Clinical trials: Disability, Evaluation
Validation Study
Validation Study of the Italian Version of the "Assessment of Life Habits 4.0" Scale (LIFE-H) for Measuring Participation in Children With Disabilities Aged 5 to 13 Years
BACKGROUNG In Italy there are still few translated and validated instruments to assess participation. In the field of pediatric rehabilitation, among the tools available internationally, one of the most comprehensive and widely…
- Trial name
- NCT06854874
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Meyer Children's Hospital IRCCS
Knee Osteoarthritis
Comparison of Hip Strengthening Exercises and Core Stability Exercises in Patients With Knee Osteoarthritis
Knee Osteoarthritis is a chronic degenerative joint disease with complex etiology that results in loss of normal joint function due to damage to the articular cartilage.
- Trial name
- NCT06120920
- Testing
- Assigned Interventions, Conventional Physical Therapy and Routine Knee Exercises with Hip Strengthening Exercises.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Post -Partum Low Back Pain, Dynamic Neuromuscular Stabilization (DNS)
This Study Aimed to Evaluate the Effect of Dynamic Neuromuscular Stabilization (DNS) on Pain Intensity and Functional Disability in Women With PLBP as Common Problem Affect t he Women After Birth Which Often Impacting Their Quality of Life and Ability to Perform Daily Activities
The aim of this study was to determine the effect of DNS on women with post-partum LBP. Post-partum low back pain (PLBP) represents a prevalent and clinically significant condition that adversely impacts mobility, pelvic floor…
- Conditions
- Post -Partum Low Back Pain, Dynamic Neuromuscular Stabilization (DNS), Women's Health / Physiotherapy, Musculoskeletal Rehabilitation
- Trial name
- NCT07099755
- Testing
- Intervention Group: Name: Dynamic Neuromuscular Stabilization (DNS) Exercises, Control Group:Name: Conventional Physiotherapy (Ultrasound and Infrared Therapy)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gehad Alaa
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Specific Learning Disability, Specific Learning Disorder
HAND FUNCTIONS OF CHILDREN WITH A SPECIFIC LEARNING DISORDER
Children with Specific Learning Difficulties (SLD) may have problems with fine and gross motor skills compared to their healthy peers. These children may have poor manual dexterity.
- Conditions
- Specific Learning Disability, Specific Learning Disorder, Fine Motor Skills, Hand Functions
- Trial name
- NCT05319197
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Multiple Sclerosis
OFSEP Very High Definition Cohort
Multiple sclerosis (MS) is the most common acquired neurological disease leading to disability in young adults. MS often leads to the development of a physical and/or cognitive impairment that disables patients in their daily…
- Trial name
- VHD cohort (NCT05622643)
- Testing
- MRI
- Where
- 5 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- EDMUS Foundation
Mucopolysaccharidosis I, Mucopolysaccharidosis II
Study to Evaluate the Safety and Efficacy of Adalimumab in MPS I, II, and VI
Randomized, double-blind, placebo-controlled, parallel-group, single-center study followed by open-label phase, to evaluate the effects of adalimumab compared to placebo on the change from baseline in joint and skeletal disease…
- Conditions
- Mucopolysaccharidosis I, Mucopolysaccharidosis II, Mucopolysaccharidosis VI
- Trial name
- NCT03153319
- Testing
- Adalimumab Injection [Humira], Saline Solution for Injection
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Cervicogenic Headache
Ischemic Compression Technique Versus Jones Technique in Cervicogenic Headache Patients
The primary objective of the study is to determine the effects of Jones and Ischemic compression technique on pain, range of motion and disability in patients with cervicogenic headache.
- Trial name
- NCT06875869
- Testing
- Jones technique, Ischemic compression therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Prader-Willi Syndrome
A Study of Oral ARD-101 in Patients With Prader-Willi Syndrome
A Phase 2, Single-Arm, Open-Label Study to Evaluate the Safety and Efficacy of ARD-101 in Patients with Prader-Willi Syndrome
- Trial name
- NCT05153434
- Testing
- ARD-101
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Aardvark Therapeutics, Inc.
Neck Pain, Kinesiophobia
Kinesiophobia in Chronic Neck Pain
In this study, the effect of kinesiophobia on pain, disability, and quality of life in individuals with chronic neck pain will be evaluated.
- Trial name
- NCT06849999
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Postpartum Lumbopelvic Pain
Investigation the Effects of Stabilization Exercises on Pain, Disability and Activity of Pelvic Floor Muscles in Patients With Postpartum Lumbopelvic Pain
The purpose of this study was to evaluate the effects of stabilization exercises on pain, disability and pelvic floor muscles function in patients with lumbopelvic pain.
- Trial name
- NCT03030846
- Testing
- Stabilization exercise, Control group
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Preterm Birth, Developmental Dyslexia
Reading-FREE Markers for Early Detection of Developmental Dyslexia
This study aims to identify early signs of developmental dyslexia (DD) and other reading difficulties in children born preterm, using behavioral, cognitive, and brain imaging data collected before reading problems typically…
- Trial name
- FREE-DD (NCT07072104)
- Testing
- Multidomain Neuropsychological and Reading-Free Screening Tool (RSFT) Assessment Battery - Grade 2, MRI - Grade 2, Multidomain Neuropsychological and Reading-Free Screening Tool (RSFT) Assessment Battery - Grade 3
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
COVID-19
Disability Following Hospitalization in People of Working-age Surviving SARS-CoV-2 Infection - COVID-19
The purpose of the study is to describe disability following hospitalization in people of working-age surviving COVID-19.
- Trial name
- DisCOVID (NCT04724395)
- Testing
- Hospitalization
- Where
- France
- Volunteers
- 530 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteo Arthritis Knee, Movement Disorders
Investigation of the Effect of Movement Mobilization Concept on Sensory, Pain, Muscle Activation in Patients With Knee Osteoarthritis
Individuals with knee osteoarthritis are one of the groups most affected by musculoskeletal disorders and experience pain and mobility limitations that significantly limit their daily living activities.
- Conditions
- Osteo Arthritis Knee, Movement Disorders, Physical Disability, Knee Osteoarthritis
- Trial name
- NCT06527313
- Testing
- Movement Mobilization Concept, Exercise and Tape, Special Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istinye University
Abnormalities, Failure to Thrive
Evaluation of Patients With Unresolved Chromosome Abnormalities
The purpose of this research is to study a new way to test for chromosome abnormalities. Chromosomes are strands of DNA (the genetic material in the cell nucleus) that are made up of genes-the units of heredity.
- Conditions
- Abnormalities, Failure to Thrive, Mental Retardation, Microcephaly
- Trial name
- NCT00001639
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Down Syndrome
Oral Language in Children With Down Syndrome
The objective of this research is to verify the language of children with Down syndrome concerning lexical, syntactic and semantic aspects using MLU.
- Trial name
- NCT00952354
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of OP-101 After Intravenous Administration in Healthy Volunteers
A clinical study to measure the effect of OP-101 after being administered intravenously in healthy volunteers.
- Trial name
- NCT03500627
- Testing
- OP-101
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Orpheris, Inc.
Down Syndrome
Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model
This study may provide information that may serve as the foundation for a larger research study to address issues regarding the causes, diagnosis, and treatment of osteoporosis in the Down syndrome patient population.
- Trial name
- NCT01148121
- Testing
- Skeletal Status Assessment of a Down Syndrome Population
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Disability Physical, Disability, Learning
AssessMent and Counseling to Get the Best Efficiency and Effectiveness of the Assistive TeCHnology
The best match between any person with disability and the assistive technology (AT) only can be gotten through a complete assessment and a monitoring of the needs, abilities, priorities, difficult and limitations that he/she…
- Conditions
- Disability Physical, Disability, Learning, Disabling Disease
- Trial name
- MATCH (NCT04723784)
- Testing
- Initial Assessment, Implementation of assistive technology in the daily life of participants, Application of outcome measures
- Where
- 4 sites in Spain
- Volunteers
- 24 people
- Sponsor
- Universidade da Coruña
Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, Including, Sickle Cell Disease
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
Cell-free fetal DNA (cffDNA) is present in the maternal blood from the early first trimester of gestation and makes up 5%-20% of the total circulating cell-free DNA (cfDNA) in maternal plasma.
- Conditions
- Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, Including, Sickle Cell Disease, Cystic Fibrosis, Fragile X Syndrome
- Trial name
- DANNIgene (NCT06147414)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 550 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris