary care for individuals who may experience social isolation and/or loneliness.
- Conditions
- Social Isolation in Older Adults, Social Isolation or Loneliness, Social Isolation, Quality of Life
- Trial name
- NCT07123298
- Testing
- CAPABLE Care + Connect - Open Label Pilot, CAPABLE Care + Connect - Pilot
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Intellectual Disability, Neurodevelopmental Disorders
Physical Activity and Community EmPOWERment Project
Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease…
- Conditions
- Intellectual Disability, Neurodevelopmental Disorders, Autism Spectrum Disorder, Down Syndrome
- Trial name
- PACE (NCT06740162)
- Testing
- PACE Program
- Where
- 2 sites in United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Diet Habits, Body Composition
Body Composition and Lifestyles in Athletes With Disabilities
Disability involves limitations that affect mobility and the ability to perform daily activities and achieve competitive goals. It is expected that disability has a significant impact on body composition, including reductions in…
- Conditions
- Diet Habits, Body Composition, Athlete Assessment, Sport Nutrition
- Trial name
- PADES (NCT07464899)
- Testing
- Diet, body composition, Physical activity
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Obesity Prevention, Pediatric Obesity
Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adolescents With Trisomy 21: LiverTy Project
Childhood obesity is a growing public health issue affecting millions of children worldwide, increasing the risk of metabolic and cardiovascular diseases in adulthood.
- Conditions
- Obesity Prevention, Pediatric Obesity, Trisomy 21, Down Syndrome (Trisomy 21)
- Trial name
- LiverTy (NCT06888570)
- Testing
- To evaluate fat liver content in the cases/controls population.
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Amputation, Functional Limitation
Impact Evaluation of Breizh Fabribus Intervention for Personalized Assistive Technology Creation or Adaptation
In France, more than 14 million individuals report severe functional limitations, and nearly 5 million struggle with essential daily activities.
- Conditions
- Amputation, Functional Limitation, Autonomy of Older People, Handicaps Physical
- Trial name
- BFB-IMPACT (NCT07314099)
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fondation Ildys
Disability Physical, Disabilities Mental
Technology in Play for Children With Physical Disabilities: the Dice Model of Play
Play is an important activity for children. Almost all children play, but what is play? It is not easy to define play. In the past, people believed that children played to burn their energy.
- Trial name
- NCT06319430
- Testing
- robots, conventional
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Multiple Sclerosis
Early Symptoms in Multiple Sclerosis: an Investigation Using fMRI and Gait Analysis to Develop Personalized Balance Training for People With Low Disability
Background Many people with Multiple Sclerosis (MS) experience a hidden yet clinically significant symptom: impaired balance or a persistent feeling of instability, even during the early stages of the disease (Martin et al.…
- Trial name
- EMS_Rehab (NCT07805733)
- Testing
- Vestibular Physical Therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LIFE - Research and Care Institute - Santa Lucia IRCCS
Children, Neurologic Disorder
Psychometric Properties of the Turkish Version of the Modified Mini Mental State Examination
One of the most commonly used screening tests for the mental status of adults is the Standardized Mini Mental State Examination (MMSE).
- Conditions
- Children, Neurologic Disorder, Cerebral Palsy, Down Syndrome
- Trial name
- NCT06865248
- Where
- Cyprus
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Episodic Migraine, Chronic Migraine
CGRP Inhibition, Autonomic Function, and Migraine
The purpose of this clinical study is to better understand the function of the autonomic nervous system in patients with migraine. We aim to understand whether the autonomic functions change depending on the migraine status (i.e.
- Trial name
- CGRP-1 (NCT04628429)
- Testing
- Erenumab, Galcanezumab, Fremanezumab
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Multiple Sclerosis, Healthy Adults
Gait Adaptability in Persons With MS Having Mild Disability
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system that frequently leads to walking impairment, balance deficits, fatigue, cognitive difficulties, and an increased risk…
- Trial name
- NCT07580820
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Type 2 Diabetes (T2DM), Geriatric Syndromes
Using Virtual Reality to Improve Medical Training
As the U.S. population ages, future physicians must be prepared to care for older adults with multiple health conditions and complex needs.
- Conditions
- Type 2 Diabetes (T2DM), Geriatric Syndromes, Disability Hearing, Disability Physical
- Trial name
- NCT07542834
- Testing
- Cinematic Virtual Reality Training, Traditional Didactic Lecture
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ohio University
Down Syndrome
Physical Fitness in DS: A Comparison of Cuevas Medak and Rebound Exercises
This randomized clinical trial investigates the comparative effects of Cuevas Medak Exercises Vs Rebound Exercises on physical fitness in DS.
- Trial name
- DownSyndrome (NCT07248449)
- Testing
- Cuevas Medak Exercises
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Riphah International University