Clinical trials: Disability, Evaluation
Developmental Disability
Interactive Digital Game for Improving Visual Perceptual Defects in Children With Developmental Disability
Visual perceptual defects in children can negatively affect their activities of daily living.The aims of this study were to develop and evaluate an interactive digital game system for correcting visual perceptual defects and to…
- Trial name
- NCT05016492
- Testing
- Visual-perceptual interactive game system, standard rehabilitation
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pain
Clinical Effects of Gelified Ethanol Application in Cervical Disc Hernia
The aim of the study is to evaluate the clinical effects of Discogel® Radiopaque Gelified Ethanol as therapeutic substance for nucleolysis application in the patients with cervical disc hernia who had chronic pain and weakness on…
- Trial name
- NCT02834676
- Testing
- Gelified Ethanol
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Sakarya University
Cerebral Palsy, Spine Deformity
Spine of Caregivers of Children with Cerebral Palsy
The purpose of this study was to assess pain (rest, activity, and night pain using the Visual Analog Scale), disability (neck using the Neck Disability Index; lumbar using the Oswestry Disability Index), and curvature (cervical…
- Trial name
- NCT06443398
- Testing
- There is no intervention in the study
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Williams Beuren Syndrome, Autism Spectrum Disorder
Molecular Characterization of Patients Affected by Williams Syndrome and Autism.
Williams Beuren syndrome (WBS) is a multiple malformations/intellectual disability (ID) syndrome caused by 7q11.23 microdeletion and clinically characterized by a typical neurocognitive profile including excessive talkativeness…
- Trial name
- WBA (NCT04095585)
- Testing
- chromosomal microarray analysis (CMA) and whole exome sequencing (WES)
- Volunteers
- 6 people
- Sponsor
- Hospices Civils de Lyon
Noncardiac Surgery
Patient-Centred Outcomes and Resource Utilisation After Noncardiac Surgery-D(Eutschland) (PACORUS-D)
The PACORUS-D project aims at 1) quantifying the 30-days and 1-year disability burden (assessed using the 12-item WHODAS 2 [WHO Disability Assessment Schedule] questionnaire) after inhospital noncardiac nonneurosurgical…
- Trial name
- PACORUS-D (NCT04675905)
- Testing
- no intervention (cohort study)
- Volunteers
- 1,200 people
- Sponsor
- PD Dr. med. MSc Giovanna Lurati Buse
Headache, Migraine
Comparison of a Drug and Placebo in the Prevention of Migraine Headaches
The purpose of this study is to determine whether ethosuximide works better than placebo in the prevention of episodic migraine among veterans.
- Trial name
- NCT01122381
- Testing
- ethosuximide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- US Department of Veterans Affairs
Spinal Fracture, Osteoporosis
Quality of Life After Vertebroplasty Versus Conservative Treatment in Patients With Painful Osteoporotic Vertebral Fractures
The purpose of this study is to determine whether percutaneous vertebroplasty is able to improve long-term quality of life in patients with pain secondary to osteoporotic vertebral fractures, compared to conventional medical…
- Conditions
- Spinal Fracture, Osteoporosis, Back Pain
- Trial name
- NCT00994032
- Testing
- percutaneous injection of cement into the vertebral body, Medical treatment
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital Clinic of Barcelona
Fragile X Syndrome
Long-term, Safety, Tolerability and Efficacy Study of AFQ056 in Adult Patients With Fragile X Syndrome
The purpose of this study is to generate long-term safety, tolerability and efficacy data for AFQ056 in eligible adult patients with FXS who have participated in the CAFQ056A2212 (NCT01253629).study and patients who have…
- Trial name
- NCT01348087
- Testing
- AFQ056
- Where
- 28 sites in United States, Australia and 8 more
- Volunteers
- 148 people
- Sponsor
- Novartis Pharmaceuticals
Disability
A Digitally-Enabled System for Precision Assessment and Intervention of Disability Risk in Older Adults
1. Identify the primary risk factors for disability in older adults through multi-dimensional risk factor screening. 2. Develop a risk stratification model for disability in older adults by integrating outcome indicators and…
- Trial name
- NCT07508813
- Testing
- Risk Assessment of Disability and Precision Intervention
- Where
- China
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Epilepsy, Insomnia
Trial of Melatonin to Improve Sleep in Children With Epilepsy and Neurodevelopmental Disabilities
The purpose of the study is to evaluate the safety and efficacy of oral melatonin in improving sleep continuity in children with epilepsy and neurodevelopmental delay who have chronic insomnia by comparing Fast Release Melatonin…
- Conditions
- Epilepsy, Insomnia, Developmental Disability
- Trial name
- NCT01161108
- Testing
- Fast Release Melatonin (FR MLT), Timed Release Melatonin (TR MLT)
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- The Hospital for Sick Children
Down Syndrome, Gross Motor Development Delay
Investigating Trunk Control in Young Children With Down Syndrome
Overall, the purpose of this dissertation research is to investigate trunk control in young children with DS. This will be done in three studies: 1.
- Trial name
- NCT03544840
- Testing
- Physical Therapy Home Program
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Texas Woman's University
Down Syndrome
Evaluation of a Simplified Method for Diagnosis of Sleep Apnea in Children and Adults With Down Syndrome
People with Down syndrome are at increased risk of sleep apnea, not only from obstruction of the upper airway, but also of central origin.
- Trial name
- SAOS/T21 (NCT00951730)
- Testing
- Polysomnography
- Where
- 3 sites in France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Profound Multiple Intellectual Disabilities
Development of a Visio-behavioral Scale to Evaluate Visual Abilities of Patients With Profound Multiple Intellectual Disabilities (PLH-Vision)
The main objective of this study is to develop and validate a visio-behavioral scale of visual abilities for subjects with profound multiple intellectual disabilities.
- Trial name
- PLH-Vision (NCT03040609)
- Testing
- Visual-behavioral Scale at day 1, Test-retest at the end of 2 weeks, Test at 6 months
- Where
- France
- Volunteers
- 232 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sexual and Reproductive Health, Disability
Evaluation of a Disability-Focused Sexual and Reproductive Health Curriculum for Health Students in Tanzania
This randomized controlled trial will evaluate the efficacy of a three-day sexual and reproductive health curriculum focused on persons with disabilities and tailored to the Tanzanian context.
- Conditions
- Sexual and Reproductive Health, Disability, Health Knowledge, Attitudes, Practice, Health Education
- Trial name
- NCT07772778
- Testing
- Disability-Focused Sexual and Reproductive Health Curriculum
- Where
- Tanzania
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Neck Pain, Neck Pain Musculoskeletal
Neck Musculoskeletal Symptoms Among Turkish Endodontists
This observational study aims to evaluate the prevalence, severity, and characteristics of neck musculoskeletal symptoms among Turkish endodontists.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Musculoskeletal Assessment, Musculoskeletal Disorder of the Neck
- Trial name
- ENDO-NECK (NCT07516782)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlas University
Lumbar Disc Herniation
Evaluation of the Effectiveness of Focused Radiofrequency (TECAR) Therapy on Pain, Disability, Function, and Quality of Life in Patients With Lumbar Disc Herniation
Low back pain is a very common health problem in societies, regardless of the underlying cause. Its lifetime prevalence has been reported to be as high as 75-80%.
- Trial name
- TECAR THERAPY (NCT07335718)
- Testing
- TECAR THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Challenging Behaviour
Evaluation of Parent Intervention for Challenging Behaviour in Children With Intellectual Disabilities (EPICC-ID)
Children with intellectual disabilities are likely to present with challenging behaviour. Parent mediated interventions have shown utility in influencing child behaviour, although there is a paucity of UK research into…
- Trial name
- NCT03086876
- Testing
- Level 4 Stepping Stones Triple P (SSTP)
- Where
- 4 sites in United Kingdom
- Volunteers
- 261 people
- Sponsor
- University College, London
Neck Pain, Myofascial Pain Syndrome
ACUTE EFFECT OF DIAPHRAGMATIC BREATHING ON POSTOPERATIVE UPPER TRAPEZIUS PAIN
This randomized controlled trial aims to investigate the acute effects of diaphragmatic breathing exercises added to soft tissue mobilization and percussive therapy on pain intensity, functional disability, and pressure pain…
- Conditions
- Neck Pain, Myofascial Pain Syndrome, Work-Related Musculoskeletal Disorders
- Trial name
- TRAP-BREATHE (NCT07634588)
- Testing
- Diaphragmatic Breathing Exercise, Soft Tissue Mobilization, Percussive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Istanbul Aydın University
Central Sensitisation, Chronic Musculoskeletal Disease
The Frequency of Central Sensitization in Patients With Chronic Musculoskeletal Pain
Central sensitization is as increased response to normal or sub-threshold stimuli of central nervous system and its close relationship with in many musculoskeletal diseases with chronic pain has been demonstrated in several…
- Conditions
- Central Sensitisation, Chronic Musculoskeletal Disease, Chronic Pain
- Trial name
- NCT04765280
- Testing
- Central sensitization inventory, Short form-36, Istanbul Low Back Pain Disability Index
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Marmara University
Down Syndrome, Cognitive Dysfunction
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10
The purpose of this study is to determine the efficacy and safety of donepezil hydrochloride (Aricept) in the treatment of cognitive dysfunction shown by children with Down syndrome, aged 6 to 10 years.
- Trial name
- NCT00754013
- Testing
- Aricept (Donepezil hydrochloride)
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Eisai Inc.