Clinical trials: Disc Herniations
Lumbar Disc Herniation
Flexion-Distraction Technique
This prospective, two-center, non-randomized controlled study compared the effects of conventional physical therapy (CPT) and Cox flexion-distraction therapy (CFT) on pain, lumbar range of motion, disability, and health-related…
- Trial name
- FDT (NCT06886334)
- Testing
- exercise, Cox flexion-distraction therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istanbul Medipol University Hospital
Sciatica, Lumbar Disc Herniation
Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial
The goal of this clinical trial is to learn if electroacupuncture can improve sleep in people with chronic sciatica caused by lumbar disc herniation. It will also assess the safety of this treatment.
- Conditions
- Sciatica, Lumbar Disc Herniation, Insomnia
- Trial name
- NCT07576348
- Testing
- Electroacupuncture
- Volunteers
- 114 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation
The Effect of Expressive Touch and Music Applied After Lumbar Disc Hernia Surgery.
Patients undergoing lumbar hernia surgery will be divided into expressive touch, music and control groups. Pre-test and post-test pain levels, vital signs, and NIRS values of the patients will be measured.
- Trial name
- NIRS (NCT04765774)
- Testing
- Ekspressive touch, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Inonu University
Low Back Pain, Lumbar Disc Herniation
Efficacy and Duration of Pain Relief in Transforaminal and Lumbar Sympathetic Blocks
Low back pain is a symptom that is frequently seen in the general population and reduces the quality of life of patients. Conventional medical treatment for patients with low back pain includes oral medication, lifestyle…
- Trial name
- NCT06438952
- Testing
- Transforaminal steroid injection combined with lumbar sympathetic blockade, Transforaminal steroid injection only
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bezmialem Vakif University
Lumbar Disc Herniation
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy (PELD) for Lumbar Disc Herniation
Lumbar disc herniation compressed the nerve cause pain, numbness, weak legs called sciatica, which seriously decrease the quality of life and work efficiency.
- Trial name
- NCT05330806
- Testing
- Collagenase chemonucleolysis, Percutaneous endoscopic lumbar discectomy (PELD)
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Shenzhen People's Hospital
Intervertebral Disc Displacement, Electromyography
EMG Finding According to the Type of Lumbar Disc Herniation
Disc herniation is a common cause of low back pain and leg pain. Electromyography is the only test that can objectively examine nerve damage caused by a lumbar disc herniation.
- Trial name
- NCT04538807
- Testing
- electromyography
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Yeungnam University Hospital
Lumbar Disc Herniation
Effects of Whole-Body Electromyostimulation Application in Individuals With Lumbar Disc Hernia
To determine the effects of WB-EMS application on balance, pain, muscle strength, muscle endurance, flexibility, muscle shortening and quality of life in individuals with Lumbar Disc Hernia and compare it with individuals who…
- Trial name
- NCT04329598
- Testing
- Whole-Body Electromyostimulation Group, Exercise Group
- Where
- 2 sites in Cyprus
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Orthopedic Disorder of Spine
Evaluation of Outcomes of Discectomy With Dynesys in Treatment of Lumbar Disc Herniation
To explore the clinical outcomes of discectomy with dynamic neutralization system(Dynesys) on treatment of single-segmental lumbar disc herniation(LDH) versus simple discectomy.
- Trial name
- NCT04156867
- Testing
- Dynesys
- Volunteers
- 128 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Lumbar Disc Herniation
Effect of PNF and Lumbar Stabilization Exercises on Muscle Strength and Endurance in Lumbar Disc Hernia
Background/Objective: This study investigates the effect of lumbar stabilization and proprioceptive neuromuscular facilitation (PNF) training on muscle strength and muscle endurance.
- Trial name
- PNF (NCT03651440)
- Testing
- PNF, lumbar stabilization training, Physical Therapy
- Volunteers
- 64 people
- Sponsor
- Baskent University
Spine Disease, Back Pain
Investigation of the Efficacy of Treatments With Backup Device in Spine Pathologies
Our aim in this study is to examine the effectiveness of the Backup spine health device in spinal problems and compare it with traditional physical therapy methods.
- Conditions
- Spine Disease, Back Pain, Disc Herniation
- Trial name
- NCT06006377
- Testing
- electrotherapy, Backup therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uskudar University
Lumbar Disc Herniation
Quadratus Lumborum Block for Lumbar Spinal Surgery
Spine surgery in thoracolumbar region is one of the most common surgeries performed for the treatment of leg and back pain. Pain management is especially important for these patients since chronic pain often occurs after surgery.
- Trial name
- NCT04981301
- Testing
- Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Spinal Stenosis, Low Back Pain
Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis
This study tests the effectiveness of different treatments for the three most commonly diagnosed conditions of the lower backbone (lumbar spine).
- Trial name
- NCT00000411
- Testing
- Decompressive laminectomy, Non-surgical treatments
- Where
- 13 sites in United States
- Volunteers
- 289 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Lumbar Disc Herniation
Clinical Research on the Efficacy of Thread-embedding Acupuncture on Herniated Intervertebral Disc of Lumbar Spine
This clinical trial is designed to evaluate the efficacy and safety of thread-embedding acupuncture for treatment of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of life.
- Trial name
- NCT03236753
- Testing
- Thread-embedding Acupuncture (TEA)
- Where
- 4 sites in South Korea
- Volunteers
- 70 people
- Sponsor
- Kyunghee University Medical Center
Lumbar Disc Herniation
Brain Effect Mechanism of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI
The clinical symptoms of Lumbar Disc Herniation (LDH) can be effectively ameliorated through Spinal Manipulative Therapy (SMT), which is closely linked to the brain's pain-regulating mechanisms.
- Trial name
- NCT06277739
- Testing
- Spinal Manipulative Therapy
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhou Xingchen
Lumbar Disc Herniation
A Comparison Between Biportal and Uniportal Endoscopic Lumbar Discectomy
This study aims to provide a detailed comparison between different methods of lumbar discectomy by the use of different types of spine endoscopy to evaluate the benefits and drawbacks of each type
- Trial name
- NCT07151651
- Testing
- Endoscopic lumbar discectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Prolapsed Intervertebral Disc
Effects of Lumbar Traction on the Straight Leg Raise Test and Pain
Disc prolapse causes impairment of function by nerve root compression compelling the patient to seek medical advice for low backache.
- Trial name
- NCT04728685
- Testing
- Mechanical Traction
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- King Saud University
Lumbar Disc Herniation
Erector Spinae Plane Block and Modified-Thoracolumbar Interfascial Plane Block Following Lumbar Spinal Surgery
Ultrasound (US)-guided peripheral nerve blocks have been used increasily due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Trial name
- NCT04073095
- Testing
- Erector spinae plane block (Group E), modified-thoracolumbar interfascial plane block (Group T)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Low Back Pain, Kinesiophobia
Investigation of the Effectiveness of Dynamic Neuromuscular Stabilization Exercises After Lumbar Disc Herniation Surgery
The aim of the study is to investigate the effects of dynamic neuromuscular stabilization exercises on pain, functionality and fear in individuals who have undergone lumbar disc herniation surgery.
- Trial name
- NCT06005948
- Testing
- exercise, control
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uskudar University
Disc Prolapse, Pain
ADALISKIAS: Adalimumab for Acute Disc Prolapse
Aims: To study the efficacy and safety of adalimumab versus placebo in the treatment of acute disc prolapse will be will be compared up to 12 months after the start of study drug treatment.
- Trial name
- NCT01510548
- Testing
- Adalimumab injections for acute disc prolapse patients
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Kuopio University Hospital