Clinical trials: Disc Herniation
Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation
Multicentric Registry for the Detection of C5 Palsy After Anterior Cervical Discectomy and Fusion
Detect the reason for the frequently occurring C5 palsy after anterior cervical discectomy and fusion
- Conditions
- Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation, Suspected Cervical Spine Instability
- Trial name
- C5registry (NCT02875431)
- Testing
- Patients undergo ACDF or cervical vertebral body replacement
- Where
- Germany
- Volunteers
- 1,087 people
- Sponsor
- Technical University of Munich
Motor Deficits, Lumbar Discectomy
Investigation of Preoperative Factors Influencing the Outcome of Motor Deficits in Patients Undergoing Lumbar Microdiskectomy
Lumbar disc herniations may result in lower limb weakness. In such cases, there is a strong indication for surgical intervention through microdiscectomy.
- Conditions
- Motor Deficits, Lumbar Discectomy, Muscle Weakness, Paresis
- Trial name
- NCT07413302
- Where
- 3 sites in Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Lumbar Disc Herniation
Study of Lumbar Discectomy With Annular Closure
The purpose of this prospective, single-arm, multicenter study is to assess an annular closure device when used as an adjunct to a primary lumbar limited discectomy, to limited discectomy alone.
- Trial name
- NCT03986580
- Testing
- Annular closure device
- Where
- 7 sites in United States
- Volunteers
- 55 people
- Sponsor
- Intrinsic Therapeutics
Giant Thoracic Herniation, Myelopathy
Management of Giant Thoracic Disc Hernias by Thoracoscopy: Experience of 52 Cases
Introduction: Giant thoracic disc herniation is a rare condition for which surgical treatment is indicated when there are signs of spinal cord injury.
- Trial name
- GHTT (NCT03295617)
- Testing
- Thoracoscopy
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Hopital Foch
Lumbal Disc Herniation
A Study Comparing Peloid Therapy and Hot Pack Treatment in Adults With Chronic Low Back Pain Caused by Lumbar Disc Herniation
The goal of this clinical trial is to compare the effectiveness of peloid therapy versus hot pack therapy in adults aged 18-50 with chronic lumbar disc herniation (LDH).
- Trial name
- NCT07087548
- Testing
- Peloid Therapy, Hotpack Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fenerbahce University
Intervertebral Disc Displacement, Sciatica
Outcome of Surgery for Sciatica - a Comparison of Data From Three National Quality Registries
Purpose: The incidence of surgery for lumbar disc hernia varies. According to the national spine registries in Sweden, Norway and Denmark, there is a 30-60% difference in surgical incidence between these countries.
- Trial name
- NCT02889484
- Testing
- Lumbar disc hernia surgery
- Volunteers
- 7,500 people
- Sponsor
- Karolinska Institutet
Low Back Pain, Radiculopathy Lumbar
Efficacy of Transforaminal Epidural Steroid and Its Combination With Ozone in Lumbar Radiculopathy
This retrospective study aimed to assess the clinical effectiveness and safety of transforaminal epidural injections of steroid and ozone mixture versus steroid alone in low back and radicular leg pain related to disk herniation.
- Conditions
- Low Back Pain, Radiculopathy Lumbar, Hernia, Disk Herniated Lumbar
- Trial name
- NCT06503835
- Testing
- Fluoroscopy Guided Transforaminal Epidural Ozone Injection, Fluoroscopy Guided Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ibn Sina Hospital
Central Sensitisation
Investigation of the Relationship Between Central Sensitization and Neuropathic Pain in Lumbar Disc Herniation
Central sensitization (CS) is as increased response to normal or sub-threshold stimuli of central nervous system and its close relationship with in many musculoskeletal diseases with chronic pain has been demonstrated in several…
- Trial name
- NCT06269068
- Testing
- Central sensitization inventory, Short form-36, Oswestry Low Back Pain Disability Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
Lumbar Disc Herniation Surgery, Mechanical Ventilation
Flow-Controlled Versus Volume-Controlled Ventilation in Lumbar Disc Herniation Surgery
This prospective randomized trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in patients undergoing lumbar disc…
- Trial name
- NCT07614555
- Testing
- FCV Group, VCV Group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
To Evaluate the Effect of Exercise With Virtual Glasses on Pain, Activities of Daily Living and Quality of Life
Individuals With Lumbar Disc Hernia Exercising With Virtual Reality Glasses
The purpose of this research; exercise performed with virtual reality glasses for individuals with lumbar disc herniation; The aim of this study is to examine the effects on pain, activities of daily living, quality of life and…
- Trial name
- NCT05463588
- Testing
- Exercising with virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ataturk University
Lumbar Disc Herniation
Remission of Lumbar Disc Herniation by Physiotherapy
This study was conducted with the aim of determining whether or not Non surgical spinal decompression therapy was effective in remission of herniation, decreasing pain and improving functional status.
- Trial name
- NCT02699164
- Testing
- DRX 9000, Axiom Worldwide, Tampa, Florida, physiotherapy, spinal stabilization exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Lumbar Disc Herniation
Brain Effect Mechanism of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI
The clinical symptoms of Lumbar Disc Herniation (LDH) can be effectively ameliorated through Spinal Manipulative Therapy (SMT), which is closely linked to the brain's pain-regulating mechanisms.
- Trial name
- NCT06277739
- Testing
- Spinal Manipulative Therapy
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhou Xingchen
Disk Herniated Lumbar
Safety and Performance of a Hernia Blocking System
Prospective, multi-center, single-arm clinical study to assess the performance of an Hernia Blocking System in preventing clinically symptomatic recurrent lumbar disc herniation.
- Trial name
- NCT04188236
- Testing
- Hernia Blocking System
- Where
- 6 sites in Spain
- Volunteers
- 30 people
- Sponsor
- NEOS Surgery
Lumbar Disc Herniation, Radiculopathy Lumbar
Efficacy and Safety of Electroacupuncture on Lumbar Disc Herniation with Radiculopathy
Lumbar disc herniation with radiculopathy (LDHR) is the local displacement of the intervertebral disc and its contents beyond the edge of the normal intervertebral disc space, resulting in pain, weakness or numbness in the muscle…
- Trial name
- NCT06611332
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Lumbar Disk Herniation
Percutaneous Transforaminal Endoscopic Discectomy vs. Open Microdiscectomy for Lumbar Disc Herniation (PTED-study)
Rationale: Lumbosacral radicular syndrome (LSRS) is caused by a herniated lumbar nucleus pulposus (HNP) and the estimated annual incidence in The Netherlands ranges between 60,000 to 75,000 people.
- Trial name
- NCT02602093
- Testing
- Transforaminal Endoscopic Discectomy, Open Microdiscectomy
- Where
- Netherlands
- Volunteers
- 682 people
- Sponsor
- Amsterdam UMC, location VUmc
Intervertebral Disc Herniation, Back Pain
Immune Response During the Conservative and Minimal Invasive Treatment of Pain Caused by Lumbar Disc Herniation
Bulging of the intervertebral disc in the lumbar part of the spine is one of the most common degenerative changes of the spine in the elderly population, which causes various symptoms such as radicular pain.
- Conditions
- Intervertebral Disc Herniation, Back Pain, Analgesic Nephropathy, Inflammatory Response
- Trial name
- NCT06545812
- Testing
- Transforaminal epidural steroid injection, Physical therapy for disc herniation
- Where
- Croatia
- Volunteers
- 128 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Cervical Radicular Pain
Effect of Cervical Collar in Cervical Radicular Pain.
Objectives:The purpose of this study is to determine if use of nech collar (stiff or soft)will improve the possibility to obtain painrelief in patients with cervical radicular pain.
- Trial name
- NCT00395798
- Testing
- Soft or stiff cervical collar(device), neck school(behavior)
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Ullevaal University Hospital
Lumbar Disc Herniation
Elongation Longitudinaux Avec Decoaption Osteo-Articulaire (ELDOA) in Lumbar Disc Protrusion
The aim of this randomized controlled trial will be to determine the effectiveness of ELDOA for treating lumbar disc protrusion.
- Trial name
- NCT04043611
- Testing
- Conservative physical therapy management, ELDOA
- Where
- Pakistan
- Volunteers
- 29 people
- Sponsor
- Riphah International University
Lumbar Disc Herniation
Flexion-Distraction Technique
The aim of this study is to compare the effects of conventional physical therapy and flexion-distraction (Cox technique) on pain, functional capacity, and quality of life in patients with lumbar disc herniation (LDH) receiving…
- Trial name
- FDT (NCT06886334)
- Testing
- exercise, mobilization
- Volunteers
- 68 people
- Sponsor
- Istanbul Medipol University Hospital
Lumbar Spondylolisthesis, Degenerative Lumbar Scoliosis
A Study on the Clinical Use of a New Expandable OLIF Cage With Posterior Bone Grafting in Lumbar Spine Surgery
This clinical trial aims to evaluate the safety and effectiveness of a novel expandable OLIF (Oblique Lateral Interbody Fusion) cage with posterior bone grafting in patients with lumbar degenerative diseases.
- Conditions
- Lumbar Spondylolisthesis, Degenerative Lumbar Scoliosis, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- NCT07028099
- Testing
- Expandable OLIF cage with posterior bone grafting, Conventional OLIF cage
- Volunteers
- 340 people
- Sponsor
- The Affiliated Hospital of Qingdao University