Clinical trials: Disability, Evaluation
Down Syndrome, Amyloid Beta-protein
Phase II Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid.
To determine the sensitivity of the visual assessment of BAY94-9172 PET images in detecting cerebral β-amyloid in individuals with Down Syndrome (DS) and specificity in individuals without DS.
- Trial name
- NCT00928304
- Testing
- Florbetaben (BAY94-9172)
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Lantheus Biosciences Ltd.
Rett Syndrome
Creatine Metabolism in Rett Syndrome
Rett syndrome (RTT) is an X-linked severe neurodevelopmental disorder. Despite their good appetite, many females with RTT meet the criteria for moderate to severe malnutrition. The pathological mechanism is barely understood.
- Trial name
- NCT01198015
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Maastricht University Medical Center
Williams Beuren Syndrome, Autism Spectrum Disorder
Molecular Characterization of Patients Affected by Williams Syndrome and Autism.
Williams Beuren syndrome (WBS) is a multiple malformations/intellectual disability (ID) syndrome caused by 7q11.23 microdeletion and clinically characterized by a typical neurocognitive profile including excessive talkativeness…
- Trial name
- WBA (NCT04095585)
- Testing
- chromosomal microarray analysis (CMA) and whole exome sequencing (WES)
- Volunteers
- 6 people
- Sponsor
- Hospices Civils de Lyon
Meniere Disease, Psychosocial Problem
Comprehensive Evaluation in Patients With Meniere's Disease
The aim of our study is to determine the severity of the disease in people with Meniere's Disease; physical conditions such as balance, posture, pain, physical activity level, neck joint range of motion, proprioception; to…
- Conditions
- Meniere Disease, Psychosocial Problem, Physical Disability, Quality of Life
- Trial name
- NCT05844657
- Testing
- Case report form, Tinnitus disability scale, A feeling of fullness and/or pressure in the ear
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Down Syndrome
Investigation of the Safety of Intranasal Glulisine in Down Syndrome
This study is a single center, randomized, double-blind, placebo-controlled, cross-over pilot study designed to assess the safety of intranasally (IN) delivered glulisine versus placebo in patients with DS.
- Trial name
- NCT02432716
- Testing
- Insulin glulisine, Saline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- HealthPartners Institute
Intellectual Disability
Methylation Pattern and Pain Sensation in Children With Intellectual Disability
Previous literature data indicate that children with intellectual disability (ID) experience more severe pain and more frequently than their cognitively healthy peers, during their daily life.
- Trial name
- NCT06317506
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- IRCCS Burlo Garofolo
Dyslexia
Dyslexics' Visual Attention Field
dyslexia is often considered like a phonological deficit but some researches show that a visual attention (V-A) deficit can occur in dyslexia.
- Trial name
- NCT03285789
- Testing
- Passing tests in dyslexics with reduced eva, Passing tests in controls
- Where
- France
- Volunteers
- 1,460 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Mental Retardation, Body Composition, Beneficial
Resistance Training Program, Labor Inclusion, Intellectual Disability
Resistance exercise (RE) has been proposed as a possible strategy for prevention and rehabilitation of diseases. The increase in both muscle strength and the ability to perform tasks of day-to-day work environment and are…
- Conditions
- Mental Retardation, Body Composition, Beneficial, Muscle Weakness
- Trial name
- NCT01456910
- Testing
- Resistance Training Program
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- University of Brasilia
Low Back Pain, Chronic
Person-Centered Lifestyle Redesign in Chronic Low Back Pain
This study is designed to examine the effects of a person-centered lifestyle intervention on pain, occupational performance, quality of life, disability, physical activity levels, and mental status in individuals with chronic low…
- Trial name
- NCT07163546
- Testing
- Lifestyle intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Shoulder Impingement Syndrome, Subacromial Impingement
The Effect of Mobilization With Movement in Individuals With Shoulder Impingement Syndrome
This study conducted to see the effect of adding mobilization with movement to conventional physical therapy to the subject with shoulder impingement syndrome.
- Conditions
- Shoulder Impingement Syndrome, Subacromial Impingement, Subacromial Impingement Syndrome, Subacromial Pain Syndrome
- Trial name
- SIS (NCT04599127)
- Testing
- Mobilization with movement, Conventional physical therapy
- Where
- Indonesia
- Volunteers
- 22 people
- Sponsor
- Mahidol University
Migraine
Assessment of Head Awareness in Patients With Migraine in the Greek Population
Body perception and awareness may be altered in individuals with chronic pain and may be associated with pain intensity, disability, and pain-related psychological factors.
- Trial name
- NCT07843745
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- National and Kapodistrian University of Athens
Writing Learning Disability
Biomechanical Assessment and Biofeedback-training System for Handwriting
The purpose of this study is to investigate the real-time kinetics of handwriting regarding the design of the utensil and fine motor performances from biomechanical perspectives. It includes three parts.
- Trial name
- NCT03822702
- Testing
- Biofeedback Training, Motor Training
- Where
- Taiwan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Physically Disabled
Advanced Virtual Exercise Environment Device for Use by Persons With Physical Disabilities
An Advanced Virtual Exercise Environment Device (AVEED) has been developed that incorporates arm and leg ergometers in conjunction with a virtual reality interface.
- Trial name
- AVEED (NCT02990507)
- Testing
- AVEED: Arm rotation, video display, AVEED: Arm rotation, without video display, AVEED: Leg rotation, arm-energy input, video display
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Autism Spectrum Disorder, Autism
Dynamic Quantification of Social-Visual Engagement in Autism Spectrum Disorder (ASD)
The goal of this clinical study is to learn about the utility and performance of the EarliPoint System (™): Evaluation for Autism Spectrum Disorder to diagnose and assess autism spectrum disorder (ASD) in children ages 31-96…
- Trial name
- MEASURE-ASD2 (NCT05806216)
- Testing
- EarliPoint Diagnosis, Clinically Certain Expert Clinician Diagnosis (CC-ECD)
- Where
- 9 sites in United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- EarliTec Diagnostics, Inc
Stroke Sequelae, Dependency
Evaluation of Degree of Dependency After Stroke.
Understanding the risk of dependence and its severity before hospital discharge for stroke is important for health and social care planning as instrument to prioritize people where the assistance is more appropriate in a context…
- Trial name
- NCT03451357
- Testing
- Dependence degree already certificated by Dependence Law.
- Where
- Spain
- Volunteers
- 230 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Obstructive Sleep Apnea
Optimizing the Management of OSA in Children With Down Syndrome
The objective of this retrospective descriptive study is to assess current practices for the screening and surgical treatment of OSA in children with Down syndrome at the Strasbourg University Hospital and to disseminate a…
- Trial name
- SAOS-21 (NCT07334444)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Multiple Sclerosis (MS), Telenursing
TELESM-edu.Nursing: a Personalised Nursing Intervention for People With Multiple Sclerosis
The primary aim of this study is to evaluate the impact of the telenursing intervention "TELESM-edu.nursing" on people with Multiple Sclerosis (pwMS), specifically focusing on their navigational capacity within the healthcare…
- Trial name
- TELESM-edu (NCT07640698)
- Testing
- TELESM-edu.nursing, Standard
- Volunteers
- 110 people
- Sponsor
- G. d'Annunzio University
Disability Evaluation
Internet-based Pre-fitting Counseling of Persons With Hearing Impairment
The purpose of this study is to determine whether the use of 'patient journey' model in internet-based counseling of a person with hearing impairment is a feasible approach in management of emotional and social consequences…
- Trial name
- NCT01611129
- Testing
- Internet-based counseling
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 80 people
- Sponsor
- Thomas Lunner
Mucopolysaccharidosis II, Hunter Syndrome
A Study to Evaluate the Safety, Tolerability, PK and PD of Intracerebroventricular GC1123 in Patients with MPS Ⅱ
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of intracerebroventricular GC1123 in patients with MPS Ⅱ who have central nervous system involvement and are receiving…
- Trial name
- NCT05422482
- Testing
- GC1123
- Where
- 3 sites in South Korea
- Volunteers
- 12 people
- Sponsor
- GC Biopharma Corp
Carpal Tunnel Syndrome (CTS)
Effects of Peloid Therapy in Patients With Carpal Tunnel Syndrome
Carpal tunnel syndrome is a common condition caused by pressure on a nerve at the wrist. It can lead to pain, numbness, weakness, and difficulty using the hand during daily activities.
- Trial name
- NCT07417722
- Testing
- Peloid Therapy, Wrist Splint, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital